Update on hormone-refractory prostate cancer.

Abstract:

PURPOSE OF REVIEW:Androgen deprivation therapy is the cornerstone treatment for men with de novo or recurrent metastatic prostate cancer. Unfortunately, androgen deprivation therapy is primarily palliative, with nearly all men progressing to an androgen-independent state. Hormone-refractory prostate cancer presents significant management challenges and is the focus of this review. RECENT FINDINGS:Investigations into the pathophysiology of hormone-refractory prostate cancer, the exploration of chemotherapeutic combinations, novel biological targets, skeletal protectants, and radiopharmaceuticals, as well as new prognostic tools are expanding the clinician's armamentarium and improving patient outcomes. SUMMARY:Bisphosphonates and chemotherapy are providing effective palliative approaches. Phase II trials of taxane-based regimens show higher response rates and longer survival than has typically been achieved with existing standards. Two completed randomized phase III studies to be reported in mid-2004 will more definitively answer the question of whether currently available chemotherapy can improve survival.

journal_name

Curr Opin Urol

authors

Kasamon KM,Dawson NA

doi

10.1097/00042307-200405000-00008

subject

Has Abstract

pub_date

2004-05-01 00:00:00

pages

185-93

issue

3

eissn

0963-0643

issn

1473-6586

pii

00042307-200405000-00008

journal_volume

14

pub_type

杂志文章,评审
  • Biomarkers for immunotherapy in urological cancers.

    abstract:PURPOSE OF REVIEW:Immunotherapies for urological malignancies have made tremendous progress by targeting immune checkpoints and have been implemented in clinical practice nowadays. Though siginifcant number of patients does not respond to immunotherapy. Biomarkers could help to predict response to treatment, but are st...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000465

    authors: Gust KM,Resch I,D'Andrea D

    更新日期:2018-01-01 00:00:00

  • Benign prostatic hyperplasia progression and its impact on treatment.

    abstract:PURPOSE OF REVIEW:Management of men with benign prostatic hyperplasia should reduce the lifetime risk of acute urinary retention and the need for benign prostatic hyperplasia-related surgery. A number of recent studies demonstrate that 5alpha-reductase inhibitors are unique in providing a long-term combination of impro...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200401000-00010

    authors: Djavan B,Waldert M,Ghawidel C,Marberger M

    更新日期:2004-01-01 00:00:00

  • Environmental factors promoting bladder cancer.

    abstract:PURPOSE OF REVIEW:To understand the molecular mechanisms of bladder carcinogenesis in relation to environmental carcinogens in order to provide a given population with a preventive value of bladder cancer. RECENT FINDINGS:Cigarette smoking, aromatic amines contained in dyes, chronic inflammation due to infection such ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32832eb4ef

    authors: Hirao Y,Kim WJ,Fujimoto K

    更新日期:2009-09-01 00:00:00

  • Vesicoureteral reflux and urinary tract infections.

    abstract::Urinary tract infection is a common problem in children. The combination of vesico-ureteric reflux (VUR) and urinary tract infection may predispose children to pyelonephritis and subsequent complications. This review outlines the modifications suggested in the recent literature in the protocol for investigations and d...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200011000-00009

    authors: Agarwal S

    更新日期:2000-11-01 00:00:00

  • Current trends in partial adrenalectomy.

    abstract:PURPOSE OF REVIEW:Total adrenalectomy has been the standard treatment for small adrenal masses for years. In recent times, however, partial adrenalectomy and cortex-preserving strategies are gaining more importance. Therefore, we evaluated indications, techniques and outcome of partial adrenalectomy. RECENT FINDINGS:W...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000147

    authors: Colleselli D,Janetschek G

    更新日期:2015-03-01 00:00:00

  • Development and translation of histotripsy: current status and future directions.

    abstract:PURPOSE OF REVIEW:The aim of this article is to outline the initial development of histotripsy, a noninvasive image-guided focused ultrasound technology that mechanically homogenizes targeted tissues and to describe the results of preclinical translational research directed toward urologic applications. RECENT FINDING...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000001

    authors: Roberts WW

    更新日期:2014-01-01 00:00:00

  • Penile cancer: review of the recent literature.

