Abstract:
:Background. Colon capsule endoscopy (CCE) is a diagnostic test with relatively rare usage. In this study, we aimed to evaluate both the optimal cleaning regimen for CCE and the diagnostic value of test in the study group. Methods. A total of 62 patients were enrolled in this study. In the first step, 3 different colon preparing regimens were given to 30 patients [Group A: 3 days of liquid diet, sodium phosphate (NaP) (90 mL), and NaP enema; Group B: 3 days of liquid diet, 4 L of polyethylene glycol (PEG), and metoclopramide; Group C: 3 days of liquid diet, 4 L of PEG, NaP (45 mL), and bisacodyl after capsule ingestion] (10 patients in each group). The other consecutive 32 patients were cleaned with the best regimen which was NaP + PEG and CCE was performed. The results of CCE were controlled with colonoscopy in 28 patients. Results. Group C had the highest cleaning score, compared with the other groups (2.2 ± 0.4 versus 2.7 ± 0.4 versus 3.7 ± 0.4, p value = 0.000). The CCE findings were as follows in 28 patients who were also examined with colonoscopy: polyp (range: 5-10 mm) in 6 patients, internal hemorrhoids in 3 patients, angiodysplasia in 1 patient, diverticula in 1 patient, and ulcerative colitis in 1 patient. The sensitivity, specificity, PPV, and NPV of CCE were 100%, 92%, 93%, and 100%, respectively. Conclusions. Low dosage NaP combined with PEG provides optimal bowel preparation for CCE. CCE appears to be a highly sensitive diagnostic modality for detecting colonic pathologies.
journal_name
Gastroenterol Res Practjournal_title
Gastroenterology research and practiceauthors
Akyüz Ü,Yılmaz Y,İnce AT,Kaya B,Pata Cdoi
10.1155/2016/2738208subject
Has Abstractpub_date
2016-01-01 00:00:00pages
2738208eissn
1687-6121issn
1687-630Xjournal_volume
2016pub_type
杂志文章abstract::Pancreatic adenocarcinoma is an aggressive disease that has poor outcomes despite maximal traditional therapies. Thus, treatment of this cancer demands innovative strategies to be used in addition to standing therapies in order to provide new avenues of care. Here, we describe the technique of using endoscopic ultraso...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2013/207129
更新日期:2013-01-01 00:00:00
abstract:Objectives:The incidence of gastrointestinal stromal tumors (GISTs) located in the colon is rare. Current studies mainly focus on case reports for colonic GISTs. Therefore, a population-based analysis was useful to guide the clinical treatment strategy. Methods:The patients were selected from 2000 to 2015 based on Sur...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2019/3849850
更新日期:2019-04-11 00:00:00
abstract::Background and Aims. Although the differential expression of microRNA (miRNA) genes has been identified in many diseases, little information exists concerning the miRNA expression profile in type 2 diabetes mellitus (T2DM) with diarrhea-predominant irritable bowel syndrome (D-IBS). Therefore, the specific expression o...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/9256209
更新日期:2016-01-01 00:00:00
abstract::Survival rates among HIV patients have significantly improved since the introduction of antiretroviral therapy (ART) in HIV management. However, persistent disease progression and clinical complications in virally suppressed individuals point to additional contributing factors other than HIV replication; microbial tra...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2014/803185
更新日期:2014-01-01 00:00:00
abstract::Clostridium difficile toxin A is a colonic inflammatory agent that acts partially by activation of TRPV1 (transient receptor potential vanilloid type 1). Resiniferatoxin (RTX) is an excitotoxin that activates TRPV1 at low concentrations and defunctionalizes TRPV1 at high concentrations. RTX at various doses was inject...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/8438172
更新日期:2017-01-01 00:00:00
abstract::Background and Aims. The study was a repeated evaluation of the experience of capsule endoscopy (CE) in patients with cardiac pacemaker or implantable cardioverter defibrillator (ICD). Patients and Methods. A standardized questionnaire was sent by the manufactors Given Imaging and Olympus to all centers in Germany, Au...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/717408
更新日期:2012-01-01 00:00:00
abstract::Perioperative chemotherapy improves overall survival in patients with oesophagogastric adenocarcinoma (OAC) and locoregional disease. The mainstay of perioperative chemotherapy in these patients is a platinum/fluoropyrimidine combination. The phase III FLOT4 trial has shown that the FLOT triplet regimen (oxaliplatin, ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2017/5651903
