Surgery for urogenital rhabdomyosarcoma.

Abstract:

:The treatment and prognosis of rhabdomyosarcoma of the urogenital tract have changed dramatically over the past few decades. Until the 1970s radical cystectomy and pelvic exenteration were the only therapeutic options in rhabdomyosarcoma of the bladder/prostate and of the vagina/uterus. Since then, multiagent chemotherapy has achieved remarkable cure rates. Consequently, organ-saving surgical techniques were advocated, with the goal to improve patients' quality of life. The available long-term survival data with these techniques demonstrate excellent survival in rhabdomyosarcoma of the vagina/uterus, with a high percentage of organ preservation. On the contrary, increased rates of local recurrence and death from disease in patients with rhabdomyosarcoma of the bladder/prostate who undergo primary chemotherapy with or without tumour excision, and complications following combined radiotherapy critically question the long-term benefit of these organ-sparing surgical techniques in this group.

journal_name

Curr Opin Urol

authors

Filipas D

doi

10.1097/00042307-200111000-00001

subject

Has Abstract

pub_date

2001-11-01 00:00:00

pages

563-5

issue

6

eissn

0963-0643

issn

1473-6586

journal_volume

11

pub_type

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