    abstract:PURPOSE OF REVIEW:To review recent developments in the diagnosis and treatment of penile cancer, we reviewed the medical literature from 1 May 2002 to 1 June 2003 on the incidence, aetiology, staging, diagnosis and treatment of penile cancer by a Medline search. RECENT FINDINGS:The diagnostic tools and treatment modal...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/01.mou.0000098068.73234.28

    authors: Stancik I,Höltl W

    更新日期:2003-11-01 00:00:00

  • Adolescent varicocele.

    abstract:PURPOSE OF REVIEW:Adolescent varicocele is a common lesion which remains poorly understood. Recent research in pathophysiology and surgical management has shed new light on this increasingly diagnosed clinical entity. RECENT FINDINGS:Recent research demonstrates the potential importance of heat and oxidative stress pa...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e3281ddb30c

    authors: Diamond DA

    更新日期:2007-07-01 00:00:00

  • Impact of the United States Preventive Services Task Force 'D' recommendation on prostate cancer screening and staging.

    abstract:PURPOSE OF REVIEW:In 2012, the United States Preventive Services Task Force (USPSTF) issued a grade 'D' recommendation against the use of routine prostate-specific antigen (PSA)-based screening for any men. This recommendation reflects critical misinterpretations of the available evidence base regarding benefits and ha...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000383

    authors: Eapen RS,Herlemann A,Washington SL 3rd,Cooperberg MR

    更新日期:2017-05-01 00:00:00

  • Decision making and treatment options in endourology post-coronavirus disease 2019 - adapting to the future.

    abstract:PURPOSE OF REVIEW:To describe and critically discuss the most recent evidence regarding stone management during the coronavirus disease 2019 (COVID-19) and post-COVID-19 era. RECENT FINDINGS:There is a need to plan for resuming the normal elective stone surgery in the post-COVID era, keeping a clear record of all surg...

    journal_title:Current opinion in urology

    pub_type: 杂志文章

    doi:10.1097/MOU.0000000000000857

    authors: Proietti S,Basulto-Martinez M,Pavia MP,Luciani L,Gaboardi F,Giusti G

    更新日期:2021-03-01 00:00:00

  • Transurethral resection of the prostate revisited and updated.

    abstract:PURPOSE OF REVIEW:Electrosurgical transurethral resection (TUR) of the prostate (TURP) has dominated symptomatic benign prostatic hyperplasia (s-BPH) surgical treatment for almost a century. We analysed recent TURP publications, with emphasis on durability, morbidity, new technology advantages, future generation traini...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e3283411455

    authors: Smith RD,Patel A

    更新日期:2011-01-01 00:00:00

  • New innovative therapies for benign prostatic hyperplasia: any advance?

    abstract:PURPOSE OF REVIEW:Benign prostatic hyperplasia is the most common human neoplasm and it is the most frequent tumour requiring surgical treatment in men. Not surprisingly, interest centres on either understanding of prostatic growth during ageing or on various medical or interventional treatments. RECENT FINDINGS:Recen...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200301000-00003

    authors: Klingler HC

    更新日期:2003-01-01 00:00:00

  • Synthetic slings: which material, which approach.

    abstract:PURPOSE OF REVIEW:The success in the use of the tension-free midurethral sling procedures (tension-free vaginal tape, suprapubic arch, transobturator tape) has dramatically altered the approach to the surgical management of stress urinary incontinence in women and marked a resurgence in the use of mesh. We will analyze...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/01.mou.0000232042.95427.9f

    authors: Roth CC,Holley TD,Winters JC

    更新日期:2006-07-01 00:00:00

  • Advances in laparoscopic partial nephrectomy.