更新日期:2017-01-01 00:00:00
abstract::Background. There is increasing evidence suggesting that the laparoscopic technique is the treatment of choice for large bowel resection, including for malignancy. The purpose of the study was to assess whether general surgeons, with particular skills in advanced laparoscopy, can adequately provide safe laparoscopic c...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/581523
更新日期:2014-01-01 00:00:00
abstract::Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high rate of mortality and poor prognosis. Numerous studies have proved that microRNA (miRNA) may play a vital role in a wide range of malignancies, including PDAC, and dysregulated miRNAs, including circulating miRNAs, are associated with PDAC...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2014/386561
更新日期:2014-01-01 00:00:00
abstract::The incidence of inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis (UC), has increased in pediatric populations over the last decade. Patients diagnosed during childhood often survive well into adulthood, and therefore their healthcare requires transfer to an adult gastroenterolo...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2015/853530
更新日期:2015-01-01 00:00:00
abstract::Reorganization of the actin cytoskeleton underlies cell migration in a wide variety of physiological and pathological processes, such as embryonic development, wound healing, and tumor cell invasion. It has been shown that actin assembly and disassembly are precisely regulated by intracellular signaling cascades that ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2015/930157
更新日期:2015-01-01 00:00:00
abstract::Introduction. In a previously published article the authors reported the long-term follow-up results in 138 consecutive patients with gallstones and common bile duct (CBD) stones who underwent laparoscopic transverse choledochotomy (TC) with T-tube biliary drainage and laparoscopic cholecystectomy (LC). Aim of this st...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/9506406
更新日期:2016-01-01 00:00:00
abstract::Aims. We here investigated whether the combination of simvastatin and irinotecan could induce the synergistic effect on colon cancer cells with or without resistance to irinotecan. Methods. We investigated cell proliferation assay and assessed cell death detection ELISA and caspase-3 activity assay of various concentr...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/7891374
更新日期:2016-01-01 00:00:00
abstract:Background:Prokinetic agents are used in diabetic gastroparesis patients to improve gastric emptying and upper gastrointestinal (GI) symptoms. However, the efficacy of prokinetic agents against glycemic control is questionable. Therefore, we conducted a systemic review and meta-analysis to determine the efficacy of pro...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2019/3014973
更新日期:2019-09-09 00:00:00
abstract:Background:The objective of this study was to determine the factors associated with severity of acute pancreatitis (AP) according to two major etiologies: alcohol and gallstones. Methods:We reviewed the medical records of consecutive patients who were admitted with AP between January 2003 and January 2013. A total of ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/1219464
更新日期:2017-01-01 00:00:00
abstract:Background:Baicalin (BA) has been shown to have anti-inflammatory and antioxidant activity. Zinc is a nutrient element. Objective:This study is aimed at investigating the antichronic gastric ulcer activity of Zn-Baicalin complex (BA-Zn) and its related mechanisms in an acetic acid-induced gastric ulcer rat model. Res...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/1275486
更新日期:2018-10-28 00:00:00
abstract::Endoscopic retrograde cholangiopancreatography (ERCP) can fail in 3-10% of the cases even in experienced hands. Although percutaneous transhepatic cholangiography (PTC) and surgery are the traditional alternatives, there are morbidity and mortality associated with both. In this paper, we have discussed the efficacy an...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2013/869214
更新日期:2013-01-01 00:00:00
abstract::Purpose. In the present study, the prognostic significance of CpG island methylator phenotype (CIMP) in stage II/III sporadic colorectal cancer was evaluated using a five-gene panel. Methods. Fifty stage II/III colorectal cancer patients who received radical resection were included in this study. Promoter methylation ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/436985
更新日期:2014-01-01 00:00:00
