Abstract:
:Successful delivery of progenitor cells to the injury zone is a prerequisite for any effect of myocardial regeneration therapy. This key issue, however, has received far less attention than, for instance, a potential need for cell type selection or ex-vivo expansion, the optimal timing of cell application or multimodal functional evaluation after cellular transplantation. By combining myocardial perfusion scintigraphy, magnetic resonance imaging and 99Tc-HMPAO-labelled autologous bone marrow-derived CD34+ cells visualisation, we show in a 63-year-old man with a large anterior myocardial infarction that transcoronary applied cells (via the central lumen of an inflated over-the-wire balloon positioned in the stent implanted in primary PCI) graft preferentially to the infarct border zone. This is consistent with the idea that the area of myocardial 'irreversible' injury (i.e. the no-perfusion zone on perfusion scintigraphy or late enhancement zone on magnetic resonance) remains largely inaccessible to transcoronary-applied cells; thus other techniques need to be considered if the cell delivery is aimed at the zone of irreversible injury. The potency of such combined high-resolution visualisation provides grounds for comparing the efficacy of different methods of cell delivery after a recent myocardial infarction in man.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Musiałek P,Tracz W,Kostkiewicz M,Tekieli Ł,Szot W,Klimeczek P,Banyś P,Zebzda A,Majka M,Walter Z,Olszowska M,Pieniazek P,Pasowicz Msubject
Has Abstractpub_date
2008-01-01 00:00:00pages
73-7issue
1eissn
0022-9032issn
1897-4279pii
9799journal_volume
66pub_type
杂志文章abstract:BACKGROUND:Efficacy of carotid endarterectomy (CEA) in prevention of stroke in patients with carotid artery stenosis has been confirmed in randomised trials. Carotid artery stenting (CAS) is a routine clinical practice and recent results of CAS are not worse than CEA. Moreover, percutaneous transluminal angioplasty (PT...
journal_title:Kardiologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:2008-03-01 00:00:00
abstract::A case of a 70 year old female with permanent atrial fibrillation and a history of stroke is presented. Echocardiography showed the presence of an oval mass in the left atrium which suggested thrombus or atrial myxoma. The patient underwent urgent cardiac surgery during which a long thrombus, originating from the left...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Out‑of‑hospital cardiac arrest (OHCA) is a severe medical condition. Prehospital care plays an essential role in patient survival. AIMS:First, the study aimed to evaluate cases of OHCA managed by cardiopulmonary resuscitation (CPR) attempts in Poland in 2018, including their frequency and patient outcomes i...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.15241
更新日期:2020-05-25 00:00:00
abstract::Chest irradiation and chemotherapy may lead to precocious coronary artery disease due to accelerated atherosclerosis or fibrointimal hyperplasia. Three cases of women (43, 50, and 53 years old) without typical risk factors for cardiac disease admitted to hospital due to acute coronary syndrome are described. Two of th...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Acute myocardial infarction (AMI) causes remodelling of the left ventricle (LV). Restoration of patency of an infarct-related artery by percutaneous coronary interventions (PCI) may prevent or inhibit cardiac remodelling. AIM:To assess LV contractility and function by serial echocardiographic examinations. ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2003-11-01 00:00:00
abstract::Cardiopulmonary exercise testing (CPET) is an important diagnostic tool in contemporary clinical practice. This document presents an expert opinion from the Working Group on Cardiac Rehabilitation and Exercise Physiology of the Polish Cardiac Society concerning the indications, performance technique, and interpretatio...
journal_title:Kardiologia polska
pub_type: 杂志文章,实务指引
doi:10.33963/KP.14889
更新日期:2019-08-23 00:00:00
abstract::Percutaneous coronary intervention of chronic total occlusion (CTO) is one of the greatest challenges in coronary interventions. Retrograde wiring is suggested as a solution to improve the success rate of intervention for CTO. We experienced the coronary perforation during antegrade wiring at the CTO lesion and sealed...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Despite the increasing number of patients after percutaneous coronary intervention (PCI) requiring coronary artery bypass grafting (CABG), studies on the impact of these procedures on surgical revascularisation outcomes are sparse. Furthermore, advances in cardiology require reassessment of their potential p...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2018.0039
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Red blood cell distribution width (RDW) is a risk factor related to adverse outcome in patients with heart failure (HF). Less is known about its influence in patients in their first hospitalization by HF. Aims: Our objective was to investigate the prognostic role of RDW in elderly patients firstly hospital...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.14818
更新日期:2019-06-25 00:00:00
abstract::According to current guidelines surgical revascularisation is a gold standard of treatment in patients with multivessel and left main coronary disease. Hybrid revascularisation, in two stages: first - minimally invasive direct coronary artery bypass grafting procedure with left internal mammary artery conduit to left ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Although increased left atrial size (LA) has been long regarded as one of the factors negatively influencing the long-term maintenance of sinus rhythm (SR) following cardioversion (CV) of atrial fibrillation (AF), some reports suggested that CV might be effective also in patients with large LA.Aim. We sought...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Platelets play a key role in the development and progression of cardiovascular disease. The degree of platelet activation may be assessed by platelet indices such as platelet count, mean platelet volume (MPV) and platelet distribution width (PDW). AIM:To evaluate the relationship between platelet indices an...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.2013.0293
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Obstructive sleep apnoea syndrome (OSAS) is reported to be associated with hypertension, coronary artery disease, atrial fibrillation, and heart failure. Galectin-3 plays an important role in the regulation of inflammation, development of cardiac fibrosis, and remodelling. A significant relationship between ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2016.0185
更新日期:2017-01-01 00:00:00
abstract::Two extremely rare cases of adults with univentricular hearts of right ventricular morphology are presented. Pathogenesis and pathophysiology of univentricular circulation as well as anatomic variants, short information on prognosis and management are briefly discussed. Echocardiographic diagnosis of univentricular he...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2004-09-01 00:00:00
abstract::We present a case of a 70 year-old male with B-cell lymphoma of which the first clinical presentation was cardiac infiltration. The patient underwent full chemotherapy with complete tumour regression. Kardiol Pol 2011; 69, 10: 1063-1065. ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::The local coronary flow in 42 patients (mean age: 59 +/- 9 years) with ischemic heart disease was assessed by means of an 0.018" intracoronary Doppler guidewire. Study population was divided into two groups: group I--"normal vessels" (diameter stenosis < 30%) and group II--"stenosis vessels" (diameter stenosis > 60%)....
