Abstract：
BACKGROUND:Contrast-induced nephropathy is a relatively common complication occurring after various procedures requiring contrast agent injection, especially in patients with pre-existing renal failure. AIM:This pilot study was designed to assess the effects of a high intravenous dose of N-acetylcysteine (NAC) on plasma creatinine concentration. METHODS:Twenty patients with pre-existing renal insufficiency were given NAC at a dose of 100 mg/kg. No contrast agent was given to 10 patients (Group A), whereas 10 patients received contrast at the time of coronary angiography (Group B). Changes in plasma creatinine were assessed at 3 hours and one day following NAC administration. RESULTS:In Group B, NAC prevented creatinine increase: baseline levels were 210.98+/-77.33 micromol/L, 200.26+/-71.94 micromol/L (NS) after 3 hours, and 203.80+/-83.94 micromol/L 24 hours later (NS). The following was seen in Group A patients: 201.21+/-42.28 micromol/L, 190.31+/-42.74 micromol/L (p<0.01), and 170.08+/-45.53 micromol/L (p<0.01), respectively. CONCLUSION:The results of this study confirm the effectiveness of NAC in prevention of contrast agent-induced renal impairment. In addition, we demonstrated the beneficial effects of NAC on renal function in patients who were not exposed to contrast agent. This pilot study should provide the basis for more comprehensive research and, also, for safe clinical practice.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Sochman J,Krizova Bsubject
Has Abstractpub_date
2006-06-01 00:00:00pages
559-64; discussion 565-6issue
6eissn
0022-9032issn
1897-4279pii
6219journal_volume
64pub_type
临床试验,杂志文章abstract：BACKGROUND:Lipid lowering therapy with statins is beneficial because of improvement in lipoprotein concentrations and additional pleiotropic effects. However, less is known about the pleotropic effect of fibrates. AIM:To investigate the effects of fenofibrate therapy on inflammatory markers and serum paraoxonase activ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2005-06-01 00:00:00
abstract：:We present a case of the left atrial myxoma 6 years after atrial fibrillation ablation. The initial diagnosis of the mass revealed on echocardiography was a thrombus. Failure of anticoagulant treatment and transesophageal echocardiography led to diagnosis of myxoma, confirmed intraoperatively and histologically. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Desmin plays one of the key roles in cardiomyocytes. The protein protects the integration of the cell and has the following actions: mechanical, structural and regulatory. Observed abnormalities of its activity have been associated with worsening of heart failure (HF). AIM:Evaluation of desmin activity dete...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2007-03-01 00:00:00
abstract：:Although considerable data exist regarding the function of prosthetic heart valves (PHV) at rest, few data exist regarding the response to exercise. Thus, we studied by Doppler echocardiography 81 asymptomatic patients with PHV (46 mitral, 45 aortic) of varying type and 20 normal persons before and after symptom limit...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：BACKGROUND:Cardiac rehabilitation (CR) is an important element of heart failure (HF) treatment although the mechanisms of its beneficial effects remain debatable. AIM:To evaluate the haemodynamic effects of CR measured by impedance cardiography in patients with HF. METHODS:Study group included 50 HF patients (aged 56...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:Slow ventricular tachycardia (VT), which is below the detection rate of implantable cardioverter-defibrillator may cause haemodynamical instability, when pharmacological agents or antitachycardia pacing are unsuccessful, electrical cardioversion is necessary. We present another method of termination of slow VT by ICD,...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2009-11-01 00:00:00
abstract：:Stent fracture (SF) has been suggested to be an unusual cause of restenosis after drug eluting-stent implantation. However, angiographically visible SF after bare metal stent (BMS) implantation is extremely rare. We present a case of a 58 year-old male patient who presented with unstable angina secondary to a SF of a ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Endothelial dysfunction (ED) may indirectly influence the outcome of patients with coronary artery disease. AIM:To assess the influence of cardiac rehabilitation (CR) on endothelial function in patients after ST-segment elevation myocardial infarction (STEMI). METHODS:Twenty-nine patients scheduled for CR ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0177
更新日期：2016-01-01 00:00:00
abstract：:The coronavirus disease 2019 (COVID-19) pandemic affects anticoagulation not only in those infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but also in most patients who require daily anticoagulant therapy and are facing substantial limitations in medical care these days. Concomitant venous t...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15425
更新日期：2020-06-25 00:00:00
abstract：:Endothelin is a family of potent vasoconstrictor peptides of vascular endothelial origin. Although it has been proposed that the vasoconstrictor effects of endothelin are produced at the local vascular level, the current study was performed to test the hypothesis that plasma endothelin concentrations are elevated in p...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：:Hemorrhagic stroke is a frequent cause of morbidity and mortality in Poland. It results from disruption of intracranial vessel wall continuity. We report a case of 66-years-old man with prosthetic aortic valve after three ischemic strokes treated with acenocoumarol who was admitted to hospital with vertigo and motoric...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:Patients hospitalized due to heart failure (HF) exacerbation tend to have a poor prognosis. Most previous studies were performed in large clinical centers and detailed analyses of HF patients hospitalized in district general hospitals are lacking. AIMS:The aim of this study was to assess the outcomes of pat...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15763
更新日期：2021-01-19 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Bisoprolol is one of the most widely used beta-blockers characterised by cardioselectivity, and it has no intrinsic sympathomimetic activity. It is commonly used in the treatment of coronary heart disease and heart failure. AIM:The aim of study was to assess the bioequivalence of the film-coated tablets con...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2016.0106
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2004-10-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2009-05-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2014.0061
更新日期：2014-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2019.0041
更新日期：2018-12-20 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2003-12-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-04-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2005-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2008-10-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 传,历史文章,信件
doi：
更新日期：2010-07-01 00:00:00
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journal_title：Kardiologia polska
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doi：10.5603/KP.2013.0226
更新日期：2013-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
abstract：:In 3 post-MI patients with multiple premature ventricular complexes, programmed transoesophageal pacing generated the arrhythmia and an ecg tracing was taken. Analysis of the ecg suggested that simultaneous activation of two pathways within the A-V node maybe the cause of the arrhythmia. The activation signal reaches ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
