Cathepsin K modulates invasion, migration and adhesion of oral squamous cell carcinomas in vitro.

abstract：OBJECTIVES:To find out if strontium is incorporated into plaque and enamel in vivo during a 2-week rinsing period with a chlorhexidine-fluoride-strontium solution and to determine the effects of the rinsing on the numbers of mutans streptococci and lactobacilli in plaque. SUBJECTS AND METHODS:A total of 18 adult parti...

journal_title：Oral diseases

authors： Spets-Happonen S,Seppä L,Korhonen A,Alakuijala P

更新日期：1998-06-01 00:00:00

abstract：OBJECTIVE:To investigate the specific matrix metalloproteinases (MMPs) targeting desmoglein 3 (Dsg3) in apoptotic keratinocytes. METHOD:Inhibitor studies on cultured keratinocytes and Western blot analysis. RESULTS:Blocking of MMP-9 activity strongly reduces shedding of Dsg3 from cell surface. MMP-2 has a less releva...

journal_title：Oral diseases

authors： Cirillo N,Femiano F,Gombos F,Lanza A

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:To explore the potential of detecting the level of proinflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha), interleukin-1-alpha (IL-1-alpha), IL-6, and IL-8 in whole unstimulated saliva (WUS) in monitoring the therapeutic effects of topical dexamethasone on these salivary cytokines in subjects with...

journal_title：Oral diseases

authors： Rhodus NL,Cheng B,Bowles W,Myers S,Miller L,Ondrey F

更新日期：2006-03-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC) is one of the most morbid, mortal, and genetically diverse malignancies. Although HNSCC is heterogeneous in nature, alterations in major components of the PI3K/Akt/mTOR pathway are consistently observed throughout the majority of HNSCC cases. These alterations include gene...

journal_title：Oral diseases

authors： Vander Broek R,Mohan S,Eytan DF,Chen Z,Van Waes C

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:Bisphosphonates are widely used to treat bone diseases such as osteoporosis. However, they may cause osteonecrosis of the jaw. Here, we investigated whether in vivo exposure to bisphosphonates has a different effect on long bone and jaw osteoclasts, and on the turnover of these different bones. MATERIALS AN...

journal_title：Oral diseases

authors： Vermeer J,Renders G,van Duin MA,Jansen I,Bakker LF,Kroon SA,de Vries TJ,Everts V

更新日期：2017-01-01 00:00:00

abstract：:Cannabis, also known as marijuana, is one of the most commonly used substances for medical and recreational purposes globally. With the trend of global legalization of medical use of cannabis and even the recreational use, the prevalence of recreational use of cannabis has increased markedly over the past few years. C...

journal_title：Oral diseases

authors： Liu C,Qi X,Yang D,Neely A,Zhou Z

更新日期：2020-10-01 00:00:00

abstract：:Orofacial granulomatosis (OFG) is the presence of persistent enlargement of the soft tissues of the oral and maxillofacial region, characterized by non-caseating granulomatous inflammation in the absence of diagnosable systemic Crohn's disease (CD) or sarcoidosis. Over 20 years have passed since OFG was first describe...

journal_title：Oral diseases

authors： Grave B,McCullough M,Wiesenfeld D

更新日期：2009-01-01 00:00:00

abstract：:HIV infection and AIDS are spreading rapidly among the world's children, especially among African-American and Hispanic children in the USA, and those in developing countries. Although recent research has identified several ways of preventing perinatal transmission of HIV, most of these methods are too expensive for w...

journal_title：Oral diseases

authors： Ramos-Gomez F

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to investigate the association of the shape of the mandibular cortex on panoramic radiographs with the risk of an osteoporosis diagnosis without prevalent fractures and with the risk of osteoporotic fractures in Japanese men and women. SUBJECTS AND METHODS:One thousand and twen...

journal_title：Oral diseases

authors： Yamada S,Uchida K,Iwamoto Y,Sugino N,Yoshinari N,Kagami H,Taguchi A

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVE:To examine whether transient receptor potential vanilloid 2 (TRPV2) contributes to the changes in intra-oral thermal and mechanical sensitivity following the incision of buccal mucosa. MATERIALS AND METHODS:Buccal mucosal pain threshold was measured after the incision. Changes in the number of TRPV2-immunore...

