Orofacial granulomatosis--a 20-year review.

Abstract:

:Orofacial granulomatosis (OFG) is the presence of persistent enlargement of the soft tissues of the oral and maxillofacial region, characterized by non-caseating granulomatous inflammation in the absence of diagnosable systemic Crohn's disease (CD) or sarcoidosis. Over 20 years have passed since OFG was first described and an extensive review of the literature reveals that there is no consensus whether OFG is a distinct clinical disorder or an initial presentation of CD or sarcoidosis. Furthermore, the precise cause of OFG is still unknown although several theories have been suggested including infection, genetic predisposition and allergy. The clinical outcome of OFG patients continues to be unpredictable. Current therapies remain unsatisfactory. Regular clinical review is indicated to identify the development of gastrointestinal or systemic involvement. The aim of this review was to analyse the developments in our understanding of the aetiology, pathogenesis and treatment protocols, with particular emphasis on management and outcomes of OFG since this entity was first described in 1985.

journal_name

Oral Dis

journal_title

Oral diseases

authors

Grave B,McCullough M,Wiesenfeld D

doi

10.1111/j.1601-0825.2008.01500.x

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

46-51

issue

1

eissn

1354-523X

issn

1601-0825

pii

ODI1500

journal_volume

15

pub_type

杂志文章,评审
  • Oral bacterial diversity is inversely correlated with mucosal inflammation.

    abstract:OBJECTIVE:We investigated the relationship amongst the oral mucosal bacterial community, clinical severity and inflammatory markers in the two most common immune-mediated oral mucosal diseases, namely recurrent aphthous stomatitis (RAS) and oral lichen planus (LP). METHODS:Patients with RAS (n = 15) and LP (n = 18) an...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13420

    authors: Hijazi K,Morrison RW,Mukhopadhya I,Martin B,Gemmell M,Shaw S,Santoro F

    更新日期:2020-10-01 00:00:00

  • Traditional Chinese medicine and oral diseases: today and tomorrow.

    abstract::With a history of over 2000 years, traditional Chinese medicine (TCM) evolves into a unique system of diagnosing and treating illnesses. It is a challenge to convey the fundamentals of this traditional medicine to our Western colleagues because of the differences in language, philosophy and concept of diagnosis and tr...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/j.1601-0825.2010.01706.x

    authors: Zheng LW,Hua H,Cheung LK

    更新日期:2011-01-01 00:00:00

  • Oral epithelial cells and their interactions with HIV-1.

    abstract::As the AIDS pandemic has continued, our understanding of the events that occur during the entry and infection of conventional, susceptible cells has increased dramatically, leading to the development of control therapies for HIV-infected individuals. However, an ongoing hole in our understanding is how HIV crosses the...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.12410

    authors: Moyes DL,Islam A,Kohli A,Naglik JR

    更新日期:2016-04-01 00:00:00

  • Serum microRNAs as potential biomarkers of mandibular prognathism.

    abstract:OBJECTIVES:The aim of the study was to determine whether the expression levels of specific circulating serum microRNAs (miRNAs) are associated with mandibular prognathism (MP). METHODS:Sixty subjects in the early permanent dentition stage and 23 in the mixed dentition stage with MP were identified. Sixty-eight normal ...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12073

    authors: Gu Y,Zhang Y,Zhao C,Pan Y,Smales RJ,Wang H,Ni Y,Zhang H,Ni J,Ma J,Wang L

    更新日期:2014-01-01 00:00:00

  • Tooth ultrastructure of a novel COL1A2 mutation expanding its genotypic and phenotypic spectra.

    abstract:OBJECTIVES:To investigate tooth ultrastructure and mutation of two patients in a family affected with osteogenesis imperfecta (OI) type IV and dentinogenesis imperfecta (DGI). METHODS:Mutations were detected by whole exome and Sanger sequencing. The permanent second molar obtained from the proband (DGI1) and the prima...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13657

    authors: Intarak N,Budsamongkol T,Theerapanon T,Chanamuangkon T,Srijunbarl A,Boonprakong L,Porntaveetus T,Shotelersuk V

    更新日期:2020-09-29 00:00:00

  • The microbiome-systemic diseases connection.

    abstract::The human microbiome consists of all microorganisms occupying the skin, mucous membranes and intestinal tract of the human body. The contact of the mucosal immune system with the human microbiome is a balanced interplay between defence mechanisms of the immune system and symbiotic or pathogenic microbial factors, such...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.12472

    authors: van der Meulen TA,Harmsen H,Bootsma H,Spijkervet F,Kroese F,Vissink A

    更新日期:2016-11-01 00:00:00

  • Practices of Maryland dentists: oral cancer prevention and early detection--baseline data from 1995.

