Local and Remote Postconditioning Decrease Intestinal Injury in a Rabbit Ischemia/Reperfusion Model.

Abstract:

:Intestinal ischemia/reperfusion (I/R) injury is a significant problem that is associated with high morbidity and mortality in critical settings. This injury may be ameliorated using postconditioning protocol. In our study, we created a rabbit intestinal I/R injury model to analyze the effects of local ischemia postconditioning (LIPo) and remote ischemia postconditioning (RIPo) on intestinal I/R injury. We concluded that LIPo affords protection in intestinal I/R injury in a comparable fashion with RIPo by decreasing oxidative stress, neutrophil activation, and apoptosis.

authors

Yang M,Dong JX,Li LB,Che HJ,Yong J,Song FB,Wang T,Zhang JW

doi

10.1155/2016/2604032

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

2604032

eissn

1687-6121

issn

1687-630X

journal_volume

2016

pub_type

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