Abstract：
:Apelin is a recently discovered biologically active peptide present in several isoforms that are agonists for orphan receptor APJ. Apelin and APJ receptor were found in the central nervous system and in different peripheral tissues. In the cardiovascular system the peptide is present both in the heart and in the endothelium and smooth muscles cells of the vascular wall. Acting on cardiomyocytes apelin exerts positive inotropic effect, in the endothelium it releases nitric oxide, which mediates its vasodilatory action, while acting directly on smooth muscles cells it causes vasoconstriction. Apelin interacts with other compounds regulating blood pressure; for instance with angiotensin II, vasopressin, and with the sympathetic nervous system. Special attention is focused on the possibility of positive role of apelin in hypertension, initial stages of heart failure and ischaemic heart disease. Synthesis of apelin in adipocytes permits to include this peptide among adipokines. In the adipose tissue its production is increased in obesity and by insulin. It appears that apelin may play essential role in pathogenesis of insulin-resistant obesity. In patients with type 2 diabetes apelin improves glucose tolerance in initial stages of the illness. However, further experimental and clinical studies are required for full evaluation of significance of positive and negative aspects of the role of apelin in the cardiovascular and metabolic diseases.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Cudnoch Jędrzejewska A,Czarzasta K,Gomółka R,Szczepańska Sadowska Esubject
Has Abstractpub_date
2011-01-01 00:00:00pages
89-93eissn
0022-9032issn
1897-4279journal_volume
69 Suppl 3pub_type
杂志文章,评审abstract：:In 75 patients 24-hour ecg monitoring value was compared with exercise test in diagnostics of postinfarction silent ischemia. Results compatibility of both comparing examinations was 79% with regard to only painless ischemia (p less than 0.001) and 91% to both estimated painless or painful episodes (p less than 0.001)...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：INTRODUCTION:In patients treated with permanent pacing, the electrode is typically placed in the right ventricular apex (RVA). Published data indicate that such electrode placement leads to an unfavourable ventricular depolarization pattern, while right ventricular outflow tract (RVOT) pacing seems to be more physiolog...
journal_title：Kardiologia polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2006-10-01 00:00:00
abstract：:Precordial maps of R, S and Q waves were performed in 43 children with congenital and acquired cardiac defects, with cardiomyopathies and also in 55 healthy children. Two subgroups with the left and right ventricular hypertrophies were separated basing on a standard electrocardiogram. Multilead electrocardiogram (M60-...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:We report a case of a 59 year-old man with hypertrophic cardiomyopathy who developed a pathological structure attached to the lead of cardioverter-defibrillator that has been detected by echocardiography. The authors describe a difficult differential diagnostic process aiming at the differentiation between cardiac dev...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND AND AIM:The aim of this study is to evaluate the effect of epicardial adipose tissue (EAT) thickness on left ventricular diastolic functions in patients with normal coronary arteries (NCA) proven by angiography. METHODS:We selected study patients who were referred to coronary angiography due to typical ches...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2016.0139
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:This report comprises an analysis of results of examinations performed as a part of a cardiovascular disease prevention programme funded by the National Health Fund. AIM:To determine the relationship between body mass index (BMI) and blood pressure, blood glucose and lipid metabolism abnormalities in an eth...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：:A case of a 47 year old male with a history of closed mitral commissurotomy performed in 1991 and implantation of prosthetic mitral and aortic valves in 1999, is presented. Three years after the second procedure the patient developed dilatation of superior vena cava and internal jugular vein. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:Kawasaki disease is the most common cause of acquired heart disease in children in developed countries. The incidence of Kawasaki disease varies from 180 in Japan through 20 in United States to 5-8 in the European countries per 100,000 children younger than 5 years of age. AIM:To evaluate cardiac complicati...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0136
更新日期：2016-01-01 00:00:00
abstract：:24-hours Holter's ecg monitoring was performed in 79 patients with the hypertrophic cardiomyopathy. Ventricular arrhythmias were recorded in 75.9% of patients, including those revealed in the second recording in 29.5% of patients. Subsequent ecg monitoring was especially useful in detection of complex forms of ventric...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Percutaneous balloon aortic valvuloplasty (BAV) is an effective method of treatment for aortic stenosis in children. AIMS:This study aimed to assess the long‑term results of BAV in various age groups in the pediatric population. METHODS:This retrospective study included 68 patients (newborns, infants, and ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15245
更新日期：2020-06-25 00:00:00
abstract：BACKGROUND:The CHADS2 and CHA2DS2-VASc scores were shown to predict mortality in patients with atrial fibrillation. However, pathophysiology and treatment outcomes of atrial fibrillation and typical atrial flutter (AFL) differ. Consequently, the prognosis of patients with AFL can also be different. AIMS:The aim of the...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15102
更新日期：2020-01-24 00:00:00
abstract：BACKGROUND:Immediate initiation of cardiopulmonary resuscitation (CPR) increases chances of restoring spontaneous circulation and survival after out‑of‑hospital cardiac arrest (OHCA). For some refractory cases, extended cardiopulmonary resuscitation (ECPR) may be a promising option. AIMS:The aim of the study was to es...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15433
更新日期：2020-09-25 00:00:00
abstract：:Of 218 patients with arterial hypertension, who responded to monotherapy with prazosin (Minipress) during the first 3 months, 178 persons completed the 12-month treatment according to the study protocol. In 9 patients (4.1%) treatment was discontinued because of increase of blood pressure and/or side effects. In the r...
