Abstract：
BACKGROUND:Acute myocardial infarction (AMI) causes remodelling of the left ventricle (LV). Restoration of patency of an infarct-related artery by percutaneous coronary interventions (PCI) may prevent or inhibit cardiac remodelling. AIM:To assess LV contractility and function by serial echocardiographic examinations. METHODS:The study group consisted of 61 patients (47 males, mean age 60+/-10 years) with acute MI treated with direct PCI. Echocardiography was performed 6-8 days after PCI, and 1, 6 and 12 months thereafter. RESULTS:LV ejection fraction increased significantly at the end of the first month in comparison with the baseline examination whereas EF values obtained after 6 months and after 1 year were not significantly different. Wall motion score index showed a significant improvement after one month, whereas it did not show any further improvement when measured after 6 or 12 months after AMI. The baseline LV end-diastolic diameter was 49+/-6 mm and did not change after one or 6 months, whereas it increased significantly 12 months after AMI. The baseline LV end-systolic diameter was 37+/-5 mm. At the one-month and six-month examinations it was similar to the baseline values but increased significantly to 38+/-6 mm after one year. CONCLUSIONS:These results confirm the beneficial effects of PCI-induced infarct-related artery patency on LV remodelling after AMI.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Nechvatal L,Hlinomaz O,Groch L,Hornacek I,Sitar J,Orban M,Petrikovits Esubject
Has Abstractpub_date
2003-11-01 00:00:00pages
397-401issue
11eissn
0022-9032issn
1897-4279journal_volume
59pub_type
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