    abstract:PURPOSE OF REVIEW:The advantages of the laparoscopic approach in the management of kidney tumors are unequivocal and the role of laparoscopy in nephron-sparing surgery is evolving. In a selected group of patients with small exophytic renal tumors laparoscopic partial nephrectomy became an alternative to open partial ne...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/01.mou.0000135079.98882.6d

    authors: Touijer K,Guillonneau B

    更新日期:2004-07-01 00:00:00

  • What's new in prostate cancer disease assessment in 2006?

    abstract:PURPOSE OF REVIEW:Issues relating to the disease are critical in the diagnosis, management, and prognostication of prostate cancer. RECENT FINDINGS:New data have emerged regarding the disease of prostate cancer and its precursors. The diagnosis of prostate cancer on needle biopsy has been refined because of the recent...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/01.mou.0000193389.31727.9b

    authors: Epstein JI

    更新日期:2006-05-01 00:00:00

  • Female neurogenic stress urinary incontinence.

    abstract:PURPOSE OF REVIEW:The aim of this article is to look into recent updates on the management of neurogenic stress urinary incontinence (NSUI) in adult females. RECENT FINDINGS:Recently, a small number of studies have investigated different surgical modalities in treatment of NSUI in adult females including artificial ur...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000785

    authors: Farag F,Doherty R,Arlandis S

    更新日期:2020-07-01 00:00:00

  • Vaporization vs. enucleation techniques for BPO: do we have a standard?

    abstract:PURPOSE OF REVIEW:This article discusses enucleation and vaporization procedures which have been developed on the surgical techniques of holmium laser enucleation of the prostate (HoLEP) and photoselective vaporization of the prostate (PVP) by reviewing the most recent publications. RECENT FINDINGS:Enucleation procedu...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000125

    authors: Netsch C,Bach T

    更新日期:2015-01-01 00:00:00

  • Management of urethrovaginal fistulae.

    abstract:PURPOSE OF REVIEW:Urethrovaginal fistulae are a rare condition. It is a conceptual mistake to consider urethrovaginal fistulae to be synonymous with vesicovaginal fistulae. Urethrovaginal fistulae are a different entity requiring special attention and treatment. Due to the wide variety and individuality of the clinical...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e3282feedd4

    authors: Pushkar DY,Sumerova NM,Kasyan GR

    更新日期:2008-07-01 00:00:00

  • Robotic assisted simple prostatectomy: recent advances.

    abstract:PURPOSE OF REVIEW:Robotic assisted simple prostatectomy (RASP) represents a minimally invasive evolution of traditional open simple prostatectomy for the surgical treatment of severe lower urinary tract symptoms (LUTS) because of benign prostatic enlargement (BPE). Aim of the present review is to summarize the most rec...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000499

    authors: Vince R,Hampton LJ,Vartolomei MD,Shariat SF,Porpiglia F,Autorino R

    更新日期:2018-05-01 00:00:00

  • Residual stone fragments: clinical implications and technological innovations.

    abstract:PURPOSE OF REVIEW:To summarize the recent literature on the topic of residual stone fragments in particular novel developments in this field. RECENT FINDINGS:The urological position towards residual fragments has shifted in recent years from observation, to active retrieval with innovative methods, to algorithm-based ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000571

    authors: Suarez-Ibarrola R,Hein S,Miernik A

    更新日期:2019-03-01 00:00:00

  • Hand-assisted urological laparoscopy.

    abstract::Hand-assisted laparoscopy has been successfully applied to various applications within the field of urology. Many authors have proved the safety and efficacy of this technique, as well as demonstrating improved patient recovery for such procedures as radical nephrectomy, radical nephroureterectomy and donor nephrectom...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200205000-00010

    authors: Pietrow PK,Albala DM

    更新日期:2002-05-01 00:00:00

  • Urethral pathology.

    abstract::In the present review the eligible data on urethral pathologies are critically analysed, with special attention given to unresolved controversies in this topic. The entities discussed are as follows: female circumcision as a ritualistic tradition, with many associated complications; prostatourethritis and urethral syn...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200009000-00004

    authors: El-Mekresh M

    更新日期:2000-09-01 00:00:00

  • Current and future imaging for urologic interventions.

