Abstract：
:Atherothrombotic diseases (ATEs) and venous thromboembolism (VTE) have been traditionally considered to have a distinct pathogenesis. Today, a growing body of evidence on the pathophysiology of thrombus formation has convincingly proved that they share more mutual risk factors than previously recognized. It has been shown in a number of case‑control studies that there is a significant risk for a subsequent cardiovascular disease after VTE, although this risk is low or at most moderate. In the past 2 decades, the role of each inherited risk factor for VTE in relation to ATE has been intensively studied. Unfortunately, a large body of contradictory findings has been published that hinders consensus and transformation of knowledge into clinical practice. Complicated gene‑gene interactions, small sample sizes, heterogeneous genetic and environmental patient backgrounds, confounding factors, and varied methodological designs may have contributed to opposing findings. In the case of rare thrombophilias, conclusions must be summarized based on case reports or case series, as only few case‑control and cohort studies are available. In this review we focus on available evidence and controversies regarding the relationship between the classic inherited VTE risk factors (factor V Leiden, prothrombin 20210A, deficiencies of antithrombin, protein C, and protein S) and the risk of myocardial infarction (MI). We conclude that the risk of MI in patients with common inherited thrombophilia is generally modest. However, in patients with deficiencies of antithrombin, protein C, or protein S, the risk of MI or other ATEs is not negligible. A personalized clinical approach is suggested when testing for inherited thrombophilia in a patient with MI.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
Bereczky Z,Balogh L,Bagoly Zdoi
10.33963/KP.14804subject
Has Abstractpub_date
2019-04-18 00:00:00pages
419-429issue
4eissn
0022-9032issn
1897-4279journal_volume
77pub_type
杂志文章,评审abstract：:Selected indices of left and right ventricular function and pulmonary circulation have been compared in two groups of patients with constrictive pericarditis: i.e. in 10 patients classified as NYHA functional class II and 13 patients as NYHA class III. The patients with NYHA class III showed higher average values of l...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：BACKGROUND:Acute myocardial infarction (AMI) causes remodelling of the left ventricle (LV). Restoration of patency of an infarct-related artery by percutaneous coronary interventions (PCI) may prevent or inhibit cardiac remodelling. AIM:To assess LV contractility and function by serial echocardiographic examinations. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2003-11-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2018.0212
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:A case of a 42-year old man with aortic valve endocarditis with peri-anular multi-chamber abscess formation and fistulous communication between right sinus of Valsalva and right ventricle, is presented. Transthoracic echocardiography revealed abnormal flow through the fistula confirmed at surgery. Intraoperatively the...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2019.0041
更新日期：2018-12-20 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0216
更新日期：2016-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15650
更新日期：2021-01-25 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2014.0189
更新日期：2015-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2016.0001
更新日期：2016-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2011-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-03-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2008-05-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.2013.0264
更新日期：2013-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:An individual assessment of global risk of death from cardiovascular diseases (CVD) should guide management, both life style changes and medical therapy, in order to decrease risk factors and improve prognosis. AIM:We assessed global risk in the Polish population and its relation to medical care, including ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-06-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2008-07-01 00:00:00
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journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Precordial maps of R, S and Q waves were performed in 43 children with congenital and acquired cardiac defects, with cardiomyopathies and also in 55 healthy children. Two subgroups with the left and right ventricular hypertrophies were separated basing on a standard electrocardiogram. Multilead electrocardiogram (M60-...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:The value of radioimmunoassay for creatine kinase BB isoenzyme (CK-BB) determination in early diagnosis of acute myocardial infarction was estimated. The clinical material consisted of 35 randomly selected patients admitted to a coronary care unit during the 4 h after chest pain suspected for myocardial infarction. In...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:In 17 patients aged 21-61 (mean 32) with WPW syndrome the transoseophageal stimulation was performed before and after intravenous administration of propranolol (0.1 mg/kg b.w.) and atropine (0.02 mg/kg b.w.). Pharmacological blockade of the autonomic nervous system resulted in statistically significant increase of hea...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：:Churg-Strauss syndrome is a rare systemic disease characterized by necrotising vasculitis and peripheral eosinophilia. Cardiac involvement is found in up to 64% of patients and is given a high rank among the causes of morbidity and mortality. We presented a case of 26 year-old male with Churg-Strauss syndrome and left...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
