Two-year prognosis of patients hospitalized with decompensated heart failure in a district general hospital.

Abstract:

BACKGROUND:Patients hospitalized due to heart failure (HF) exacerbation tend to have a poor prognosis. Most previous studies were performed in large clinical centers and detailed analyses of HF patients hospitalized in district general hospitals are lacking. AIMS:The aim of this study was to assess the outcomes of patients admitted with HF exacerbation in a district general hospital. METHODS:We retrospectively enrolled patients hospitalized due to HF exacerbation during 2010-2011 (191 patients) and 2016-2017 (203 patients). The primary and secondary endpoints were all-cause mortality and re-hospitalization due to HF exacerbation within a two-year follow-up period. RESULTS:Compared to patients hospitalized in 2010-2011, those hospitalized in 2016-2017 had better clinical parameters and pharmacological treatment; however, the rate of implantable cardioverter-defibrillator and resynchronization devices remained low. The overall mortality decreased from 44% in 2010-2011 to 33% in 2016-2017 ( P < 0.029) and the number of re-hospitalizations increased from 26% to 41% (P <0.001). Male sex, low systolic blood pressure, symptoms of right HF, and renal dysfunction were independent risk factors for the primary endpoint. Symptoms of right HF, renal dysfunction, left ventricular ejection fraction < 24 %, and low systolic blood pressure independently predicted the secondary endpoint. CONCLUSIONS:The prognosis of patients hospitalized due to decompensated HF in a regional district hospital was poor. Despite some improvement in pharmacological treatment, which probably led to a reduction in all-cause mortality, there was a low rate of implantable electrical devices and a high rate of re-hospitalizations due to HF exacerbation which warrant further evaluation.

journal_name

Kardiol Pol

journal_title

Kardiologia polska

authors

Dobrowolska M,Miękus P,Świątczak M,Raczak G,Daniłowicz-Szymanowicz L

doi

10.33963/KP.15763

subject

Has Abstract

pub_date

2021-01-19 00:00:00

eissn

0022-9032

issn

1897-4279

pub_type

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