Abstract：
BACKGROUND:Ventricular premature beats (VPBs) are one of the most common rhythm abnormalities. Structural heart diseases such as myocardial hypertrophy and left ventricular dysfunction are associated with VPBs. However, the exact mechanism of VPBs in patients without structural heart disease has not been revealed yet. Epicardial fat tissue (EFT) is a visceral fat around the heart. Increased EFT thickness is associated with myocardial structural and ultrastructural myocardial abnormalities, which may play a role in the development of VPBs. AIMS:To evaluate the possible relationship between EFT thickness and frequent VPBs. METHODS AND RESULTS:The study population consisted of 50 patients with VPBs and 50 control subjects. Frequent VPBs were defined as the presence of more than 10 beats per hour assessed by 24-h Holter electrocardiography monitoring. EFT thickness was measured by transthoracic echocardiography. Multivariable logistic regression analysis was used to assess factors related with frequent VPBs. Baseline demographic and biochemical features including age, gender, and rates of hypertension and diabetes mellitus were similar in both groups. EFT thickness was significantly higher in patients with frequent VPBs than in controls (3.3 ± 1.3 mm vs. 2.2 ± 0.8 mm, p < 0.001). In multivariable logistic regression analysis, EFT thickness was independently associated with VPB frequency (B = 1.030, OR = 2.802, p < 0.001). CONCLUSIONS:Patients with frequent VPBs had increased EFT thickness compared to control subjects. EFT thickness was independently associated with frequent VPBs.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Kırış A,Turan OE,Kırış G,İlter A,Öztürk M,Aydın M,Kaplan Ş,Kutlu M,Gedikli Ödoi
10.5603/KP.a2015.0025subject
Has Abstractpub_date
2015-01-01 00:00:00pages
527-32issue
7eissn
0022-9032issn
1897-4279pii
VM/OJS/KP/9024journal_volume
73pub_type
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