Abstract：
:Considerable variation in the use and duration of antiplatelet medications during the perioperative and postoperative care of patients undergoing coronary artery bypass grafting (CABG) reflects the limited number of studies focused directly on these patients as well as the variation in the results reported. In this review we highlight the incidence and mechanisms of graft closure as well as the evidence in support of antiplatelet therapy that is balanced by the impact of antiplatelet therapy on the risk of bleeding to provide recommendations for the use of this therapy in patients undergoing CABG. Low-dose acetylsalicylic acid (ASA; ≤ 160 mg daily) reduces the incidence of perioperative myocardial infarction, acute renal injury, and mortality without increasing the risk of bleeding and so is recommended both before and after CABG. The use of dual antiplatelet therapy with ASA plus a P2Y12 antagonist adds a greater risk of bleeding. While additional studies are required, we can make the following recommendations: because of increased bleeding and mortality when patients are treated with clopidogrel preoperatively, CABG should be delayed for five days. Because of increased bleeding when patients are treated with ticagrelor preoperatively, CABG should be delayed for three days. Because of increased bleeding when patients are treated with prasugrel preopera-tively, CABG should be delayed for seven days. For patients who had a coronary stent placed preoperatively or had an acute coronary syndrome preoperatively, resumption of therapy with their P2Y12 antagonist postoperatively for 12 months reduces the subsequent incidence of cardiovascular events.
journal_name
Kardiol Poljournal_title
Kardiologia polskaauthors
DeStephan CM,Schneider DJdoi
10.5603/KP.a2018.0111subject
Has Abstractpub_date
2018-01-01 00:00:00pages
945-952issue
6eissn
0022-9032issn
1897-4279pii
VM/OJS/KP/12316journal_volume
76pub_type
杂志文章,评审abstract：BACKGROUND:Data from clinical trials suggested that biodegradable-polymer-based drug-eluting stents (DES) might improve long-term clinical outcomes. PROLIM (Balton, Warsaw, Poland) DES is based on a stainless steel platform with a closed cell design releasing sirolimus from biodegradable copolymer (lactic and glycolic ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0208
更新日期：2016-01-01 00:00:00
abstract：:The aim of the study was to investigate the effect of a new selective alpha 1-adrenoreceptor blocker doxazosin on blood pressure, serum lipids and lipoproteins in patients with essential hypertension. The study was done in 32 out-patients with mild-to-moderate hypertension (22 men and 10 women, mean age 45.6 +/- 10.1)...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-02-01 00:00:00
abstract：BACKGROUND:Progress in non-invasive diagnostic techniques such as ultrasonography, computerised tomography or magnetic resonance caused a significant decrease in the use of diagnostic myocardial biopsy (DMB). However, recent advances in molecular biology and widening knowledge about the role of new biochemical markers ...
journal_title：Kardiologia polska
pub_type： 历史文章,杂志文章
doi：
更新日期：2005-04-01 00:00:00
abstract：:The clinical and echocardiographic variables related to spontaneous echo contrast were evaluated in a consecutive series of 600 patients undergoing transesophageal echocardiography with a 5-MHz single plane transducer. The spontaneous contrast was observed in 110 patients (18%). It was seen mainly in the atria; in the...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1993-05-01 00:00:00
abstract：:A case of percutaneous treatment of neonatal critical aortic stenosis is presented. The baby had endocardial fibroelastosis and borderline dimensions of left heart structures. Umbilical access for the anterograde approach with the use of coronary angioplasty catheter was successfully performed. ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Sotalol is a class III antiarrhythmic drug commonly used in various arrhythmia treatments. However, due to its potent potassium channel inhibition, it can prolong the QT interval and lead to malignant arrhythmias. Empagliflozin is an inhibitor of sodium‑glucose cotransporter 2 (SGLT2) and has a positive effe...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.33963/KP.15666
更新日期：2021-01-25 00:00:00
abstract：:Diagnostic approach to and management of SHTG are not always straightforward and specialist knowledge is required, particularly with the expected increase in the rates of SHTG associated with obesity and diabetes epidemics. We hope that this article will prove helpful for physicians caring for such patients. Their man...