journal_title：Oral diseases

authors： Urata K,Shinoda M,Ikutame D,Iinuma T,Iwata K

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:We investigated whether 25-hydroxyvitamin D concentration is independently associated with dental caries among adults in the United States. SUBJECTS AND METHODS:This investigation was a cross-sectional study. A total of 4,244 participants (aged 20-80 years) were enrolled through the 2007-2008 National Healt...

journal_title：Oral diseases

authors： Zhou F,Zhou Y,Shi J

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The purposes of this study were to assess the influence of age on oral squamous cell carcinoma patients and sought to analyze the reasons that may contribute to this difference. METHODS:This study enrolled 2,782 patients included 2,443 patients in a retrospective cohort to find the influence of age and 339 ...

journal_title：Oral diseases

authors： Xu Q,Wang C,Li B,Kim K,Li J,Mao M,Qin L,Li H,Huang X,Xing R,Han Z,Feng Z

更新日期：2019-04-01 00:00:00

abstract：:Currently, 4 novel Direct Oral Anticoagulants (DOACs) were approved by the FDA. This review focuses on these agents and proposes a matrix for the general dentists to assess bleeding risk in dental management of patient on DOACs. The outline covers the pharmacology of DOACs (rivaroxaban, apixaban, edoxaban and dabigatr...

journal_title：Oral diseases

authors： Elad S,Marshall J,Meyerowitz C,Connolly G

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Mandibular osteoradionecrosis (ORN) is a devastating complication secondary to the radiotherapy of head and neck cancer. The nutritional status of ORN patients is compromised, but remains rarely studied. We aimed to evaluate the overall nutritional status of patients with ORN and explore the risk factors beh...

journal_title：Oral diseases

authors： Huang Q,He X,Yang WF,Ye J,Lin Z,Xiong C,Liang YJ

更新日期：2020-12-28 00:00:00

abstract：OBJECTIVE:To study the incidence and magnitude of bacteremia after dental extraction and supragingival scaling. SUBJECTS AND METHODS:Blood samples were taken before and 5 and 30 min after dental extraction and supragingival scaling from individuals at high (n = 44) or negligible risk (n = 51) for infective endocarditi...

journal_title：Oral diseases

authors： Reis LC,Rôças IN,Siqueira JF Jr,de Uzeda M,Lacerda VS,Domingues R,Miranda KR,Saraiva RM

更新日期：2018-05-01 00:00:00

abstract：:Hyaline ring granuloma (HRG) is a rare and atypical foreign-body granulomatous chronic inflammatory condition. Our aim was to make a critical review of the literature cases and also to illustrate histochemical and immunohistochemical findings of a new case. A modified PICO strategy was used. Inclusion criteria were me...

journal_title：Oral diseases

authors： Kimura TC,Carneiro MC,Coelho YFS,de Sousa SCOM,Veltrini VC

更新日期：2020-01-24 00:00:00

abstract：:The aim of this article is to review the clinical, pathophysiological, and therapeutic aspects of traumatically induced trigeminal nerve pain. We introduce a new and, in our view, more accurate terminology: peripheral painful traumatic trigeminal neuropathy (PPTTN) to define this patient group. The proposed pathophysi...

journal_title：Oral diseases

authors： Benoliel R,Kahn J,Eliav E

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To review a series of patients with sore, burning mouth treated with alpha-lipoic acid between 2000 and May 2006 and subjectively evaluate improvement in symptoms. DESIGN:Retrospective review of medical records of 195 consecutive patients who sought treatment for sore, burning mouth. Treatment of 47 patients...

journal_title：Oral diseases

authors： Steele JC,Bruce AJ,Drage LA,Rogers RS 3rd

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:The traditional, biochemical and enzymatic methods of identifying Actinomyces species are frequently confounded by the similar phenotypic characteristics shared by the different members of this genus. Therefore, we developed novel species-specific oligonucleotide probes to accurately speciate seven pathogenic...

journal_title：Oral diseases

authors： Tang G,Yip HK,Luo G,Cheung BP,Shen S,Samaranayake LP

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVES AND DESIGN:A preceding paper has noted a detection of defensin-1 (HNP-1), a peptide with antimicrobial and cytotoxic properties, in the saliva of patients with oral squamous cell carcinoma. The present study deals with the presence of HNP-1 in the saliva of patients with various oral diseases. METHODS:Whole...