journal_title：Kardiologia polska
pub_type： 临床试验,杂志文章,多中心研究
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:The chain of survival is a set of most important factors affecting survival after an out-of-hospital cardiac arrest (OHCA). Recognising the difficulties in applying the chain is the key to improving outcomes. Early return of spontaneous circulation (ROSC) after a cardiac arrest is a fundamental factor for pa...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2016.0001
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Patients suffering from cardiogenic shock, with no response to conventional therapy, may significantly improve when put on support devices such as extracorporeal membrane oxygenation (ECMO), which maintains systemic and pulmonary circulation, and decongests the heart. This publication presents authors' own e...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2016.0087
更新日期：2016-01-01 00:00:00
abstract：:N/A. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.2018.0220
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Arterial hypertension is one of the most common chronic diseases in the western world, affecting more than 25% of the adult population. AIM:The aim of this study was to assess changes in arterial blood pressure (BP) levels in hypertensive patients, after ablation of nerve terminals in renal arteries, using ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2017.0100
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Statins have anti-inflammatory and anti-platelet effects, which are known as non-lipid effects. Statin treatment can decrease endogenous inflammatory response. AIM:To study the effects of atorvastatin on matrix metalloproteinase-9 (MMP-9) and high sensitive C-reactive protein (hs-CRP) - markers of the prote...
journal_title：Kardiologia polska
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:In patients with chronic stable coronary artery disease (CAD), well‑developed coronary collateral circulation (CCC) is known to reduce long‑term mortality. AIMS:The objective of this study was to determine the relationship of serum calprotectin (S100A8 / S100A9), angiopoietin‑1 (Ang‑1) and angiopoietin‑2 (A...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15023
更新日期：2019-12-19 00:00:00
abstract：:Twenty-five years after the first publication of the strong natriuretic effect of rat cardiac atria extract, natriuretic peptides play an important part in everyday, not only cardiological, practice. In the current review the authors briefly describe the role of natriuretic peptides (ANP, BNP, and CNP) in clinical pra...
journal_title：Kardiologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2006-10-01 00:00:00
abstract：:Immunological response against myocardial antigens was assessed in 12 patients (pts) (9 males, 3 females, aged 24-62 years) with aortic homografts (AH) and 36 pts (29 males, 7 females, aged 26-61 years) with aortic valve prostheses (AVP). In all pts a titre of anti-myocardial antibodies, a concentration of free-circul...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：:A case of a 49-year-old female with patent ductus arteriosus complicated by severe pulmonary hypertension is presented. The patent ductus arteriosus was successfully closed by the Amplatzer duct occluder. The physical capacity improved from functional NYHA class III at baseline to class I one month after the procedure...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:A Fontan-type operation, i.e. a connection of the systemic veins and pulmonary arteries without subpulmonary ventricle, with different surgical techniques, is nowadays the only treatment option for patients with a functionally univentricular heart (UVH). Understanding the development of pulmonary arteries in...
journal_title：Kardiologia polska
pub_type： 临床试验,杂志文章
doi：10.5603/KP.2013.0121
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Previous reports of pharmacological treatment concerning the surgical approach to coronary artery disease emphasise the underused possibilities of pharmacological treatment. AIM:To evaluate trends in the level of compliance between the pharmacological treatment administered in clinical practice and formal g...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0094
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Diabetes mellitus in patients with myocardial infarction affects in-hospital and late mortality. It has been shown that the glucose level on admission can also affect prognosis. This conclusion was based on an analysis performed on a heterogeneous group of patients, treated not only with percutaneous coronar...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：:Isolated critical stenosis of left main coronary artery (LMCA) due to atherosclerosis is very rare and affects about 0.2% of patients. We present the case of a 39-year-old, non-smoker women with risk factors for diseases of the cardiovascular system in the form of hypercholesterolaemia and hypertension, in addition to...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.2013.0164
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Psychosocial risk factors for cardiovascular disease (CVD) are known to cluster in individuals, but the effect of cumulative exposure has not been thoroughly described in terms of CVD risk. AIMS:The aim of the study was to assess the relationship between accumulation of psychosocial risk factors such as low...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.14814
更新日期：2019-05-24 00:00:00
abstract：:We present a 46-year-old male patient with complete atrio-ventricular block. A inflammatory etiology was suspected and finally lyme carditis was diagnosed. The conduction abnormalities disappeared with antibiotic treatment and a pacemaker implantation was not needed. Further follow-up of two years was uneventful. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.2013.0020
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:The effective antihypertensive therapy is one of the main goals of treatment in metabolic syndrome (MS) because hypertensive patients with MS are of high cardiovascular risk. The impedance cardiography (ICG), as a modern technique of non-invasive haemodynamic monitoring, enables the evaluation of cardiac ind...
journal_title：Kardiologia polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2012-01-01 00:00:00
abstract：:We present a patient at risk of sudden cardiac death in whom ventricular fibrillation was effectively treated by wearable automatic defibrillator. We discuss the technical aspects of the device, current indications for this therapy and outcomes. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