    abstract:OBJECTIVES:To investigate practices and opinions of general dentists in Maryland, USA, related to oral and pharyngeal cancer prevention and early detection. DESIGN AND METHODS:A pre-tested, 34-item questionnaire, cover letter and addressed, stamped envelope were mailed in the summer, 1995, to a simple random sample of...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2000.tb00140.x

    authors: Horowitz AM,Drury TF,Canto MT

    更新日期:2000-09-01 00:00:00

  • Decreased submandibular adiponectin is involved in the progression of autoimmune sialoadenitis in non-obese diabetic mice.

    abstract:OBJECTIVE:To investigate a possible role of adiponectin in the pathogenesis of autoimmune sialoadenitis in non-obese diabetic (NOD) mouse model of Sjögren's syndrome. MATERIALS AND METHODS:Expression of adiponectin and its receptors (AdipoR1/2) was detected by PCR, immunoblotting, or immunofluorescence. The level of a...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12197

    authors: Su YC,Xiang RL,Zhang Y,Ding C,Cong X,Guo XH,Yang NY,Hua H,Wu LL,Yu GY

    更新日期:2014-11-01 00:00:00

  • Stimulatory response of neutrophils from periodontitis patients with periodontal pathogens.

    abstract:OBJECTIVE:Neutrophils play a crucial role in the defense of invading bacteria by releasing biologically active molecules. The response of peripheral blood neutrophils was studied in periodontitis-affected patients and in healthy controls towards stimulation to Porphyromonas gingivalis (Pg) and Actinobacillus actinomyce...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2006.01323.x

    authors: Restaíno CG,Chaparro A,Valenzuela MA,Kettlun AM,Vernal R,Silva A,Puente J,Jaque MP,León R,Gamonal J

    更新日期:2007-09-01 00:00:00

  • Functional variants of IL4 and IL6 genes and risk of tobacco-related oral carcinoma in high-risk Asian Indians.

    abstract:BACKGROUND:Tobacco-related oral squamous cell carcinoma (OSCC) is one of the most common cancers involving Indian males. We assessed the association of IL4 promoter -589 T>C, -33 T>C, and IL6-174 G>C functional genetic polymorphisms with tobacco-related OSCC in Asian Indians. PATIENTS AND METHODS:The IL4 and IL6 promo...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2011.01831.x

    authors: Gaur P,Mittal M,Mohanti B,Das S

    更新日期:2011-10-01 00:00:00

  • The homeobox HOXB13 is expressed in human minor salivary gland.

    abstract:BACKGROUND:Homeobox are a family of developmental genes involved in morphogenesis and cellular differentiation. Participation of homeobox within normal and malignant tissue has been recently discussed in the literature. OBJECTIVE:To analyze the presence of HOXB13 transcript expression in human minor salivary gland. M...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2005.01218.x

    authors: Cazal C,Sobral AP,de Almeida FC,das Graças Silva-Valenzuela M,Durazzo MD,Nunes FD

    更新日期:2006-07-01 00:00:00

  • The effect of smoking on gingival crevicular fluid peptidoglycan recognition protein-1 level following initial periodontal therapy in chronic periodontitis.

    abstract:OBJECTIVE:To determine the effect of smoking on peptidoglycan recognition protein (PGRP)-1 levels in gingival crevicular fluid (GCF) in smokers and non-smokers with chronic periodontitis (CP) following initial periodontal therapy. SUBJECTS AND METHODS:A total of 40 patients with CP (20 smokers (S + CP) and 20 non-smok...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13207

    authors: Karsiyaka Hendek M,Kisa U,Olgun E

    更新日期:2020-01-01 00:00:00

  • Effect of HAART on salivary gland function in the Women's Interagency HIV Study (WIHS).

    abstract:OBJECTIVE:To determine the impact of highly active antiretroviral therapy (HAART) on salivary gland function in human immunodeficiency virus (HIV) positive women from the Women's Interagency HIV Study (WIHS). DESIGN:Longitudinal cohort study. SUBJECTS AND METHODS:A total of 668 HIV positive women from the WIHS cohort...

    journal_title:Oral diseases

    pub_type: 杂志文章,多中心研究

    doi:10.1111/j.1601-0825.2008.01456.x

    authors: Navazesh M,Mulligan R,Karim R,Mack WJ,Ram S,Seirawan H,Greenspan J,Greenspan D,Phelan J,Alves M,Oral Substudy of the Women's Interagency HIV Study Collaborative Study Group*.

