Abstract:
BACKGROUND:Acute renal infarction (ARI) is a rare disease. ARI causes decline in renal function in both the acute and chronic phases. However, the correlation between the volume of the infarction and degree of renal function decline has not been fully investigated. Therefore, we aimed to examine the relationship between the volume of the infarction and degree of renal function decline. METHODS:We performed a single-center, retrospective, observational study investigating clinical parameters and the volume of the infarction. The volume of the infarction was measured using reconstructed computed tomography data. RESULTS:A total of 39 patients (mean age, 72.6 ± 13.2 years; men, 59%) were enrolled. The median infarction volume was 45 mL (interquartile range, 14-91 mL). The volume of the infarction was significantly associated with the peak lactate dehydrogenase (LDH) level (median, 728 IU/L; interquartile range, 491-1227 U/L) (r = 0.58, p < 0.01) and the degree of renal function decline in both acute and chronic phases (r = -0.44, -0.38, respectively, p < 0.05). The peak LDH level was significantly correlated with the degree of renal function decline in the acute phase but not in the chronic phase (r = -0.35, -0.21; p < 0.05, N.S., respectively). CONCLUSIONS:The volume of the infarction may be a factor in the degree of renal function decline in ARI. Therefore, assessment of infarct volume in ARI is important.
journal_name
Clin Exp Nephroljournal_title
Clinical and experimental nephrologyauthors
Kagaya S,Yoshie O,Fukami H,Sato H,Saito A,Takeuchi Y,Matsuda K,Nagasawa Tdoi
10.1007/s10157-017-1399-4subject
Has Abstractpub_date
2017-12-01 00:00:00pages
1030-1034issue
6eissn
1342-1751issn
1437-7799pii
10.1007/s10157-017-1399-4journal_volume
21pub_type
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