Dispatcher-assisted cardiopulmonary resuscitation. Validation of efficacy.

abstract：:Preservation of regional myocardial function, high-energy phosphate stores and ultrastructure were assessed in 28 canine hearts subjected to 2 hours of global ischemia at either 12 degrees C or 21 degrees C. The preservation achieved with a potassium arrest solution was simultaneously compared in the same heart with e...

journal_title：Circulation

authors： Johnson RG,Jacocks MA,Aretz TH,Geffin GA,O'Keefe DD,DeBoer LW,Guyton RA,Fallon JT,Daggett WM

更新日期：1982-08-01 00:00:00

abstract：:To determine the effects of coronary angioplasty on coronary flow reserve (CFR), we studied 32 patients before and immediately after single-vessel coronary angioplasty and 31 patients evaluated late after angioplasty (7.5 +/- 1.2 months, mean +/- SEM). The geometry (percent area stenosis and minimal cross-sectional ar...

journal_title：Circulation

authors： Wilson RF,Johnson MR,Marcus ML,Aylward PE,Skorton DJ,Collins S,White CW

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Macrophages contribute to the progression and acute complications of atherosclerosis. Macrophage imaging may serve as a biomarker to identify subclinical inflamed lesions, to predict future risk, and to aid in the assessment of novel therapies. METHODS AND RESULTS:To test the hypothesis that nanoparticle-en...

journal_title：Circulation

authors： Morishige K,Kacher DF,Libby P,Josephson L,Ganz P,Weissleder R,Aikawa M

更新日期：2010-10-26 00:00:00

abstract：BACKGROUND:Assessment of systemic right ventricular (RV) function is a key point in the follow-up of patients with transposition of the great arteries (TGA). Current echocardiographic assessment of RV function is at best an estimate, and cardiac magnetic resonance (CMR) is considered the gold standard. However, this te...

journal_title：Circulation

authors： Salehian O,Schwerzmann M,Merchant N,Webb GD,Siu SC,Therrien J

更新日期：2004-11-16 00:00:00

abstract：BACKGROUND:Long-term survival after acute kidney injury (AKI) is poorly studied. We report the relationship between long-term mortality and AKI with small changes in serum creatinine during hospitalization after various cardiothoracic surgery procedures. METHODS AND RESULTS:This was a retrospective study of 2973 patie...

journal_title：Circulation

authors： Hobson CE,Yavas S,Segal MS,Schold JD,Tribble CG,Layon AJ,Bihorac A

更新日期：2009-05-12 00:00:00

abstract：BACKGROUND:The CAPRICORN trial has shown that carvedilol improved outcome in patients with left ventricular dysfunction after acute myocardial infarction treated with ACE inhibitors. The aim of this substudy was to determine the effects of carvedilol on left ventricular remodeling in this patient group. METHODS AND RE...

journal_title：Circulation

authors： Doughty RN,Whalley GA,Walsh HA,Gamble GD,López-Sendón J,Sharpe N,CAPRICORN Echo Substudy Investigators.

更新日期：2004-01-20 00:00:00

abstract：BACKGROUND:Residual mural thrombus on severely damaged arterial wall is very thrombogenic. We tested the hypothesis that direct thrombin inhibition will block thrombus growth on fresh thrombus better than indirect thrombin inhibition, cyclooxygenase inhibition, or both. METHODS AND RESULTS:A fresh mural thrombus was f...

journal_title：Circulation

authors： Meyer BJ,Badimon JJ,Mailhac A,Fernández-Ortiz A,Chesebro JH,Fuster V,Badimon L

更新日期：1994-11-01 00:00:00

abstract：:In 15 of 126 (12%) patients with truncus arteriosus who were catheterized at the Mayo Clinic from 1967 through 1975, natural agenesis of one pulmonary artery was present. Ten truncus patients with either natural or acquired absence of one pulmonary artery have undergone definitive operation. The criteria for operabili...

journal_title：Circulation

authors： Mair DD,Ritter DG,Danielson GK,Wallace RB,McGoon DC

更新日期：1977-04-01 00:00:00

abstract：:To determine whether multiple lead precordial electrocardiographic recordings offer an improved index for noninvasive estimation of left ventricular hemodynamic function and segmental dyssynergy, precordial mapping was performed in patients with anterior myocardial infarction, and the number of pathologic Q waves (gre...

journal_title：Circulation

authors： Awan NA,Miller RR,Vera Z,Janzen DA,Amsterdam EA,Mason DT

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:Fibrinogen has been identified as an independent risk factor for cardiovascular disease and associated with traditional cardiovascular risk factors. Also, the role of elevated fibrinogen in thrombosis suggests that it may be on the causal pathway for certain risk factors to exert their effect. These associat...

journal_title：Circulation

authors： Stec JJ,Silbershatz H,Tofler GH,Matheney TH,Sutherland P,Lipinska I,Massaro JM,Wilson PF,Muller JE,D'Agostino RB Sr