    更新日期:2009-01-01 00:00:00

  • Micronuclear and sister chromatid exchange analyses in peripheral lymphocytes of patients with oral lichen planus--a pilot study.

    abstract:OBJECTIVE:The purpose of this study was to determine the genetic instability of peripheral blood lymphocytes from patients diagnosed with oral lichen planus (OLP) by investigation of frequencies of micronuclei (MN) and sister chromatid exchange (SCE). MATERIALS AND METHODS:A total of 22 newly diagnosed and untreated p...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2009.01576.x

    authors: Ergun S,Warnakulasuriya S,Duman N,Saruhanoğlu A,Sevinç B,Oztürk S,Ozel S,Cefle K,Palanduz S,Tanyeri H

    更新日期:2009-10-01 00:00:00

  • Oral potentially malignant disorders: A consensus report from an international seminar on nomenclature and classification, convened by the WHO Collaborating Centre for Oral Cancer.

    abstract::Oral potentially malignant disorders (OPMDs) are associated with an increased risk of occurrence of cancers of the lip or oral cavity. This paper presents an updated report on the nomenclature and the classification of OPMDs, based predominantly on their clinical features, following discussions by an expert group at a...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.13704

    authors: Warnakulasuriya S,Kujan O,Aguirre-Urizar JM,Bagan JV,González-Moles MÁ,Kerr AR,Lodi G,Mello FW,Monteiro L,Ogden GR,Sloan P,Johnson NW

    更新日期:2020-10-31 00:00:00

  • siRNA-mediated gene silencing in the salivary gland using in vivo microbubble-enhanced sonoporation.

    abstract:OBJECTIVES:siRNA-induced gene silencing in the salivary gland using microbubble-enhanced sonoporation was used to develop an in vivo gene knockdown technique. METHODS:siRNA targeting rat glyceraldehyde-3-phosphate dehydrogenas (GAPDH) was mixed with echo-enhanced microbubbles and reverse-injected into rat parotid glan...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2009.01579.x

    authors: Sakai T,Kawaguchi M,Kosuge Y

    更新日期:2009-10-01 00:00:00

  • Social and behavioural determinants of areca nut consumption in adolescents.

    abstract:OBJECTIVE:This study aimed to investigate the prevalence of areca nut consumption and to identify social and behavioural determinants among a Taiwanese adolescent population. SUBJECTS AND METHODS:A random sample of 5,343 high school students aged between 15-18 years in Kaohsiung, Taiwan, participated in the study. Par...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.13467

    authors: Huang B,Zachar JJ

    更新日期:2020-11-01 00:00:00

  • Current and historical involvement of dentistry in child protection and a glimpse of the future.

    abstract::Dental teams have been involved with child protection for over 40 years. This brief review summarises their involvement in the detection of various types of child abuse and goes on to discuss the gap between the proportions of dental professionals who suspect child abuse or neglect in their paediatric patients and tho...

    journal_title:Oral diseases

    pub_type: 历史文章,杂志文章,评审

    doi:10.1111/odi.12485

    authors: Park CM,Welbury R

    更新日期:2016-10-01 00:00:00

  • Hyperbaric oxygen therapy and osteonecrosis.

    abstract::Osteonecrosis of the jaw may be caused by radiation, medication, or infection. Optimal therapy requires a multimodal approach that combines surgery with adjuvant treatments. This review focuses on the use of adjunctive hyperbaric oxygen therapy for this condition. In addition to evidence regarding the basic and clinic...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.12489

    authors: Ceponis P,Keilman C,Guerry C,Freiberger JJ

    更新日期:2017-03-01 00:00:00

  • Emerging and changing viral diseases in the new millennium.

    abstract::Most viral infections encountered in resource-rich countries are relatively trivial and transient with perhaps fever, malaise, myalgia, rash (exanthema) and sometimes mucosal manifestations (enanthema), including oral in some. However, the apparent benignity may be illusory as some viral infections have unexpected con...

    journal_title:Oral diseases

    pub_type: 杂志文章,评审

    doi:10.1111/odi.12356

    authors: Scully C,Samaranayake LP

    更新日期:2016-04-01 00:00:00

  • Proinflammatory cytokine levels in saliva before and after treatment of (erosive) oral lichen planus with dexamethasone.

    abstract:OBJECTIVE:To explore the potential of detecting the level of proinflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha), interleukin-1-alpha (IL-1-alpha), IL-6, and IL-8 in whole unstimulated saliva (WUS) in monitoring the therapeutic effects of topical dexamethasone on these salivary cytokines in subjects with...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2005.01165.x

    authors: Rhodus NL,Cheng B,Bowles W,Myers S,Miller L,Ondrey F

    更新日期:2006-03-01 00:00:00

  • Epithelioid hemangioendothelioma of the oral cavity.

    abstract:OBJECTIVE:To investigate the clinicopathological characteristics and biologic behaviour of epithelioid hemangioendothelioma in the oral cavity. MATERIALS AND METHODS:The clinical features and pathological findings of nine cases with intraoral epithelioid hemangioendothelioma were reviewed, including immunohistochemist...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2006.01281.x

    authors: Sun ZJ,Zhang L,Zhang WF,Chen XM,Lai FM,Zhao YF

    更新日期:2007-03-01 00:00:00

  • Evidence for local production of antibodies to auto and non-self antigens in periodontal disease.

