Abstract：
:Immunological response against myocardial antigens was assessed in 12 patients (pts) (9 males, 3 females, aged 24-62 years) with aortic homografts (AH) and 36 pts (29 males, 7 females, aged 26-61 years) with aortic valve prostheses (AVP). In all pts a titre of anti-myocardial antibodies, a concentration of free-circulating immune complexes and leucocytes migration inhibition test with myocardial antigen were assessed before operation and 1, 12, 24 months after operation. In 20 pts with AH immunological humoral response against HLA antigens was evaluated. After the operation pathological indexes of immunological response against myocardial antigens were observed both in pts with AH as in pts with AVP. The mean titre of anti-myocardial antibodies before operation was in both groups between 1:4 and 1:8, and 1 month after operation between 1:32 and 1:64. In 12 and 24 months after operation the mean titre in AH and AVP group was respectively 1:8 and 1:4. Before operation pathological concentration of immune complexes (> 0.084 mg/ml) was observed in 17% AH and 11% AVP pts. Pathological elevation of immune complexes 1, 12 and 24 months after operation was observed respectively in AH and AVP group in 58%, 42%, 33% and 67%, 50%, 42%. Leucocyte migration inhibition index was pathological (< 0.8) before operation in 58% in both groups, and 1, 12, 24 months after operation was pathological in AH and AVP group respectively in 67%, 17%, 17% and 61%, 33%, 31%. In most pts of both groups immunological response against myocardial antigens was transient and was terminated up to 12-24 months after operation.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Waszyrowski T,Zebrowski A,Krzemińska-Pakuła M,Kaczmarek A,Dziatkowiak A,Sokół Gsubject
Has Abstractpub_date
1993-01-01 00:00:00pages
15-9; discussion 20issue
1eissn
0022-9032issn
1897-4279journal_volume
38pub_type
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pub_type： 杂志文章,评审
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journal_title：Kardiologia polska
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pub_type： 杂志文章
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journal_title：Kardiologia polska
pub_type： 杂志文章
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journal_title：Kardiologia polska
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
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journal_title：Kardiologia polska
pub_type： 杂志文章
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journal_title：Kardiologia polska
pub_type： 杂志文章
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2018.0214
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2010-12-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2007-02-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
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pub_type： 杂志文章,随机对照试验
doi：
更新日期：2008-06-01 00:00:00
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doi：
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journal_title：Kardiologia polska
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doi：
更新日期：2004-12-01 00:00:00
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journal_title：Kardiologia polska
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doi：
更新日期：2004-07-01 00:00:00
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pub_type： 传,历史文章,杂志文章
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doi：10.5603/KP.a2015.0216
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pub_type： 杂志文章,随机对照试验
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journal_title：Kardiologia polska
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doi：
更新日期：2006-07-01 00:00:00
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更新日期：2016-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
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doi：
更新日期：2011-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
