Female urinary microbiota.

Abstract:

PURPOSE OF REVIEW:The newly discovered female urinary microbiota has the potential to deepen our understanding of urinary tract health and disease, including common lower urinary tract conditions such as urinary incontinence and urinary tract infection. The spectrum of painful bladder disorders and other less common conditions also may benefit from additional research that includes consideration of the resident bacterial community of the female bladder. The present review provides a clinical context for the rapidly emerging research regarding the female urinary microbiota and its relationships with urinary tract conditions of interest. RECENT FINDINGS:Studies using culture-independent techniques confirm prior reports of bacteria that reside in the female urinary bladder. These resident communities, the female urinary microbiota, possess characteristics that differ between women affected by urgency urinary incontinence and matched, unaffected controls. Enhanced urine culture techniques permit cultivation of organisms, including uropathogens, missed by standard urine culture, but detected by culture-independent sequencing techniques. SUMMARY:New technology is available. Clinical laboratories can modify traditional standard urine culture methods to enhance detection of uropathogens. However, given the existence of the female urinary microbiota, the simple presence of bacteria in the lower urinary tract should not be taken as evidence of infection.

journal_name

Curr Opin Urol

authors

Mueller ER,Wolfe AJ,Brubaker L

doi

10.1097/MOU.0000000000000396

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

282-286

issue

3

eissn

0963-0643

issn

1473-6586

journal_volume

27

pub_type

杂志文章,评审
  • Benign prostatic hyperplasia progression and its impact on treatment.

    abstract:PURPOSE OF REVIEW:Management of men with benign prostatic hyperplasia should reduce the lifetime risk of acute urinary retention and the need for benign prostatic hyperplasia-related surgery. A number of recent studies demonstrate that 5alpha-reductase inhibitors are unique in providing a long-term combination of impro...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200401000-00010

    authors: Djavan B,Waldert M,Ghawidel C,Marberger M

    更新日期:2004-01-01 00:00:00

  • The devastated bladder outlet: treatment options.

    abstract:PURPOSE OF REVIEW:The purpose of this study is to review and discuss recently published studies of therapeutic options in cases with the combination of severe sphincteric damage and recurrent stricture of the bladder neck or anastomosis in patients with postradical prostatectomy. RECENT FINDINGS:Recent focus has been ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000185

    authors: Riedmiller H,Kocot A

    更新日期:2015-07-01 00:00:00

  • New diagnostic strategies in the detection and staging of bladder cancer.

    abstract:PURPOSE OF REVIEW:Bladder cancer is a very frequent disease and represents the second most common genitourinary neoplasm. The most prevalent form of the disease, superficial bladder cancer, can recur in more than 70% of cases, despite correct management. Any way to improve our disease diagnostic and treatment policy is...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200309000-00001

    authors: Jichlinski P

    更新日期:2003-09-01 00:00:00

  • Novel imaging techniques reshape the landscape in high-risk prostate cancers.

    abstract:PURPOSE OF REVIEW:High-risk prostate cancers (PCa), that is, those with prostate-specific antigen greater than 20 ng/dl, Gleason Score of at least 8, or extraprostatic spread, are nowadays commonly treated by surgery and radiotherapy combined with a fixed period of systemic treatment. Implementing these strategies requ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e328361d451

    authors: Lecouvet FE,Lhommel R,Pasoglou V,Larbi A,Jamar F,Tombal B

    更新日期:2013-07-01 00:00:00

  • Novel targeted therapy for advanced renal carcinoma: trials in progress.

    abstract:PURPOSE OF REVIEW:Better understanding of renal cell carcinoma biology has led to a new era of targeted therapy in the management of metastatic renal cell carcinoma. This review provides an updated survey of the recently reported and ongoing clinical trials that will help to further define the role of these novel drugs...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32833c86f8

    authors: Calabrò F,Sternberg CN

    更新日期:2010-09-01 00:00:00

  • How to diagnose and treat focal therapy failure and recurrence?

