Impact of Astrocytes on the Injury Induced by In Vitro Ischemia.

abstract：:The sympathoneural and the adrenomedullary systems are involved in regulation of immune processes. Their impairment has been suggested in patients with rheumatoid arthritis (RA). In this study, sympathetic response to orthostasis was evaluated in 22 RA females with <40 years of age and in 15 matched healthy controls. ...

journal_title：Cellular and molecular neurobiology

authors： Vlcek M,Rovensky J,Eisenhofer G,Radikova Z,Penesova A,Kerlik J,Imrich R

更新日期：2012-07-01 00:00:00

abstract：:1. Antidepressants have been used clinically for many years; however, the neurochemical mechanism for their therapeutic effect has not been clarified yet. Recent reports indicate that chronic antidepressant treatment directly affects the postsynaptic membrane to increase the coupling between the stimulatory GTP-bindin...

journal_title：Cellular and molecular neurobiology

authors： Kamada H,Saito T,Hatta S,Toki S,Ozawa H,Watanabe M,Takahata N

更新日期：1999-02-01 00:00:00

abstract：:Acute injury of central nervous system (CNS) starts a cascade of morphological, molecular, and functional changes including formation of a fibrotic scar, expression of transforming growth factor beta 1 (TGF-β1), and expression of extracellular matrix proteins leading to arrested neurite outgrowth and failed regenerati...

journal_title：Cellular and molecular neurobiology

authors： Ondáčová K,Jurkovičová D,Lacinová Ľ

更新日期：2017-07-01 00:00:00

abstract：:1. Photoreceptor terminals in the flies Musca domestica and Drosophila melanogaster have been reconstructed in three dimensions from serial EM to reveal the surface distributions of afferent tetrad synapses. 2. The terminals are cylindrical and surround two target cells; they have synaptic sites distributed along thei...

journal_title：Cellular and molecular neurobiology

authors： Meinertzhagen IA,Hu X

更新日期：1996-12-01 00:00:00

abstract：:Hemorrhagic transformation (HT) is a common complication after thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) in ischemic stroke. In this article, recent research progress of HT in vivo and in vitro studies was reviewed. We have discussed new potential mechanisms and possible experimental mode...

journal_title：Cellular and molecular neurobiology

authors： Liu C,Xie J,Sun S,Li H,Li T,Jiang C,Chen X,Wang J,Le A,Wang J,Li Z,Wang J,Wang W

更新日期：2020-10-30 00:00:00

abstract：:Sulfur dioxide (SO2) is a common gas pollutant that is detrimental to many organs. Previous studies have shown that SO2 exposure is involved in neurotoxicity and increased risk of many brain disorders; however, our understanding of the mechanisms underlying SO2-induced cytotoxicity on neuronal cells remains elusive. T...

journal_title：Cellular and molecular neurobiology

authors： Guan DF,Ren PY,Hu W,Zhang YL

更新日期：2015-05-01 00:00:00

abstract：:The effects of the calcium channel blocker D-600 on the cation channels activated by acetylcholine (ACh) was studied in voltage-clamped Aplysia neurons by voltage-jump relaxation analysis. D-600 blocked the steady-state ACh current in a highly voltage-dependent manner, the degree of antagonism increasing with membrane...

journal_title：Cellular and molecular neurobiology

authors： Slater NT,Haas HL,Carpenter DO

更新日期：1983-12-01 00:00:00

abstract：:Naked2 (NKD2), one member of Naked family, has been shown to negatively regulate Wnt/β-catenin signaling pathway. It has been recognized that NKD2 plays a vital role in cell homeostasis and prevention of tumorigenesis. However, NKD2 expression and its functional role in the brain in neuroinflammatory processes remain ...

journal_title：Cellular and molecular neurobiology

authors： Cui Z,Zhou L,Song Y,Liu C,Zhu G,Wu X,Yan Y,Xia X,Duan C,Zhou Y,Huang Y,Zhang D

更新日期：2016-01-01 00:00:00

abstract：:Traumatic brain injury (TBI) is a leading cause of death and long-term disability. Fucoidan, a sulfated polysaccharide extracted from brown algae, possesses potent anti-oxidative and anti-inflammatory effects. Considering TBI happens frequently in adults, especially in aged individuals, we herein sought to define the ...

journal_title：Cellular and molecular neurobiology

authors： Wang T,Zhu M,He ZZ

更新日期：2016-11-01 00:00:00

abstract：:Endothelins regulate cellular functions in the mammalian brain through the endothelin receptors A and B (EDNRA and EDNRB). In this study, we investigated the role of EDNRB on cell proliferation in the cerebellum by using the spotting lethal (sl) rat, which carries a naturally occurring deletion in the EDNRB gene. Prol...

journal_title：Cellular and molecular neurobiology

authors： Vidovic M,Chen MM,Lu QY,Kalloniatis KF,Martin BM,Tan AH,Lynch C,Croaker GD,Cass DT,Song ZM

