Abstract:
:The functional and morphological changes in myocardium of diabetic patients is caused by diabetic macroangiopathy, diabetic microangiopathy, autonomic neuropathy and metabolic disorders. Mechanism of these changes in the course of diabetes is not fully known. To determine whether there are myocardial ultrastructure differences between patients with diabetic cardiomyopathy (normal coronary angiograms) and diabetic patients with coronary artery disease, electron microscopy examination were performed of 70 sections received from seven biopsied patients (1F, 6M), average age 53 years (range: 42-60) with diabetes type II WHO (group A) without clinical evidence of prior coronary artery disease and hypertension, and 100 sections from 10 patients (2F, 8M), average age 54 years (range: 42-65) with diabetes and coronary atherosclerosis. These patients had clinical evidence of heart failure and were submitted to bypass-graft operations (group B). Endomyocardial biopsy tissues were obtained from the right ventricle without complications either during or after the procedure. Obtained biopsy specimens were fixed in 3% glutaraldehyde stabilized with 1M cacodylate buffer at pH 7.4, postfixed in 1% OsO4 on cacodylate buffer. The materials were then dehydrated and embedded in epon. The Irvin-Fischer test for statistical analysis was used. A p value < 0.05 was considered significant. The presence of focal mild loss of myofibrils (+) was statistically more frequent in the patients in A group (p < 0.05). It was found in 86% (6/7) of cases in A group, while in the B group was observed in 20% of (2/10) cases.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Pasyk S,Wojnicz R,Szafranek A,Zielińska T,Krupa Hsubject
Has Abstractpub_date
1993-12-01 00:00:00pages
439-45; discussion 446issue
12eissn
0022-9032issn
1897-4279journal_volume
39pub_type
杂志文章abstract::A case of a 45-year-old male patient with hypertrophic cardiomyopathy (HCM) is presented. The patient suffered from chest pain since his childhood. He was hospitalised several times but accurate diagnosis was not established for nearly 20 years. The ECG changes were interpreted as myocardial ischaemia. The proper diag...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Heat shock protein (Hsp) 27 expression in cardiomyocytes increases in response to ischaemia. The extracellular release of Hsp27 from cardiomyocytes is proportional to its intracellular levels. AIM:To assess the influence of significant coronary artery disease (CAD), which by definition results in chronic my...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND AND AIM:To evaluate myocardial function with the use of tissue Doppler echocardiography in children with primary hypertension. METHODS:A total of 64 subjects (34 with hypertension, 30 control) underwent echocardiographic evaluation of systolic and diastolic function with the use of standard and tissue Doppl...
journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2014.0189
更新日期:2015-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Patent ductus arteriosus (PDA) occurs more frequently in premature infants. Depending on the degree of prematurity, these children often have other serious comorbidities that could have a significant impact on surgical outcome. AIM:This study aimed to evaluate the clinical results of surgical ligation of PD...
journal_title:Kardiologia polska
pub_type: 杂志文章
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.15102
更新日期:2020-01-24 00:00:00
abstract:UNLABELLED:The clinical profile of 19 patients with dilated cardiomyopathy from 2 to 18 years old (mean age 13.4 +/- 4 years) was reviewed to detect any factors that might be predictive for their survival. Follow-up study ranged from 5 to 105 months (mean 39 +/- 33 months). All patients received digitalis + diuretics, ...
journal_title:Kardiologia polska
pub_type: 杂志文章,评审
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更新日期:1991-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.14814
更新日期:2019-05-24 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.2013.0164
更新日期:2013-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章,评审
doi:
更新日期:1989-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2014.0061
更新日期:2014-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章,评审
doi:10.33963/KP.14804
更新日期:2019-04-18 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.33963/KP.15645
更新日期:2020-12-23 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 临床试验,杂志文章
doi:
更新日期:2007-04-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:1989-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:
更新日期:2012-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:10.5603/KP.a2016.0019
更新日期:2016-01-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2009-06-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:2009-05-01 00:00:00
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journal_title:Kardiologia polska
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
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pub_type: 杂志文章
doi:10.5603/KP.a2016.0139
更新日期:2017-01-01 00:00:00