    abstract:PURPOSE OF REVIEW:Focal therapy presents an alternative option for disease-targeted therapy while preserving erectile and urinary function without compromising oncological outcome. Such treatment, which preserves normal prostate parenchyma, presents a clinical challenge to the urologist, as typical disease surveillance...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000052

    authors: Barret E,Harvey-Bryan KA,Sanchez-Salas R,Rozet F,Galiano M,Cathelineau X

    更新日期:2014-05-01 00:00:00

  • Medical treatment of urinary stones.

    abstract:PURPOSE OF REVIEW:To identify the latest progression on medical treatment of urinary stones. RECENT FINDINGS:Nonsteroidal anti-inflammatory drugs should be the preferred analgesic option for patients presenting to the emergency department with renal colic. A-blockers could be of patient benefit when used for distal ur...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000523

    authors: Skolarikos A

    更新日期:2018-09-01 00:00:00

  • How are we going to train a generation of radiologists (and urologists) to read prostate MRI?

    abstract:PURPOSE OF REVIEW:Multiparametric MRI has gained tremendous importance in the daily practice for patients at risk or diagnosed with prostate cancer. Interpretation of multiparametric-MRI is a complex task, supposedly restricted to experienced radiologists. The purpose of this review is to analyze fundamentals of multip...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000217

    authors: Puech P,Randazzo M,Ouzzane A,Gaillard V,Rastinehad A,Lemaitre L,Villers A

    更新日期:2015-11-01 00:00:00

  • The prognostic value of hematological and systemic inflammatory disorders in invasive bladder cancer.

    abstract:PURPOSE OF REVIEW:In contrast to the large amount of evidence reporting on the oncological significance of various clinicopathological and molecular parameters for survival in invasive bladder cancer, alterations of preoperative hematological and systemic inflammatory parameters have not been sufficiently addressed in ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32834966fa

    authors: Gakis G,Todenhöfer T,Stenzl A

    更新日期:2011-09-01 00:00:00

  • Diagnosis of localized prostate cancer: 10 years of progress.

    abstract::Advances in the diagnosis of early stage disease, and particularly the introduction of prostate-specific antigen (PSA) testing, have had a dramatic effect on the presentation and clinical management of prostate cancer during the past ten years. As a result, there have been significant epidemiological changes in countr...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200007000-00006

    authors: Feneley MR,Partin AW

    更新日期:2000-07-01 00:00:00

  • Penile cancer: review of the recent literature.

    abstract:PURPOSE OF REVIEW:To review recent developments in the diagnosis and treatment of penile cancer, we reviewed the medical literature from 1 May 2002 to 1 June 2003 on the incidence, aetiology, staging, diagnosis and treatment of penile cancer by a Medline search. RECENT FINDINGS:The diagnostic tools and treatment modal...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/01.mou.0000098068.73234.28

    authors: Stancik I,Höltl W

    更新日期:2003-11-01 00:00:00

  • Current status of nephron-sparing robotic partial nephrectomy.

    abstract:PURPOSE OF REVIEW:Partial nephrectomy has become the standard of treatment for renal tumors less than 4 cm in size. Recent reports have even applied this technique for T1b lesions as well. With advancement in minimally invasive techniques, laparoscopic and robotic surgeries are performed with the advantage of decreased...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e3283337b76

    authors: Hsieh TC,Jarrett TW,Pinto PA

    更新日期:2010-01-01 00:00:00

  • Lymph node dissection for renal cell carcinoma: what are we missing?

    abstract:PURPOSE OF REVIEW:The role of lymph node dissection (LND) is uncertain for patients diagnosed with renal cell carcinoma (RCC). The aim of the current review is to discuss the available literature considering the role and the impact of LND in RCC patients elected for surgical treatment. Controversies, uncertainties as w...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000312

    authors: Moschini M,Dell'Oglio P,Larcher A,Capitanio U

    更新日期:2016-09-01 00:00:00

  • Prostate cancer prevention with 5-alpha reductase inhibitors: concepts and controversies.

