Impact of pre-gestational and gestational diabetes mellitus on the expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 in human term placenta.

abstract：PURPOSE:To evaluate whether losartan is able to induce beige adipocytes formation, focusing on the thermogenic gene expression and adipocyte remodeling in the subcutaneous white adipose tissue of diet-induced obese mice. METHODS:Male C57BL/6 mice received a control diet (10% energy as lipids) or a high-fat diet (50% e...

journal_title：Endocrine

authors： Graus-Nunes F,Rachid TL,de Oliveira Santos F,Barbosa-da-Silva S,Souza-Mello V

更新日期：2017-03-01 00:00:00

abstract：:Acromegaly is a debilitating disease usually caused by a growth-hormone secreting pituitary adenoma. Therapeutic goals include improvement of symptoms, reduction in tumor mass, biochemical normalization, and preservation of pituitary function. Treatment options include transsphenoidal surgery, radiation, and pharmacot...

journal_title：Endocrine

authors： Danoff A,Kleinberg D

更新日期：2003-04-01 00:00:00

abstract：:This study examined the interrelationship between transforming growth factor-beta1 (TGF-beta1) and 17beta-estradiol (E2) in the regulation of growth plate chondrocytes. To determine whether TGF-beta1 modulates chondrocyte response to E2, we used cells isolated from the resting zone (RC) and growth zone (GC) of costoch...

journal_title：Endocrine

authors： Nasatzky E,Grinfeld D,Boyan BD,Dean DD,Ornoy A,Schwartz Z

更新日期：1999-12-01 00:00:00

abstract：:Previous evidence supports the view that insulin, as well as insulin like growth factor-1 (IGF-1) provides neurotropic support for neurons in the central nervous system (CNS) and peripheral nervous system (PNS). In the present study we evaluated the effects of the intravenous infusion of IGF-1 on both necrosis and apo...

journal_title：Endocrine

authors： Rizk NN,Myatt-Jones J,Rafols J,Dunbar JC

更新日期：2007-02-01 00:00:00

abstract：:The oncogenic activation of the rearranged during transfection (RET) proto-oncogene has a main role in the pathogenesis of medullary thyroid cancer (MTC). Several lines of evidence suggest that RET function could be influenced by cyclic AMP (cAMP)-dependent protein kinase A (PKA) activity. We evaluated the in vitro an...

journal_title：Endocrine

authors： Dicitore A,Grassi ES,Caraglia M,Borghi MO,Gaudenzi G,Hofland LJ,Persani L,Vitale G

更新日期：2016-01-01 00:00:00

abstract：:The aim is to study the association of estrogen receptor α (ERα) and estrogen receptor β (ERβ) gene polymorphisms and diplotypes with ovarian response to follicle-stimulating hormone (FSH) stimulation and the hormone levels [FSH, luteinizing hormone (LH), E2] at the third day of the menstrual cycle. Three hundred wome...

journal_title：Endocrine

authors： Lazaros L,Pamporaki C,Vlahos N,Takenaka A,Kitsou C,Kosmas I,Sofikitis N,Stefos T,Zikopoulos K,Hatzi E,Georgiou I

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:Mutant hypothyroid mouse models have recently shown that thyroid hormone is critical for skeletal development during an important prepubertal growth period. Additionally, thyroid hormone negatively regulates total body fat, consistent with the well-established effects of thyroid hormone on energy and fat metabo...

journal_title：Endocrine

authors： Lindsey RC,Mohan S

更新日期：2017-04-01 00:00:00

abstract：:Initiation and maintenance of labor in humans is associated with an increase in prostaglandin synthesis by intrauterine tissues. The objective of the present study was to characterize the distribution of membrane-bound PGES (mPGES) protein and mPGES mRNA in human placenta, fetal membranes, and decidua at term and to d...

journal_title：Endocrine

authors： Alfaidy N,Sun M,Challis JR,Gibb W

更新日期：2003-04-01 00:00:00

abstract：:The familial forms of non-medullary thyroid carcinoma (FNMTC) represent approximately 5 % of thyroid neoplasms. Nine FNMTC susceptibility loci have been mapped; however, only the DICER1 and SRGAP1 susceptibility genes have been identified. The transcription factors NKX2-1, FOXE1, PAX8, and HHEX are involved in the mor...

journal_title：Endocrine

authors： Pereira JS,da Silva JG,Tomaz RA,Pinto AE,Bugalho MJ,Leite V,Cavaco BM

更新日期：2015-05-01 00:00:00

abstract：:Recent animal studies support close associations of Periostin with hepatosteatosis and steatohepatitis. This study is to evaluate the role of serum periostin in non-alcoholic fatty liver disease (NAFLD). A hospital-based age-/sex-matched case-control study was conducted. Binary logistic regression and receiver operati...