更新日期：2008-12-01 00:00:00

abstract：:Depression is a major psychiatric disorder affecting nearly 21% of the world population and imposes a substantial health burden on society. Although significant progress has been made in depression research, the common molecular mechanism of antidepressants is still far from clearly understood. The neuroprotective eff...

journal_title：Cellular and molecular neurobiology

authors： Zheng M,Liu C,Pan F,Shi D,Ma F,Zhang Y,Zhang Y

更新日期：2011-04-01 00:00:00

abstract：:We have previously demonstrated that alpha2-adrenoceptors regulate hypothalamic magnocellular oxytocinergic (OXY) neurons in Sprague Dawley rats. Here we investigated whether activation/inhibition of alpha2-adrenoceptors may similarly trigger/downregulate the activity of OXY neurons in control Long Evans (+/+) and per...

journal_title：Cellular and molecular neurobiology

authors： Bundzikova J,Pirnik Z,Zelena D,Mikkelsen JD,Kiss A

更新日期：2009-09-01 00:00:00

abstract：:In rats, variations in the levels of neuromodulatory molecules and in the expression of their receptors are observed during pregnancy and postpartum. These changes may contribute to the development and management of maternal behavior. The frequency of licking the pups is used to evaluate maternal care, having mothers ...

journal_title：Cellular and molecular neurobiology

authors： de Moura AC,da Silva IR,Reinaldo G,Dani C,Elsner VR,Giovenardi M

更新日期：2016-10-01 00:00:00

abstract：:1. Chitin is known to promote skin wound healing. In this study, chitin, prepared from Zuwai crab shell, was used as a bridge between the proximal and distal stumps of cut hypoglossal nerves in shrews. We compared the effects of chitin on the regeneration of transected right hypoglossal nerve axons, with those of porc...

journal_title：Cellular and molecular neurobiology

authors： Itoh M,Izumi S,Uemura M,Baba N,Suyama K,Kuga Y,Mizuno A,Nakane PK,Koji T

更新日期：2000-10-01 00:00:00

abstract：:1. Several intrinsically disordered proteins (IDPs) play principal role in the neurodegenerative processes of various types. Among them, alpha-synuclein is involved in Parkinson's disease, prion protein in transmissible spongiform encephalopathies, and tau protein in Alzheimer's disease (AD) and related tauopathies. N...

journal_title：Cellular and molecular neurobiology

authors： Skrabana R,Sevcik J,Novak M

更新日期：2006-10-01 00:00:00

abstract：:Acute encephalopathy is a generic term for acute brain dysfunction occurring after infection. Acute encephalopathy induced by influenza virus results in high mortality, and most cases of influenza-associated encephalopathy (IAE) result in brain edema. Administration of diclofenac sodium (DCF), a non-steroidal anti-inf...

journal_title：Cellular and molecular neurobiology

authors： Asai H,Kakita H,Aoyama M,Nagaya Y,Saitoh S,Asai K

更新日期：2013-04-01 00:00:00

abstract：:Consisting of a fragment of ACTH(4-7) and C-terminal PGP tripeptide, the polypeptide Semax is successfully used for acute stroke therapy. Previous experiments showed rapid induction of Bdnf, Ngf, and TrkB expression in intact rat hippocampus following Semax treatment. To investigate the mRNA expression of neurotrophin...

journal_title：Cellular and molecular neurobiology

authors： Dmitrieva VG,Povarova OV,Skvortsova VI,Limborska SA,Myasoedov NF,Dergunova LV

更新日期：2010-01-01 00:00:00

abstract：:1. We have devised a radioimmunoassay for atrial natriueretic factor (ANF). Its application to rat brain extract led to the discovery of ANF in the brain. In addition to the hypothalamus and the pontine medullary region, it was widely distributed. 2. ANF in the brain is stored in a low molecular weight form, in contra...

journal_title：Cellular and molecular neurobiology

authors： Inagami T,Tanaka I,McKenzie JC,Nakamaru M,Takayanagi R,Imada T,Pochet R,Resibois A,Naruse M,Naruse K

更新日期：1989-03-01 00:00:00

abstract：AIM:Poly (ADP-ribose) polymerase (PARP) is a nuclear repair enzyme whose role is widely depicted in various physiological and pathological processes. In the present study, we wanted to check the status of PARP and the role of various cell death proteases involved in apoptotic and non-apoptotic forms of cell death durin...

journal_title：Cellular and molecular neurobiology

authors： Chaitanya GV,Babu PP

更新日期：2009-06-01 00:00:00

abstract：:1. Tau, which is a microtubule-associated protein, with mRNA targeted to the axon and growth cone, is involved in axonal elongation. During postnatal development in mouse, Tau expression in cerebellar granule cells is reduced afte the second postnatal week. The aim of this work was to study the regulation of the rate ...