journal_title：Oral diseases

authors： Mizukawa N,Sugiyama K,Ueno T,Mishima K,Takagi S,Sugahara T

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:Transforming growth factor-beta (TGF-β) proteins are involved in epithelial keratinization. The major function of latent TGF-β binding proteins (LTBPs) is modulating TGF-β activity. However, whether LTBP-1 and LTBP-2 play roles in gingiva keratinization remains unclear. MATERIALS AND METHODS:Human keratinize...

journal_title：Oral diseases

authors： Chiang MS,Yang JR,Liao SC,Hsu CC,Hsu CW,Yuan K

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:To test whether the submandibular/sublingual (SMSL) salivary secretion, mucin concentration and candida carriage status were altered in human immunodeficiency virus-positive (HIV+) patients. SUBJECTS AND METHODS:SMSL saliva collected from 48 HIV-infected and 31 HIV-negative men were analyzed for flow rates,...

journal_title：Oral diseases

authors： Jainkittivong A,Lin AL,Johnson DA,Langlais RP,Yeh CK

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to examine the relationship between active osteoclasts, as defined by positive nuclear NFATc1 signals, and the clinical behaviors of oral giant cell granulomas. MATERIALS AND METHODS:NFATc1 immunohistochemical and TRAP-Cbfa1 double immunofluorescence stainings were performed on 9 ca...

journal_title：Oral diseases

authors： Yoon JH,Li M,Basile JR,Lin YL

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate the prevalence of sleep bruxism in children in Japan, and its relationships with sleep-related factors and daytime problematic behavior. SUBJECTS AND METHODS:Guardians of 6023 children aged 2-12 years completed the Japanese Sleep Questionnaire. Multiple regression ...

journal_title：Oral diseases

authors： Tachibana M,Kato T,Kato-Nishimura K,Matsuzawa S,Mohri I,Taniike M

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:To develop a novel test for chronic ulcerative stomatitis (CUS), a chronic immunologically mediated condition that produces oral ulcerations. Current diagnostic methods require expensive and technically demanding in situ immunofluorescence (IF) studies. DESIGN:An Enzyme-Linked ImmunoSorbent Assay (ELISA) was...

journal_title：Oral diseases

authors： Solomon LW,Stark PC,Winter L,Kumar V,Sinha S

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:The incidence of gingival overgrowth among renal transplant patients treated with cyclosporine A ranges from 13% to 84.6%, and the overgrowth is not only esthetic but also a medical problem. We studied the determination of association between TGF-β1 (TGFB1) gene polymorphism and gingival overgrowth in kidney...

journal_title：Oral diseases

authors： Kozak M,Kurzawski M,Wajda A,Lapczuk J,Lipski M,Dziewanowski K,Drozdzik M

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVES:To propose the application of the concept of geriatric syndrome for common geriatric oral and maxillofacial dysfunctions and to suggest the necessity of developing effective evaluation methods for oral and maxillofacial frailty. DESIGN:The concepts of frailty and geriatric syndrome based on multi-morbidity ...

journal_title：Oral diseases

authors： Nam Y,Kim NH,Kho HS

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:We aimed to investigate BRAF V600E percentage immunohistochemically in ameloblastomas of a single institute cohort. We were interested if age, location, histological properties, or tumor recurrence depend on the BRAF status. SUBJECTS, MATERIALS AND METHODS:We had 36 formalin-fixed, paraffin-embedded amelobl...

journal_title：Oral diseases

authors： Kelppe J,Thorén H,Ristimäki A,Haglund C,Sorsa T,Hagström J

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine any association between anxiety and salivary cortisol levels in oral lichen planus (OLP) patients by the case-control method. DESIGN RELEVANT: Forty patients with OLP were evaluated. The OLP diagnosis was established through a composite of accepted clinical and histopath...

journal_title：Oral diseases

authors： Koray M,Dülger O,Ak G,Horasanli S,Uçok A,Tanyeri H,Badur S

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:To analyze and compare periodontal parameters in chronic renal failure (CRF) patients undergoing peritoneal dialysis (PD) therapy with a group of patients on hemodialysis (HD) treatment and healthy controls (C). PARTICIPANTS:Seventy-five PD patients (mean age: 44 +/- 12 years) were matched with 41 HD patient...

journal_title：Oral diseases

authors： Bayraktar G,Kurtulus I,Kazancioglu R,Bayramgurler I,Cintan S,Bural C,Bozfakioglu S,Besler M,Trablus S,Issever H,Yildiz A

更新日期：2008-03-01 00:00:00