abstract::Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postcon...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/2604032
更新日期:2016-01-01 00:00:00
abstract::Caustic esophageal stricture (CES) in children still occurs frequently in developing countries. We aimed to evaluate the long-term outcomes of endoscopic balloon dilatation (EBD) in treating CES in children and the influencing factors associated with outcome. We retrospectively reviewed the data of all patients who ha...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/8352756
更新日期:2018-08-08 00:00:00
abstract::Background. Transanal irrigation (TAI) can successfully treat neurogenic bowel dysfunction (NBD), but patient perception of its use in chronic idiopathic constipation (CIC) is unknown. Objective. To evaluate patient perceptions of the efficacy and safety of TAI for CIC and whether there are predictive factors of perce...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/3826087
更新日期:2017-01-01 00:00:00
abstract:Objective:Fucosterol is derived from the brown alga Eisenia bicyclis and has various biological activities, including antioxidant, anticancer, and antidiabetic properties. The aim of this study was to investigate the protective effects of fucosterol pretreatment on Concanavalin A- (ConA-) induced acute liver injury in ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/2824139
更新日期:2018-07-17 00:00:00
abstract::The most common cause of chronic pancreatitis (CP) is alcohol abuse. The aim of the present study was to identify patients with genetic predisposition to CP abusing alcohol. The question posed was whether CP manifests at a younger age and diabetes mellitus develops earlier in individuals with genetic predisposition. T...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2015/309156
更新日期:2015-01-01 00:00:00
abstract::Although the thread-traction (TT) method has been found useful during endoscopic submucosal dissection (ESD) for early gastric cancers, the movement of the thread interferes with the movement of the endoscope, and the lesion can only be pulled to the mouth side. We have developed the novel TT method using a sheath of ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/9415497
更新日期:2016-01-01 00:00:00
abstract::Background/Aims. This study aimed to establish optimal propofol anesthesia for therapeutic endoscopy, which has not been established. Methodology. We retrospectively investigated data on 89 patients who underwent upper-GI endoscopic submucosal dissection or endoscopic mucosal resection under anesthesia with propofol. ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2015/282149
更新日期:2015-01-01 00:00:00
abstract:Aim:Monocytes play an important role in acute pancreatitis (AP). Hypertriglyceridemic pancreatitis (HTGP) is always more severe than normal lipid-AP, whether the mechanism of aggravation involves monocyte subsets remains unknown though. The present study was aimed to analyze changes of peripheral blood M1 and M2 monocy...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2019/5705782
更新日期:2019-06-10 00:00:00
abstract:Background/Objectives:This meta-analysis is aimed at investigating the prognostic roles of the inflammatory markers neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in patients with pancreatic cancer. Methods:The correlations between high inflammatory marker expression levels and prognosis i...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/9745601
更新日期:2018-06-07 00:00:00
abstract::This study was aimed at investigating the effect of baicalin on experimental cholesterol gallstones in mice. The mouse gallstone model was induced by feeding with a lithogenic diet, and cholesterol stones were found in the gallbladder. The lithogenic diet caused elevation of triglycerides, cholesterol, and low-density...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2020/1343969
更新日期:2020-04-21 00:00:00
abstract::Objective. In the present study, since PON1 is known as an HDL-associated antioxidant enzyme that inhibits the oxidative modification of LDL and oxidative stress plays a role in the pathogenesis of mesenteric ischemia, we investigated the changes in PON1 activity and lipid profile in an experimental ischemic colitis m...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/979506
更新日期:2012-01-01 00:00:00
abstract::Background. Helicobacter pylori chronically colonizes gastric/duodenal mucosa and induces gastroduodenal disease and vigorous humoral and cellular immune responses. Methods. In order to clarify the immunological changes induced by this infection, we determined the percentage and, as indicated, ratios of the following ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/819842
更新日期:2012-01-01 00:00:00