    abstract:PURPOSE OF REVIEW:We review the concepts surrounding prostate cancer prevention strategies with 5-alpha reductase inhibitors (5-ARIs) and the controversies associated with their use. RECENT FINDINGS:Updated data have shown no increased risk of death from the diagnosis of higher risk cancer; however, 5-ARIs remain cont...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000464

    authors: Liss MA,Thompson IM

    更新日期:2018-01-01 00:00:00

  • Orthotopic urinary diversion.

    abstract:PURPOSE OF REVIEW:Orthotopic urinary diversion has been performed for more than 30 years. Although it is considered to be the gold standard form of diversion in many centers of expertise, however it is uncommonly performed outside these institutions. The purpose of this article is to review the current indications and ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000226

    authors: Daneshmand S

    更新日期:2015-11-01 00:00:00

  • Anatomic partial nephrectomy: technique evolution.

    abstract:PURPOSE OF REVIEW:Partial nephrectomy provides equivalent long-term oncologic and superior functional outcomes as radical nephrectomy for T1a renal masses. Herein, we review the various vascular clamping techniques employed during minimally invasive partial nephrectomy, describe the evolution of our partial nephrectomy...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000140

    authors: Azhar RA,Metcalfe C,Gill IS

    更新日期:2015-03-01 00:00:00

  • Magnetic resonance imaging for urinary incontinence.

    abstract::Magnetic resonance imaging provides the most accurate, versatile and safe imaging of the pelvic floor. Images can be produced to show sections in any plane and even in three dimensions. The resolution is such that detail as good as that seen in histological sections is possible. Once standardization of data acquisitio...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200203000-00009

    authors: Stewart LH,Brush JP

    更新日期:2002-03-01 00:00:00

  • The Y chromosome and male infertility.

    abstract:PURPOSE OF REVIEW:Therapies for the treatment of severe male factor infertility have advanced well beyond our knowledge of the conditions we are treating. An intact Y chromosome is necessary for optimal spermatogenesis. It is imperative for the clinician to understand the molecular basis and clinical implications of an...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32831367dc

    authors: Sadeghi-Nejad H,Oates RD

    更新日期:2008-11-01 00:00:00

  • Urodynamic assessment of patients with stress incontinence: how effective are urethral pressure profilometry and abdominal leak point pressures at case selection and predicting outcome?

    abstract:PURPOSE OF REVIEW:Disagreement exists as to the extent of evaluation required prior to offering surgical intervention for the treatment of stress urinary incontinence in women. While few would argue that additional information can be gleaned from a properly performed urodynamic investigation, it remains unclear exactly...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200411000-00002

    authors: Lemack GE

    更新日期:2004-11-01 00:00:00

  • The prospect of gene therapy for prostate cancer: update on theory and status.

    abstract::Molecularly based novel therapeutic agents are needed to address the problem of locally recurrent, or metastatic, advanced hormone-refractory prostate cancer. Recent basic science advances in mechanisms of gene expression, vector delivery, and targeting have rendered clinically relevant gene therapy to the prostatic f...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200109000-00007

    authors: Koeneman KS,Hsieh JT

    更新日期:2001-09-01 00:00:00

  • Integrating basic science and clinical research in bladder cancer: update from the first bladder Specialized Program of Research Excellence (SPORE).

    abstract:PURPOSE OF REVIEW:To review the progress of the genitourinary SPORE (Specialized Program of Research Excellence) in bladder cancer. RECENT FINDINGS:The optimal management of bladder cancer depends on the accurate assessment of the biological potential of the disease. Methotrexate, vincristine, adriamycin and cisplatin...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200409000-00008

    authors: Highshaw RA,McConkey DJ,Dinney CP

    更新日期:2004-09-01 00:00:00

  • Common grounds for erectile dysfunction and coronary artery disease.

    abstract:PURPOSE OF REVIEW:Evidence is accumulating to consider erectile dysfunction as a vascular problem. This review focuses on background, pathophysiological mechanisms and clinical evidence of the link between erectile dysfunction and coronary artery disease. RECENT FINDINGS:The link between erectile dysfunction and coron...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200411000-00012

    authors: Montorsi P,Ravagnani PM,Galli S,Rotatori F,Briganti A,Salonia A,Dehò F,Montorsi F

