Role of phytotherapy in men with lower urinary tract symptoms.

Abstract:

PURPOSE OF REVIEW:Serenoa repens extract is a popular phytotherapeutic agent in men with lower urinary tract symptoms. Although the exact mechanism of action is unknown, the agent is generally well accepted for its easy availability and good tolerability. This paper reviews the evidence of its efficacy in comparison with placebo, 5-alpha reductase inhibitor and alpha-1 adrenoreceptor antagonist. RECENT FINDINGS:Serenoa repens extract is comparable with 5-alpha reductase (finasteride) and alpha-1 antagonist in the treatment of benign prostatic hyperplasia in terms of symptom score and peak urinary flow rate improvement, but has a lower incidence of associated sexual dysfunction. Furthermore, long-term usage (36 months) of Serenoa repens decreases the progression rate of the condition as compared with watchful waiting. In addition, the efficacies of Serenoa repens are proven in several placebo-controlled trials. SUMMARY:Serenoa repens has proven its role in the management of benign prostatic hyperplasia and will remain as a viable first-line treatment option.

journal_name

Curr Opin Urol

authors

Fong YK,Milani S,Djavan B

doi

10.1097/00042307-200501000-00011

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

45-8

issue

1

eissn

0963-0643

issn

1473-6586

pii

00042307-200501000-00011

journal_volume

15

pub_type

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