journal_title：Kardiologia polska
pub_type： 杂志文章,评审
doi：10.5603/KP.2013.0254
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Efficacy of carotid endarterectomy (CEA) in prevention of stroke in patients with carotid artery stenosis has been confirmed in randomised trials. Carotid artery stenting (CAS) is a routine clinical practice and recent results of CAS are not worse than CEA. Moreover, percutaneous transluminal angioplasty (PT...
journal_title：Kardiologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：:Successful delivery of progenitor cells to the injury zone is a prerequisite for any effect of myocardial regeneration therapy. This key issue, however, has received far less attention than, for instance, a potential need for cell type selection or ex-vivo expansion, the optimal timing of cell application or multimoda...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:Atherothrombotic diseases (ATEs) and venous thromboembolism (VTE) have been traditionally considered to have a distinct pathogenesis. Today, a growing body of evidence on the pathophysiology of thrombus formation has convincingly proved that they share more mutual risk factors than previously recognized. It has been s...
journal_title：Kardiologia polska
pub_type： 杂志文章,评审
doi：10.33963/KP.14804
更新日期：2019-04-18 00:00:00
abstract：:Chronic thromboembolic pulmonary embolism not preceded by clinical thromboembolic event(s) in a 50 year-old male with a history of three-year dyspnea on exertion was detected. Proximal chronic pulmonary embolism, mean pulmonary artery pressure 32 mm Hg, and pulmonary vascular resistance of 444 dyn x s(-1) x cm(-5) wer...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Recent studies have reported the existence of obesity paradox in acute coronary syndromes (ACS). However, the occurrence of obesity paradox in men and women has not yet been thoroughly investigated, even though both genders differ in patterns and incidence of obesity. AIM:Therefore, the aim of this study wa...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0087
更新日期：2015-01-01 00:00:00
abstract：:In the paper computer aided method is described which can be applied for scenario generation of the health care system for cardiovascular diseases treatment. The real life system is represented in the form of patient flows in the network of diagnostic and therapeutic medical services. The adequate computer system with...
journal_title：Kardiologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1989-01-01 00:00:00
abstract：:A case of a 49-year-old female with a history of two myocardial infarctions (MI) and ischaemic stroke is presented. The patient was admitted to the hospital due to a third acute MI. Laboratory investigations revealed resistance to activated protein C due to factor V Leiden mutation. Diagnosis and treatment of patients...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2005-02-01 00:00:00
abstract：BACKGROUND:A Fontan-type operation, i.e. a connection of the systemic veins and pulmonary arteries without subpulmonary ventricle, with different surgical techniques, is nowadays the only treatment option for patients with a functionally univentricular heart (UVH). Understanding the development of pulmonary arteries in...