更新日期：2000-10-03 00:00:00

abstract：BACKGROUND:Mendelian randomization studies have highlighted that lipoprotein(a) [Lp(a)] was associated with calcific aortic valve disease (CAVD). Lp(a) transports oxidized phospholipids with a high content in lysophosphatidylcholine. Autotaxin (ATX) transforms lysophosphatidylcholine into lysophosphatidic acid. We hypo...

journal_title：Circulation

authors： Bouchareb R,Mahmut A,Nsaibia MJ,Boulanger MC,Dahou A,Lépine JL,Laflamme MH,Hadji F,Couture C,Trahan S,Pagé S,Bossé Y,Pibarot P,Scipione CA,Romagnuolo R,Koschinsky ML,Arsenault BJ,Marette A,Mathieu P

更新日期：2015-08-25 00:00:00

abstract：BACKGROUND:Previous studies have reported an association between chronic Helicobacter pylori infection and ischemic heart disease. However, it is not clear whether this association is really due to the virulence of the bacterium or is merely the result of confounding factors (in particular, age and social class). METH...

journal_title：Circulation

authors： Pasceri V,Cammarota G,Patti G,Cuoco L,Gasbarrini A,Grillo RL,Fedeli G,Gasbarrini G,Maseri A

更新日期：1998-05-05 00:00:00

abstract：BACKGROUND:This study was performed to determine whether chronic cocaine abuse is associated with left ventricular hypertrophy in humans. METHODS AND RESULTS:A consecutive series of 40 chronic cocaine abusers 23-44 years old who were enrolled in an inpatient drug rehabilitation program were considered for the study. S...

journal_title：Circulation

authors： Brickner ME,Willard JE,Eichhorn EJ,Black J,Grayburn PA

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:This experiment sought to determine the effects of fish oil on superoxide anion production in the myocardium and coronary arteries of atherosclerotic monkeys. Recent evidence indicates that dietary supplementation with fish oil preserves normal vasomotion of atherosclerotic coronary arteries and reduces dama...

journal_title：Circulation

authors： Supari F,Ungerer T,Harrison DG,Williams JK

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:We sought to define the factors associated with the occurrence of stroke and systemic embolism in a large, international atrial fibrillation (AF) trial. METHODS AND RESULTS:In ROCKET AF (Rivaroxaban Once-daily, oral, direct factor Xa inhibition Compared with vitamin K antagonism for prevention of stroke and...

journal_title：Circulation

authors： Piccini JP,Stevens SR,Chang Y,Singer DE,Lokhnygina Y,Go AS,Patel MR,Mahaffey KW,Halperin JL,Breithardt G,Hankey GJ,Hacke W,Becker RC,Nessel CC,Fox KA,Califf RM,ROCKET AF Steering Committee and Investigators.

更新日期：2013-01-15 00:00:00

abstract：BACKGROUND:Cigarette smoking has been recognized as an important risk factor for cardiovascular disease in men and women. Whether the increased risk results from an atherogenic effect of smoking is still debated. We examined the relation between cigarette smoking and atherosclerotic changes in the abdominal aorta. MET...

journal_title：Circulation

authors： Witteman JC,Grobbee DE,Valkenburg HA,van Hemert AM,Stijnen T,Hofman A

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Five years ago, we described a specific ECG pattern of right bundle-branch block and ST-segment elevation in leads V1 through V3 associated with sudden death in patients without demonstrable structural heart disease. Information on long-term outcome has become available due to pooled data on a large cohort o...

journal_title：Circulation

authors： Brugada J,Brugada R,Brugada P

更新日期：1998-02-10 00:00:00

abstract：BACKGROUND:Cardiac ischemia on the ambulatory ECG (AECG) and/or on the exercise treadmill test (ETT) is associated with an increased risk of adverse outcome. Myocardial revascularization more often suppresses cardiac ischemia than does medical management alone. However, few studies have compared the effects of percutan...

journal_title：Circulation

authors： Bourassa MG,Knatterud GL,Pepine CJ,Sopko G,Rogers WJ,Geller NL,Dyrda I,Forman SA,Chaitman BR,Sharaf B

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Chronic heart failure is associated with endothelial dysfunction including impaired endothelium-mediated, flow-dependent dilation (FDD). Since endothelial function is thought to play an important role in coordinating tissue perfusion and modulating arterial compliance, interventions to improve endothelial dy...

journal_title：Circulation

authors： Hornig B,Maier V,Drexler H

更新日期：1996-01-15 00:00:00

abstract：:To determine how survival and clinical status were related to left ventricular (LV) size and systolic function after mitral valve replacement, 104 patients (48 mitral regurgitation [MR], 33 mitral stenosis [MS], and 23 MS/MR) with isolated mitral valve replacement were evaluated before and after surgery. Preoperative ...