journal_title：Endocrine

authors： Zhu JZ,Zhu HT,Dai YN,Li CX,Fang ZY,Zhao DJ,Wan XY,Wang YM,Wang F,Yu CH,Li YM

更新日期：2016-01-01 00:00:00

abstract：:Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are relatively rare and heterogenous malignancies. Recent advances in histopathological classification according to the anatomical site of origin, proliferation rate, and extend of the disease have created a valid and powerful tool for the prognostic stratificati...

journal_title：Endocrine

authors： Alexandraki KI,Kaltsas G

更新日期：2012-02-01 00:00:00

abstract：:Ames dwarf mice have primary deficiency of prolactin (PRL), growth hormone (GH), and thyroid-stimulating hormone (TSH), and live considerably longer than normal animals from the same line. In view of the documented effects of GH, PRL, and thyroid hormones on lean and fat body mass and skeletal growth, and the suspecte...

journal_title：Endocrine

authors： Heiman ML,Tinsley FC,Mattison JA,Hauck S,Bartke A

更新日期：2003-02-01 00:00:00

abstract：PURPOSE:To evaluate the reliability of intermittent intraoperative neuromonitoring (I-IONM) through recurrent laryngeal nerve (RLN) stimulation and laryngeal palpation in predicting postoperative vocal cord palsy and to examine the reliability of this technique in providing useful information in the decision to perform...

journal_title：Endocrine

authors： Cavicchi O,Burgio L,Cioccoloni E,Piccin O,Macrì G,Schiavon P,Dionigi G

更新日期：2018-12-01 00:00:00

abstract：:Environmental factors have been implicated in the development of autoimmune thyroid disease (AITD). Anti-Saccaromyces Cerevisiae Antibodies (ASCA) were shown to be elevated in several autoimmune diseases. The aim of the study was to determine ASCA levels and their relationship with thyroid autoantibodies in patients w...

journal_title：Endocrine

authors： Yazıcı D,Aydın SZ,Yavuz D,Tarçın O,Deyneli O,Direskeneli H,Akalın S

更新日期：2010-10-01 00:00:00

abstract：:Several studies have demonstrated an imbalance between free radicals and the antioxidative system in individuals with thyroid dysfunction. However, oxidative stress has not been evaluated in patients with thyroidectomy and thyroparathyroidectomy, who are under replacement therapy. The objective of this study was to ev...

journal_title：Endocrine

authors： Kaçmaz M,Atmaca M,Arslan A,Demir H,Özbay MF

更新日期：2015-02-01 00:00:00

abstract：:Circadian rhythmicity is affected in obese subjects. This article analyzes the effect of a high-fat diet (35% fat) on 24-h changes circulating prolactin, luteinizing hormone (LH), testosterone, corticosterone, thyroid-stimulating hormone (TSH) and glucose, and pineal melatonin content, in rats. When body weight of rat...

journal_title：Endocrine

authors： Cano P,Jiménez-Ortega V,Larrad A,Reyes Toso CF,Cardinali DP,Esquifino AI

更新日期：2008-04-01 00:00:00

abstract：:Thioredoxin-interacting protein (TXNIP) is a known important regulatory protein of islet β-cell biology and function, but the detailed mechanism is not clear. Autophagy plays a pivotal role in maintaining cellular homoeostasis. This study aimed to elucidate the influence of TXNIP on the autophagy of β-cell. In this st...

journal_title：Endocrine

authors： Deng W,Li Y,Ren Z,He Q,Jia Y,Liu Y,Zhang W,Gan X,Liu D

更新日期：2020-12-01 00:00:00

abstract：:Erectile dysfunction (ED) is commonly associated with risk factors for cardiovascular disease, including diabetes. The prevalence of ED in diabetic patients is high--about 75% of diabetic men 60 yr of age or older had ED in one study. Endothelial dysfunction, accelerated atherosclerosis, and diabetic neuropathy likely...

journal_title：Endocrine

authors： Kloner RA

更新日期：2004-03-01 00:00:00

abstract：PURPOSE:Metabolic syndrome (MetS) is a constellation of clinical factors that indicates elevated risk of diabetes. It is diagnosed based on three or more abnormalities in its components. This does not take into account that MetS can likely present as a continuum of risk. We aim to develop a MetS severity score and asse...