    abstract:PURPOSE OF REVIEW:This review focuses on novel imaging techniques used for guiding urologic procedures that are likely to provide additional opportunities to physicians in the years to come. RECENT FINDINGS:In the past, most image-guided urologic procedures have utilized two-dimensional x-ray images. This review will ...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e3282f1c5d3

    authors: Nascimento RG,Coleman J,Solomon SB

    更新日期:2008-01-01 00:00:00

  • Robotic surgery for ureteropelvic junction obstruction.

    abstract:PURPOSE OF REVIEW:Robotic surgery for ureteropelvic junction obstruction is an evolving technique. We review the current literature related to this technique and discuss the current technique and outcomes of robotic pyeloplasty. RECENT FINDINGS:Recent advances in robotic-assisted surgery have allowed the successful co...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/01.mou.0000232052.74342.a0

    authors: Lee RS,Borer JG

    更新日期:2006-07-01 00:00:00

  • Lymph node dissection for renal cell carcinoma: what are we missing?

    abstract:PURPOSE OF REVIEW:The role of lymph node dissection (LND) is uncertain for patients diagnosed with renal cell carcinoma (RCC). The aim of the current review is to discuss the available literature considering the role and the impact of LND in RCC patients elected for surgical treatment. Controversies, uncertainties as w...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000312

    authors: Moschini M,Dell'Oglio P,Larcher A,Capitanio U

    更新日期:2016-09-01 00:00:00

  • Management of stones in renal transplant.

    abstract:PURPOSE OF REVIEW:Increasingly, screening of both deceased and living donor organs has led to the early detection of kidney stones prior to donation. A number of transplant recipients will still present with donor-gifted and de-novo stones. A range of treatment modalities is available in the management of renal transpl...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0b013e32835d3097

    authors: Wong KA,Olsburgh J

    更新日期:2013-03-01 00:00:00

  • Pediatric pheochromocytoma: current status of diagnostic imaging and treatment procedures.

    abstract:PURPOSE OF REVIEW:To provide an overview of relevant data available and updated recommendations for management of pediatric patients with pheochromocytoma (PCC). RECENT FINDINGS:Much of the available data surrounding pediatric PCC is in the form of case reports and case series. With the accumulation of data over time,...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000650

    authors: Peard L,Cost NG,Saltzman AF

    更新日期:2019-09-01 00:00:00

  • Current evidence for focal therapy and partial gland ablation for organ-confined prostate cancer: systematic review of literature published in the last 2 years.

    abstract:PURPOSE OF REVIEW:The shift in the diagnostic algorithm for prostate cancer to early imaging with mpMRI has resulted in many patients being diagnosed with small volume, apparently unilateral, clinically significant cancers. In these patients, a minimally invasive, nonmorbid intervention is appealing. The aim of this st...

    journal_title:Current opinion in urology

    pub_type: 杂志文章

    doi:10.1097/MOU.0000000000000838

    authors: Kayano PP,Klotz L

    更新日期:2021-01-01 00:00:00

  • New devices for kidney stone management.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to summarize recent developments in the array of devices which are commonly used by urologists in the surgical management of kidney stones. To accomplish this goal, an extensive review of recent endourology literature, conference abstracts, and publicly available document...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/MOU.0000000000000710

    authors: Terry RS,Whelan PS,Lipkin ME

    更新日期:2020-03-01 00:00:00

  • Role of phytotherapy in men with lower urinary tract symptoms.

    abstract:PURPOSE OF REVIEW:Serenoa repens extract is a popular phytotherapeutic agent in men with lower urinary tract symptoms. Although the exact mechanism of action is unknown, the agent is generally well accepted for its easy availability and good tolerability. This paper reviews the evidence of its efficacy in comparison wi...

    journal_title:Current opinion in urology

    pub_type: 杂志文章,评审

    doi:10.1097/00042307-200501000-00011

    authors: Fong YK,Milani S,Djavan B

    更新日期:2005-01-01 00:00:00