Abstract:
:1. The aim of the present study is to map the incipient phase of Fos expression in the sacral spinal cord neuronal pools of multiple cauda equina constrictions canine model. 2. Fos-positive neurons were found bilaterally in the lateral portion of superficial dorsal horn layers (Laminae I-III) and along the lateral edge of the dorsal horn accompanied by the lateral collateral pathway, fibers of Lissauer's tract, terminating at the sacral parasympathetic nucleus. Similarly, high Fos expression was detected in the ventral portion of the dorsal sacral commissure and in the dorsomedial portion of the anterior horns at S1-S3 segment level. Finally, a clearly expressed Fos-positivity was disclosed bilaterally in the neuropil of the nucleus Y in the anterior horn. 3. Data from the present study show that continuous stimulation of the central fibers of sacral dorsal root ganglia neurons, i.e., fibers of sacral primary afferents, unlike those using various stimulations of the peripheral fibres offers an unusual pattern of Fos-like immunoreactivity.
journal_name
Cell Mol Neurobioljournal_title
Cellular and molecular neurobiologyauthors
Orendácová J,Marsala M,Cízková D,Kafka J,Raceková E,Sulla I,Vanický I,Marsala Jdoi
10.1023/a:1012610407025subject
Has Abstractpub_date
2001-08-01 00:00:00pages
413-9issue
4eissn
0272-4340issn
1573-6830journal_volume
21pub_type
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