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:Ventricular premature beats (VPBs) are one of the most common rhythm abnormalities. Structural heart diseases such as myocardial hypertrophy and left ventricular dysfunction are associated with VPBs. However, the exact mechanism of VPBs in patients without structural heart disease has not been revealed yet. ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2015.0025
更新日期:2015-01-01 00:00:00
abstract::Infective endocarditis (IE) is an infectious disease, which leads to death when is untreated. In most cases IE is caused by typical bacteria. IE caused by atypical bacteria is rare. In this paper, we describe a female patient with IE caused by Erysipelothrix rhusiopathiae (ER). Due to inflammation and leaflets' damage...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2004-02-01 00:00:00
abstract::A case of a 66-year-old male with acute myocardial infarction (MI) treated with streptokinase is presented. Due to the recurrence of angina six days from the acute phase of MI, the patient underwent coronary angiography which revealed critical stenosis of the left anterior descending coronary artery. During intracoron...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2005-03-01 00:00:00
abstract::Two cases of coronary artery fistulas diagnosed during coronary angiography are reported and symptomatology of this disease is discussed. The first described patient suffered mainly from chest pain and dyspnoe, the second - from paroxysmal atrial fibrillation. Indications for pharmacological and surgical treatment are...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00
abstract::After an initial learning experience in the early 70's, radial artery is now used as the second arterial graft of choice (after both ITAs). The aim of the study was to compare patency rates of venous and arterial grafts--especially radial artery--in mid-term follow up period. 19 patients with stable angina and 11 with...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Genetic C3435T polymorphism of the multidrug resistance gene-1 (MDR-1) limits oral bioavailability of clopidogrel and influences prognosis in patients with myocardial infarction. AIM:To assess the effects of C3435T polymorphism on platelet reactivity and prognosis in patients with acute coronary syndromes t...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Analysis of pathophysiological mechanisms responsible for vaso-vagal reaction reveals a close relationship between neurocardiogenic syncope and the preceding abnormalities of autonomic nervous system (ANS). Therefore, the interest in the assessment of heart rate variability (HRV) for detecting and establishi...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract::119 hypertensive patients were examined by 24-hour ambulatory blood pressure monitoring (ABPM) and traditional (casual) blood pressure measurements. The echocardiographic examination was also performed. Mean and maximal systolic and diastolic blood pressure values, systolic and diastolic pressure amplitude as well as ...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1993-04-01 00:00:00
abstract::Sphygmomanometer S is the microcomputer device measuring blood pressure for (BP) on the basis of amplitude height and morphology of pulse waves, registered by the pulse converter placed in the air system of a cuff. The letter S stands the sphygmo-oscillographic method used in BP measurement (11). Sphygmomanometer S ma...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The presence of accessory pathways (APs) is a risk factor for sudden cardiac death and other clinical complications. AIMS:We aimed to characterize all adverse events likely related to the presence of APs in patients referred for AP ablation and to identify risk factors for malignant arrhythmias. METHODS:We...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.15161
更新日期:2020-03-25 00:00:00
abstract::The value of radioimmunoassay for creatine kinase BB isoenzyme (CK-BB) determination in early diagnosis of acute myocardial infarction was estimated. The clinical material consisted of 35 randomly selected patients admitted to a coronary care unit during the 4 h after chest pain suspected for myocardial infarction. In...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Patients with advanced lower limb ischaemia are, at present, mainly treated using revascularisation. AIM:The aim of the study was to investigate whether the dynamics of blood flow in below-the-knee (BTK) arteries assessed by angiography correlate with clinical outcomes after a 12-month follow-up in patients...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2018.0212
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Previous reports of pharmacological treatment concerning the surgical approach to coronary artery disease emphasise the underused possibilities of pharmacological treatment. AIM:To evaluate trends in the level of compliance between the pharmacological treatment administered in clinical practice and formal g...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2015.0094
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Diabetes mellitus in patients with myocardial infarction affects in-hospital and late mortality. It has been shown that the glucose level on admission can also affect prognosis. This conclusion was based on an analysis performed on a heterogeneous group of patients, treated not only with percutaneous coronar...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2007-09-01 00:00:00