journal_title：Circulation

authors： Crawford MH,Souchek J,Oprian CA,Miller DC,Rahimtoola S,Giacomini JC,Sethi G,Hammermeister KE

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:In humans, angiotensin converting enzyme (ACE) inhibition attenuates the vasoconstriction induced by sympathetic stimulation in a number of peripheral districts. Whether this is also the case in the coronary circulation is unknown, however. METHODS AND RESULTS:In nine normotensive patients with angiographic...

journal_title：Circulation

authors： Perondi R,Saino A,Tio RA,Pomidossi G,Gregorini L,Alessio P,Morganti A,Zanchetti A,Mancia G

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:Connexin (Cx)40 and Cx45 are the major protein subunits of gap junction channels in the conduction system of mammals. To determine the role of Cx40, we correlated cardiac activation with Connexin distribution in normal and Cx40-deficient mice hearts. METHODS AND RESULTS:Epicardial and septal activation was ...

journal_title：Circulation

authors： van Rijen HV,van Veen TA,van Kempen MJ,Wilms-Schopman FJ,Potse M,Krueger O,Willecke K,Opthof T,Jongsma HJ,de Bakker JM

更新日期：2001-03-20 00:00:00

abstract：:Hemodynamic and clinical evaluations of 123 patients with acute myocardial infarction were performed during the first hour of admission to the hospital. In the 123 patients, the right atrial pressure was less than 10 mm Hg in 49 patients, the right atrial oxygen saturation was less than 70% in 97 patients, the arterio...

journal_title：Circulation

authors： Ramo BW,Myers N,Wallace AG,Starmer F,Clark DO,Whalen RE

更新日期：1970-10-01 00:00:00

abstract：:Prospective data was recorded on 217 percutaneous transluminal angioplasty (PTA) procedures performed in the superficial femoral and popliteal arteries over an 8-year period. After the initial procedure, patients were followed with serial noninvasive studies and, in 71 patients, repeat angiography. The mean follow-up ...

journal_title：Circulation

authors： Capek P,McLean GK,Berkowitz HD

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Patients with acute ischemic right ventricular dysfunction often develop hemodynamic compromise, yet most manifest spontaneous early clinical improvement and later recovery of global right ventricular performance. This study was designed to delineate the determinants of right ventricular performance followin...

journal_title：Circulation

authors： Laster SB,Shelton TJ,Barzilai B,Goldstein JA

更新日期：1993-08-01 00:00:00

abstract：:In our approach to dynamic cardiomyoplasty, which consists of wrapping a skeletal muscle around the heart and stimulating the former in synchrony with heart contractions to augment ventricular contractility, we have transferred a latissimus dorsi muscle flap to the heart by way of a partial resection of the second rib...

journal_title：Circulation

authors： Chachques JC,Grandjean P,Schwartz K,Mihaileanu S,Fardeau M,Swynghedauw B,Fontaliran F,Romero N,Wisnewsky C,Perier P

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Identification of genes that are specifically activated in restenosis lesions after percutaneous transluminal angioplasty represents a necessary step toward molecular manipulation designed to inhibit cellular proliferation responsible for such lesions. Whereas quiescent smooth muscle cells (contractile pheno...

journal_title：Circulation

authors： Leclerc G,Isner JM,Kearney M,Simons M,Safian RD,Baim DS,Weir L

更新日期：1992-02-01 00:00:00

abstract：:Digitalis has been shown to improve the impaired ventricular function associated with coronary artery disease as well as to increase myocardial oxygen consumption and produce coronary vasoconstriction. To elucidate the net result of these contrasting effects, six patients with coronary artery disease and left ventricu...

journal_title：Circulation

authors： Vogel R,Kirch D,LeFree M,Frischknecht J,Steele P

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:The sarcomeric protein titin is a molecular spring responsible for passive tension and restoring forces of cardiomyocytes. Extension of titin as a function of sarcomere length (SL) has been studied in rodents, which predominantly express the smaller, stiffer N2B titin isoform. Large mammals coexpress roughly...

journal_title：Circulation

authors： Lewinter MM,Popper J,McNabb M,Nyland L,Bell SB,Granzier H

更新日期：2010-02-16 00:00:00

abstract：BACKGROUND:Thioredoxin 2 (Trx2) is a key mitochondrial protein that regulates cellular redox and survival by suppressing mitochondrial reactive oxygen species generation and by inhibiting apoptosis stress kinase-1 (ASK1)-dependent apoptotic signaling. To date, the role of the mitochondrial Trx2 system in heart failure ...

journal_title：Circulation

authors： Huang Q,Zhou HJ,Zhang H,Huang Y,Hinojosa-Kirschenbaum F,Fan P,Yao L,Belardinelli L,Tellides G,Giordano FJ,Budas GR,Min W

更新日期：2015-03-24 00:00:00