    更新日期:2004-11-01 00:00:00

  • Prostate-specific membrane antigen PET/computed tomography for staging prostate cancer.

    abstract:PURPOSE OF REVIEW:Molecular imaging with PET/CT targeting the prostate-specific membrane antigen (PSMA) receptor is increasingly utilized in men with prostate cancer (PCa), with clinical indications now expanding beyond biochemical recurrence. PSMA PET/CT often detects sub-centimetre size pathologic nodes and low-volum...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000799

    authors: Ravi Kumar AS,Lawrentschuk N,Hofman MS

    更新日期:2020-09-01 00:00:00

  • Ureteroscopic lithotripsy.

    abstract::The indications for ureteroscopic lithotripsy have increased with endoscope miniaturization and powerful, precise endoscopic lithotrites like the holmium: yttrium-aluminum-garnet laser. Successful ureteropyeloscopic treatment with the currently available instrumentation and techniques is independent of the size, compo...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-199907000-00010

    authors: Grasso M 3rd

    更新日期:1999-07-01 00:00:00

  • Renal magnetic resonance angiography: an update.

    abstract::Recent developments in renal magnetic resonance angiography have led to a significant improvement in the technical success rate and diagnostic accuracy of the methods. Specifically, three-dimensional contrast-enhanced magnetic resonance angiography methods have been shown to provide a more reliable depiction of renal ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章

    doi:10.1097/00042307-199803000-00006

    authors: Grist TM

    更新日期:1998-03-01 00:00:00

  • Epidemiology of chronic prostatitis.

    abstract::Although there has been a recent surge of interest in chronic prostatitis, which hopefully will translate into advances in our understanding of the distribution and determinants of this condition, at present there is a scarcity of published epidemiologic research on chronic prostatitis. However, from the currently ava...

    journal_title:Current opinion in urology

    pub_type: 杂志文章

    doi:10.1097/00042307-199801000-00007

    authors: McNaughton Collins M,Barry MJ

    更新日期:1998-01-01 00:00:00

  • New innovative therapies for benign prostatic hyperplasia: any advance?

    abstract:PURPOSE OF REVIEW:Benign prostatic hyperplasia is the most common human neoplasm and it is the most frequent tumour requiring surgical treatment in men. Not surprisingly, interest centres on either understanding of prostatic growth during ageing or on various medical or interventional treatments. RECENT FINDINGS:Recen...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200301000-00003

    authors: Klingler HC

    更新日期:2003-01-01 00:00:00

  • Gene therapy for erectile dysfunction: where is it going?

    abstract:PURPOSE OF REVIEW:This review will summarize the most recent preclinical data from the leading US laboratories regarding the application of gene therapy to the treatment of erectile dysfunction. The implications of these findings in the field of gene therapy in general, and more specifically to the treatment of non-lif...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200211000-00010

    authors: Christ GJ

    更新日期:2002-11-01 00:00:00

  • Surgery for urogenital rhabdomyosarcoma.

    abstract::The treatment and prognosis of rhabdomyosarcoma of the urogenital tract have changed dramatically over the past few decades. Until the 1970s radical cystectomy and pelvic exenteration were the only therapeutic options in rhabdomyosarcoma of the bladder/prostate and of the vagina/uterus. Since then, multiagent chemothe...

    journal_title:Current opinion in urology

    pub_type: 社论,评审

    doi:10.1097/00042307-200111000-00001

    authors: Filipas D

    更新日期:2001-11-01 00:00:00

  • Utility of lymphadenectomy in bladder cancer: where do we stand?

    abstract:PURPOSE OF REVIEW:The aim of this review is to provide insight into the current state of lymph node dissection (LND) during radical cystectomy in patients with bladder cancer (BCa). RECENT FINDINGS:The first prospective, multicenter, randomized, phase III trial to assess the therapeutic benefit of extended versus limi...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000750

    authors: Sung HH,Lerner SP

    更新日期:2020-05-01 00:00:00