New innovative therapies for benign prostatic hyperplasia: any advance?

abstract：:Molecularly based novel therapeutic agents are needed to address the problem of locally recurrent, or metastatic, advanced hormone-refractory prostate cancer. Recent basic science advances in mechanisms of gene expression, vector delivery, and targeting have rendered clinically relevant gene therapy to the prostatic f...

journal_title：Current opinion in urology

authors： Koeneman KS,Hsieh JT

更新日期：2001-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Radical cystectomy and urinary diversion is the accepted standard of care for invasive bladder cancer. Although orthotopic neobladder is the preferred method of urinary diversion in men, less experience is available for women. Recent studies and reports on this subject are summarized and reviewed. RE...

journal_title：Current opinion in urology

authors： Kübler H,Gschwend JE

更新日期：2011-11-01 00:00:00

abstract：PURPOSE OF REVIEW:High-risk prostate cancer often represents a lethal disease requiring timely diagnosis and effective therapy. Standardized criteria that define high-risk prostate cancer have yet to be established, rendering the discrimination of high-risk from nonhigh-risk patients a challenge. This review summarizes...

journal_title：Current opinion in urology

authors： Goldberg H,Baniel J,Yossepowitch O

更新日期：2013-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Issues relating to the disease are critical in the diagnosis, management, and prognostication of prostate cancer. RECENT FINDINGS:New data have emerged regarding the disease of prostate cancer and its precursors. The diagnosis of prostate cancer on needle biopsy has been refined because of the recent...

journal_title：Current opinion in urology

authors： Epstein JI

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The aim of this article is to outline the initial development of histotripsy, a noninvasive image-guided focused ultrasound technology that mechanically homogenizes targeted tissues and to describe the results of preclinical translational research directed toward urologic applications. RECENT FINDING...

journal_title：Current opinion in urology

authors： Roberts WW

更新日期：2014-01-01 00:00:00

abstract：:This paper reviews the major publications over the past year regarding upper urinary tract reconstruction. Controversies in the diagnosis of ureteropelvic junction obstruction and in the surgical repair of the obstructed upper urinary tract are discussed. Special emphasis is placed on issues surrounding minimally inva...

journal_title：Current opinion in urology

authors： Jayanthi VR

更新日期：1998-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Extracorporeal shock wave lithotripsy (ESWL) is the preferred modality for the treatment of renal and upper ureteric calculi. The present review focuses on the limitations of ESWL, where recent developments have tried to identify patients who are unlikely to succeed with ESWL and where improvements in...

journal_title：Current opinion in urology

authors： Madaan S,Joyce AD

更新日期：2007-03-01 00:00:00

abstract：PURPOSE OF REVIEW:We examine the role of 5-alpha reductase inhibitors in prevention and diagnosis of prostate cancer, highlight the basic science supporting this role, and analyze the phase III clinical trials addressing the association between 5-alpha reductase inhibitor use and prostate cancer. RECENT FINDINGS:To da...

journal_title：Current opinion in urology

authors： Reed AB,Parekh DJ

更新日期：2009-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Radical prostatectomy is the standard treatment for localized prostate cancer; its translation to a laparoscopic approach is considered today not only as feasible and reproducible but also as a valid and teachable alternative to its open counterpart. Beyond the "classical" transperitoneal antegrade ro...

journal_title：Current opinion in urology

authors： van Velthoven RF

更新日期：2005-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite standard treatment with transurethral resection (TUR) and adjuvant Bacillus Calmette-Guérin (BCG), a large percentage of high-risk bladder cancer (HRBC) recur, and some progress. On the basis of review of the current guidelines and literature, we have developed actualized clinical and molecula...

journal_title：Current opinion in urology

authors： Rodríguez Faba O,Palou J

更新日期：2012-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Postbiopsy infections (PBIs) are among the most common complications associated with transrectal ultrasound-guided prostate biopsy (TRUSPB). This article discusses the pathogenesis of TRUSPB-associated infectious complications and reviews the most recent findings on techniques to prevent PBIs. RECENT...

journal_title：Current opinion in urology

authors： Fontana M,Boeri L,Montanari E

更新日期：2018-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Secondary data analysis has become increasingly common in health services research, specifically comparative effectiveness research. While a comprehensive study of the techniques and methods for secondary data analysis is a wide-ranging topic, we sought to perform a descriptive study of some key metho...

journal_title：Current opinion in urology

authors： Cole AP,Trinh QD

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Systemic treatment options for metastatic hormone-sensitive prostate cancer (mHSPC) have recently shifted from the traditional androgen deprivation therapy (ADT) monotherapy to multidrug approaches incorporating drugs initially approved for castration-resistant state and ADT. However, clinicians have ...

journal_title：Current opinion in urology

authors： Baston C,Preda A,Guler-Margaritis SS,Sinescu I,Gingu C

更新日期：2020-07-01 00:00:00

abstract：:This review discusses the contemporary management of urethral trauma and post-traumatic urethral strictures occurring in both the anterior and posterior urethra. Experience in the full spectrum of urethral reconstructive procedures is important. The initial management of patients relies upon adequate drainage of the b...

journal_title：Current opinion in urology

authors： Chapple CR,Png D

更新日期：1999-05-01 00:00:00

abstract：PURPOSE OF REVIEW:To perform a bicenter, retrospective study of perioperative outcomes of retroperitoneal versus transperitoneal robotic-assisted laparoscopic partial nephrectomy (RALPN) and assess costs using time-driven activity-based costing (TDABC). We identified 355 consecutive patients who underwent RALPN at Univ...