    abstract:UNLABELLED:Autoimmune mechanisms may contribute to periodontal disease (PD) pathogenesis; autoantibody to collagen type 1 is produced at the periodontal site and local levels are found to be higher than in serum. OBJECTIVES:To find any evidence of autoimmune destruction in diseased periodontal tissues in patients with...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1046/j.1354-523x.2003.00961.x

    authors: Rajapakse PS,Dolby AE

    更新日期:2004-03-01 00:00:00

  • Morphology and chronology of diphyodont dentition in miniature pigs, Sus Scrofa.

    abstract:OBJECTIVE:There is little knowledge about the tooth replacement in large mammals. The aim of this study is to investigate the tooth replacement patterns in Chinese miniature pig (Sus Scrofa). MATERIALS AND METHODS:The developmental patterns of mandibular successional and additional teeth from Chinese miniature pig bef...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12126

    authors: Wang F,Xiao J,Cong W,Li A,Song T,Wei F,Xu J,Zhang C,Fan Z,Wang S

    更新日期:2014-05-01 00:00:00

  • The association between miR-499a polymorphism and oral squamous cell carcinoma progression.

    abstract:OBJECTIVE:To investigate the association of miR-499a genetic polymorphism with the risk of oral leukoplakia, oral submucous fibrosis (OSF), oral squamous cell carcinoma (OSCC), and clinicopathological outcomes of OSCC. METHODS:The genotyping of miR-499a T>C (rs3746444) using TagMan assay was conducted in two case-cont...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12241

    authors: Hou YY,Lee JH,Chen HC,Yang CM,Huang SJ,Liou HH,Chi CC,Tsai KW,Ger LP

    更新日期:2015-03-01 00:00:00

  • Viscosity and wettability of animal mucin solutions and human saliva.

    abstract:OBJECTIVE:The purpose of this study was to compare viscosity and wettability between animal mucin solutions and human saliva. MATERIALS AND METHODS:Human whole and glandular saliva, porcine gastric mucin, bovine submaxillary mucin, and a mucin-based saliva substitute were used. Viscosity was measured with a cone-and-p...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2006.01263.x

    authors: Park MS,Chung JW,Kim YK,Chung SC,Kho HS

    更新日期:2007-03-01 00:00:00

  • Nitric oxide synthesis and severity of human periodontal disease.

    abstract:UNLABELLED:The expression of the inducible nitric oxide synthase enzyme (iNOS) is a response to an inflammatory stimulus and produces a large amount of nitric oxide (NO), which may act as a cytotoxic molecule against the invading microorganism and may be related to both harmful and beneficial effects to tissues. OBJEC...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1034/j.1601-0825.2002.02852.x

    authors: Batista AC,Silva TA,Chun JH,Lara VS

    更新日期:2002-09-01 00:00:00

  • Diagnostic profiling of salivary exosomal microRNAs in oral lichen planus patients.

    abstract:OBJECTIVE:Oral lichen planus is a chronic inflammatory oral mucosal disease whose exact cause is unclear and which requires efficient diagnostic and therapeutic strategies. Identification of disease-specific biomarkers in saliva is an easy, quick, and non-invasive approach for molecular diagnosis. This study was design...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/odi.12374

    authors: Byun JS,Hong SH,Choi JK,Jung JK,Lee HJ

    更新日期:2015-11-01 00:00:00

  • Is erythematous candidiasis associated with advanced HIV disease?

    abstract:OBJECTIVES:A multicentre collaborative study by the London HIV and Dentistry Group failed to associate the presence of erythematous candidiasis (EC) with advanced HIV disease. Data from a study of the periodontal health of homosexual men attending a genito-urinary medicine clinic presented an opportunity to investigate...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.1997.tb00339.x

    authors: Robinson PG,Challacombe SJ,Sheiham A,Zakrzewska JM

    更新日期:1997-05-01 00:00:00

  • Dental panoramic radiographic evaluation in bisphosphonate-associated osteonecrosis of the jaws.

    abstract:OBJECTIVES:To determine the extent to which clinical and radiographic features of bisphosphonate-associated osteonecrosis of the jaw (BONJ) are correlated. DESIGN:Retrospective case review. METHODS:The records of 39 patients diagnosed with BONJ and examined by panoramic radiography were retrospectively evaluated. The...

    journal_title:Oral diseases

    pub_type: 杂志文章

    doi:10.1111/j.1601-0825.2008.01494.x

    authors: Treister N,Sheehy N,Bae EH,Friedland B,Lerman M,Woo S

    更新日期:2009-01-01 00:00:00