journal_title：Cellular and molecular neurobiology

authors： Vilá-Ortiz GJ,Santa-Coloma TA,Carminatti H,Radrizzani M

更新日期：2001-10-01 00:00:00

abstract：:1. The retinoblastoma susceptibility gene product, p105Rb (RB), is an important regulator in the control of cell proliferation, differentiation, and apoptosis. Several cellular factors that complex with RB and exert their cellular regulatory functions have been identified, such as the RB:cyclophilin A (CypA) complex. ...

journal_title：Cellular and molecular neurobiology

authors： Chiu R,Rey O,Zheng JQ,Twiss JL,Song J,Pang S,Yokoyama KK

更新日期：2003-12-01 00:00:00

abstract：:Parkinson's disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by the selective loss of nigrostriatal dopaminergic neurons. However, the molecular pathways leading to the dopaminergic neuron degeneration have remained obscure until recently. Reports demonstrated that reduction of b...

journal_title：Cellular and molecular neurobiology

authors： Yuan Y,Sun J,Zhao M,Hu J,Wang X,Du G,Chen NH

更新日期：2010-08-01 00:00:00

abstract：:1. In this study we investigated the effect of 7-nitroindazole (7-NI), a preferential inhibitor of neuronal nitric oxide synthase (nNOS), on kainic acid (KA) induced neurotoxicity in rats. Choline acetyltransferase activity (CAT), a cholinergic marker, and histological changes were employed to assess neurotoxicity. 2....

journal_title：Cellular and molecular neurobiology

authors： Guevara BH,Cespedes GC,Cubeddu LX

更新日期：2002-12-01 00:00:00

abstract：:1. Calcium binding properties were examined in VAT-1, an abundant 41-kDa membrane protein expressed in the cholinergic cynaptic vesicles of Torpedo. 2. An overlay assay, using 45Ca2+ as a tracer, demonstrated the ability of a recombinant VAT-1 produced from the IPTG-inducible pKK223-3 expression vector to bind calcium...

journal_title：Cellular and molecular neurobiology

authors： Levius O,Linial M

更新日期：1993-10-01 00:00:00

abstract：:In our previous research, the formation and development of age-related cataract (ARC) is associated with DNA hypermethylation of some genes in lens epithelial cells (LECs). This study aimed to investigate the expression profile of DNA methylation- and transcriptional repression-associated genes in LECs of ARC. The exp...

journal_title：Cellular and molecular neurobiology

authors： Wang Y,Zhang G,Kang L,Guan H

更新日期：2017-04-01 00:00:00

abstract：:1. Coexisting with oxytocin or vasopressin in the cell bodies and nerve terminals of the hypothalamic-neurohypophysial system are smaller amounts of other peptides. For a number of these "copeptides" there is strong evidence of corelease with the major magnocellular hormones. Guided by the location of their specific r...

journal_title：Cellular and molecular neurobiology

authors： Bondy CA,Whitnall MH,Brady LS,Gainer H

更新日期：1989-12-01 00:00:00

abstract：:The contribution of axonal activity to the ionic currents which generate bursting pacemaker activity was studied by using the two-electrode voltage-clamp technique in Aplysia bursting neuron somata in conjunction with intraaxonal voltage recordings. Depolarizing voltage-clamp pulses applied to bursting cell somata tri...

journal_title：Cellular and molecular neurobiology

authors： Kramer RH

更新日期：1986-09-01 00:00:00

abstract：:Overexpression of suppressor of cytokine signalling 2 (SOCS2) has been shown to promote hippocampal neurogenesis in vivo and promote neurite outgrowth of neurons in vitro. In the adult mouse brain, SOCS2 is most highly expressed in the hippocampal CA3 region and at lower levels in the dentate gyrus, an expression patt...

journal_title：Cellular and molecular neurobiology

authors： Basrai HS,Turbic A,Christie KJ,Turnley AM

更新日期：2017-07-01 00:00:00

abstract：:Available treatment for Parkinson's disease (PD) is mainly symptomatic instead of halting or reversing degenerative processes affecting the disease. Research on the molecular pathogenesis of PD has suggested reduced trophic support as a possible cause or mediator of neurodegeneration. In animal models of the disease, ...

journal_title：Cellular and molecular neurobiology

authors： Gyárfás T,Knuuttila J,Lindholm P,Rantamäki T,Castrén E

更新日期：2010-04-01 00:00:00

abstract：:1. The aim of the present study is to map the incipient phase of Fos expression in the sacral spinal cord neuronal pools of multiple cauda equina constrictions canine model. 2. Fos-positive neurons were found bilaterally in the lateral portion of superficial dorsal horn layers (Laminae I-III) and along the lateral edg...

journal_title：Cellular and molecular neurobiology

authors： Orendácová J,Marsala M,Cízková D,Kafka J,Raceková E,Sulla I,Vanický I,Marsala J

更新日期：2001-08-01 00:00:00