Modern pharmacotherapy for erectile dysfunction: evolving concepts with central and peripheral acting agents.

Abstract:

:Pharmacotherapy for men experiencing erectile dysfunction has undergone dramatic advances over the past 5 years with the introduction of an effective oral agent. Sildenafil has increased the pool of couples seeking treatment for this important health issue as well as expanding the numbers of physicians treating it. Research into the growing field of erectile dysfunction is expanding at a rapid pace. Independent investigators worldwide now regularly contribute to our body of scientific knowledge. Novel oral therapies targeted at specific points along the erectile cascade are undergoing pre-clinical and early phase registration trials with the promise of rapid action, extended duration of responsiveness and an improved side effect profile. In this review, we have highlighted recent information on the next generation of phosphodiesterase inhibitors and summarized the evolving research into centrally acting agents, which may lead to effective combination therapy.

journal_name

Curr Opin Urol

authors

Brock GB,Bochinski D

doi

10.1097/00042307-200111000-00011

subject

Has Abstract

pub_date

2001-11-01 00:00:00

pages

625-30

issue

6

eissn

0963-0643

issn

1473-6586

journal_volume

11

pub_type

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