journal_title：Current opinion in urology

authors： Laviana AA,Tan HJ,Hu JC,Weizer AZ,Chang SS,Barocas DA

更新日期：2018-03-01 00:00:00

abstract：:In the present review the eligible data on urethral pathologies are critically analysed, with special attention given to unresolved controversies in this topic. The entities discussed are as follows: female circumcision as a ritualistic tradition, with many associated complications; prostatourethritis and urethral syn...

journal_title：Current opinion in urology

authors： El-Mekresh M

更新日期：2000-09-01 00:00:00

abstract：PURPOSE OF REVIEW:This review focuses on recent advances in molecular embryology of the upper and lower urinary tract with an emphasis on clinical correlation in order to gain a better understanding for the mechanism of congenital anomalies. RECENT FINDINGS:Normal morphogenesis of the kidney, ureteral bud differentiat...

journal_title：Current opinion in urology

authors： Shapiro E

更新日期：2009-07-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review was to report on the latest world literature relating to paediatric stone disease. Inevitably, because of the small numbers, the literature is limited and consists mainly of case series from individual centres. There is also a wide variation in criteria and techniques, makin...

journal_title：Current opinion in urology

authors： Thomas BG

更新日期：2010-03-01 00:00:00

abstract：:Urinary tract infection is a common problem in children. The combination of vesico-ureteric reflux (VUR) and urinary tract infection may predispose children to pyelonephritis and subsequent complications. This review outlines the modifications suggested in the recent literature in the protocol for investigations and d...

journal_title：Current opinion in urology

authors： Agarwal S

更新日期：2000-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Adolescent varicocele is a common lesion which remains poorly understood. Recent research in pathophysiology and surgical management has shed new light on this increasingly diagnosed clinical entity. RECENT FINDINGS:Recent research demonstrates the potential importance of heat and oxidative stress pa...

journal_title：Current opinion in urology

authors： Diamond DA

更新日期：2007-07-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the latest status on prognostic factors in renal cell carcinoma (RCC). RECENT FINDINGS:Many predictive and prognostic factors can help differentiate between favorable and unfavorable RCC phenotypes. There currently exist several clinical and/or pathological, and biological factors, which ha...

journal_title：Current opinion in urology

authors： Sun M,Shariat SF,Karakiewicz PI

更新日期：2010-09-01 00:00:00

abstract：:Recent years have seen notable advances in virtual reality technology and increased interest in potential medical applications. Computed tomography and magnetic resonance imaging data sets, historically viewed as axial images, may now be used to construct a virtual reality endoscopic image, and navigator software syst...

journal_title：Current opinion in urology

authors： Allan JD,Tolley DA

更新日期：2001-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Overdiagnosis has become a major problem in medicine in general and cancer in particular. This is a summary of this problem. RECENT FINDINGS:Because of earlier detection, the nature of cancer has changed, from a disease usually diagnosed at a late and incurable stage to a heterogeneous condition that...

journal_title：Current opinion in urology

authors： Klotz L

更新日期：2012-05-01 00:00:00

abstract：:Techniques that are aimed at regeneration of human tissues and organs (tissue engineering) have recently entered into clinical practice. Tissue engineering is currently among the fastest growing areas in medicine, and involves the application of the principles of biology and engineering to the development of functiona...

journal_title：Current opinion in urology

authors： Gustafson CJ,Kratz G

更新日期：2001-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Tissue engineering is a rapidly advancing technology that is shifting from the laboratory to urological practice. The review explores recent developments and considers the relationship to existing treatments. RECENT FINDINGS:Different strategies to generate transplantable tissue grafts in vitro and h...

journal_title：Current opinion in urology

authors： Wood D,Southgate J

更新日期：2008-11-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the progress of the genitourinary SPORE (Specialized Program of Research Excellence) in bladder cancer. RECENT FINDINGS:The optimal management of bladder cancer depends on the accurate assessment of the biological potential of the disease. Methotrexate, vincristine, adriamycin and cisplatin...

journal_title：Current opinion in urology

authors： Highshaw RA,McConkey DJ,Dinney CP

更新日期：2004-09-01 00:00:00

abstract：PURPOSE OF REVIEW:Testicular microlithiasis becomes a greater interdisciplinary issue among urologists, andrologists, gynecologists dedicated to reproductive medicine, pediatricians, radiologists and pathologists. Proposed management ranges from benign neglect, instructing self-examination over follow-up once, regular ...

journal_title：Current opinion in urology

authors： Meissner A,Mamoulakis C,de la Rosette JJ,Pes MP

更新日期：2009-11-01 00:00:00

abstract：PURPOSE OF REVIEW:Molecular imaging with PET/CT targeting the prostate-specific membrane antigen (PSMA) receptor is increasingly utilized in men with prostate cancer (PCa), with clinical indications now expanding beyond biochemical recurrence. PSMA PET/CT often detects sub-centimetre size pathologic nodes and low-volum...

journal_title：Current opinion in urology

authors： Ravi Kumar AS,Lawrentschuk N,Hofman MS

更新日期：2020-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The pace of technology development with single-use endoscopy has led to a range of disposable ureteroscopes. We review the development of single-use scopes, deconstruct the basic design and functional characteristics of available devices, and discuss future directions for next-generation platforms. R...

journal_title：Current opinion in urology

authors： Bahaee J,Plott J,Ghani KR

更新日期：2021-03-01 00:00:00

abstract：PURPOSE OF REVIEW:Cytoreductive nephrectomy has an established role in management of metastatic renal cell carcinoma when performed in properly selected patients prior to administration of systemic cytokine therapy. Within the past several years, novel molecular targeted agents have not only revolutionized management o...

journal_title：Current opinion in urology

authors： Margulis V,Matin SF,Wood CG

更新日期：2008-09-01 00:00:00