journal_title：Kardiologia polska
pub_type： 临床试验,杂志文章
doi：10.5603/KP.2013.0121
更新日期：2013-01-01 00:00:00
abstract：:A case of a 29-year-old woman 18 days after delivery with catastrophic antiphospholipid syndrome secondary (CAPS) due to undiagnosed systemic lupus erythematosus, leading to cardiogenic shock is reported. Laboratory evaluation revealed increased anticardiolipin antibodies, lupus anticoagulant, antinuclear antibody and...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:Despite wide popularity of football, there is a paucity of scientific evidence explaining the relationship between being a competitive footballer and life expectancy. AIM:The study analyses and compares cause-specific mortality of Polish male elite footballers and the general Polish male population. METHOD...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2018.0173
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Primary percutaneous coronary intervention (PPCI) is regarded as the treatment of choice for ST elevation myocardial infarction (STEMI) patients. It has been emphasised that only experienced centres with round-the-clock cathlab facilities should perform PPCI. Some investigators have doubted whether PPCI perf...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:A case of a 45-year-old male patient with hypertrophic cardiomyopathy (HCM) is presented. The patient suffered from chest pain since his childhood. He was hospitalised several times but accurate diagnosis was not established for nearly 20 years. The ECG changes were interpreted as myocardial ischaemia. The proper diag...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:In 3 post-MI patients with multiple premature ventricular complexes, programmed transoesophageal pacing generated the arrhythmia and an ecg tracing was taken. Analysis of the ecg suggested that simultaneous activation of two pathways within the A-V node maybe the cause of the arrhythmia. The activation signal reaches ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:The passage of a lead in tissues and in the cardiovascular system depends on the implantation technique. The structure of the leads, which is a combination of two or more materials, triggers their wear. Breakage of the external pacemaker (PM) lead insulation causes unsealing of the lead and exposure of its i...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2014.0108
更新日期：2014-01-01 00:00:00
abstract：:Apelin is a recently discovered biologically active peptide present in several isoforms that are agonists for orphan receptor APJ. Apelin and APJ receptor were found in the central nervous system and in different peripheral tissues. In the cardiovascular system the peptide is present both in the heart and in the endot...
journal_title：Kardiologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Atrial fibrillation (AF) is the most common supraventricular tachyarrhythmia. Percutaneous left atrial appendage occlusion (LAAO) may be considered for stroke prophylaxis in patients with nonvalvular AF (NVAF), especially in contraindications for oral anticoagulants (OAC) or high risk of bleeding. The data a...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2017.0115
更新日期：2017-01-01 00:00:00
abstract：:The study was designed to assess the influences of antiarrhythmic therapy on exercise tolerance in patients with coronary artery disease and ventricular arrhythmias. Subjects for this study were subdivided into 3 groups: group I - 46 patients treated with amiodarone 1,200 mg daily during 10 days and 200-600 mg daily w...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：:Authors analyzed ecg recordings of 112 exercise tests performed in males aged 29-62. 15 precordial leads map (inclusive of V1-V6 standard leads) was used to record ecg tracings. In 22 patients (19.5%) ischemic, electrocardiographic changes were only observed at non-standard leads. Obtained data indicate higher sensiti...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Endothelial dysfunction (ED) may indirectly influence the outcome of patients with coronary artery disease. AIM:To assess the influence of cardiac rehabilitation (CR) on endothelial function in patients after ST-segment elevation myocardial infarction (STEMI). METHODS:Twenty-nine patients scheduled for CR ...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.a2015.0177
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:According to epidemiological studies, dyslipidaemia is the commonest risk factor of atherosclerosis in the Polish population. It is estimated that 18 million adult Poles are affected by dyslipidaemia. AIM:The purpose of this study was to evaluate the quality of the statin therapy in high-risk Polish outpati...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：10.5603/KP.2013.0037
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:The effective antihypertensive therapy is one of the main goals of treatment in metabolic syndrome (MS) because hypertensive patients with MS are of high cardiovascular risk. The impedance cardiography (ICG), as a modern technique of non-invasive haemodynamic monitoring, enables the evaluation of cardiac ind...
journal_title：Kardiologia polska
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2012-01-01 00:00:00
abstract：:Churg-Strauss syndrome is a rare systemic disease characterized by necrotising vasculitis and peripheral eosinophilia. Cardiac involvement is found in up to 64% of patients and is given a high rank among the causes of morbidity and mortality. We presented a case of 26 year-old male with Churg-Strauss syndrome and left...
journal_title：Kardiologia polska
pub_type： 杂志文章
doi：
更新日期：2010-07-01 00:00:00
abstract：:Despite continuous progress in pharmacological management and development of myocardial revascularisation techniques, a significant number of patients with advanced ischemic heart disease and refractory angina pectoris cannot be treated successfully. For the group of patients with chronic refractory angina therapeutic...
journal_title：Kardiologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2010-12-01 00:00:00