journal_title：Endocrine

authors： Low S,Khoo KCJ,Wang J,Irwan B,Sum CF,Subramaniam T,Lim SC,Wong TKM

更新日期：2019-07-01 00:00:00

abstract：:Follicle-stimulating hormone (FSH) is a key stimulant for the development of the ovarian follicle, while luteinizing hormone (LH) plays a major role in triggering ovulation and luteinization. Both FSH and LH are glycoprotein hormones that share the same alpha subunit but bind to specific seven transmembrane-domain G c...

journal_title：Endocrine

authors： Friedmann S,Dantes A,Amsterdam A

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVES:Publications suggesting that thyroid nodule might be associated with insulin resistance and metabolic syndrome are quite interesting. There is a need for studies assessing the relationship between nodule presence and cardiovascular risk in individuals with non-functioning nodular goiter. The purpose of the p...

journal_title：Endocrine

authors： Aydoğan Y,Altay M,Ünsal O,Kaplanoğlu V,Çağır Y,Yıldız C,Beyan E,Ramadan SU

更新日期：2018-11-01 00:00:00

abstract：:Riedel's thyroiditis (RT) is a rare type of chronic thyroiditis of unproven etiology and definite treatment. It can be associated with retroperitoneal, mediastinal, orbital, and hepatic fibrosis. Symptoms arise mainly due to compression of neighboring structures. Surgery is usually required for a definite diagnosis an...

journal_title：Endocrine

authors： Erdoğan MF,Anil C,Türkçapar N,Ozkaramanli D,Sak SD,Erdoğan G

更新日期：2009-06-01 00:00:00

abstract：:Interleukin-6 (IL-6) and tumor necrosis factor (TNF) are secreted by rat adrenal zona glomerulosa cells. Serotonin increases the release of aldosterone, corti-costerone, and cortisol from the adrenal cortex. Therefore, the effects of serotonin on IL-6 and TNF release from rat adrenal zona glomerulosa cells were invest...

journal_title：Endocrine

authors： Ritchie PK,Knight HH,Ashby M,Judd AM

更新日期：1996-12-01 00:00:00

abstract：:Detection of connexin (Cx) proteins has been used as an indicator of the presence of structural and functional gap junctions in tissues. To examine the role of gap junctions during follicular growth and atresia, the presence of three major connexins, Cx43, Cx32, and Cx26, was evaluated in bovine ovaries by using immun...

journal_title：Endocrine

authors： Johnson ML,Redmer DA,Reynolds LP,Grazul-Bilska AT

更新日期：1999-02-01 00:00:00

abstract：PURPOSE:Parathyroid carcinoma (PCa) is a rare endocrine malignancy with poor prognosis and is often difficult to accurately diagnose both before and after surgery. Dysregulated microRNA (miRNA) levels have been identified in PCa using a limited number of samples. The aim of the present study was to verify a group of mi...

journal_title：Endocrine

authors： Hu Y,Zhang X,Cui M,Su Z,Wang M,Liao Q,Zhao Y

更新日期：2018-05-01 00:00:00

abstract：:The expression and activities of constitutive nitric oxide synthase (cNOS) and inducible nitric oxide synthase (iNOS) in relation to insulin and glucagon secretory mechanisms were investigated in islets isolated from rats subjected to total parenteral nutrition (TPN) for 10 d. TPN is known to result in significantly i...

journal_title：Endocrine

authors： Salehi A,Ekelund M,Henningsson R,Lundquist I

更新日期：2001-11-01 00:00:00

abstract：:This study was performed to ascertain whether a relationship exists between thyroid function and blood pressure in school-aged Chinese subjects without overt thyroid disease. A cross-sectional survey of 880 subjects (541 females and 339 males) aged 7-18 years in Bengbu, Anhui province was conducted. The investigation,...

journal_title：Endocrine

authors： Chen H,Xi Q,Zhang H,Song B,Liu X,Mao X,Li J,Shen H,Tang W,Zhang J,Wang Z,Duan Y,Liu C

更新日期：2012-02-01 00:00:00

abstract：:To evaluate the role of central subfield thickness (CST), cube average thickness (CAT), and cube volume (CV) as imaging biomarkers for severity of diabetic retinopathy within the ETDRS-based grades of retinopathy using spectral domain optical coherence tomography (SD-OCT). This study aims to evaluate the role of macul...

journal_title：Endocrine

authors： Saxena S,Caprnda M,Ruia S,Prasad S,Ankita,Fedotova J,Kruzliak P,Krasnik V

更新日期：2019-12-01 00:00:00

abstract：:Strict glucose control is a well-proven therapeutic approach for peripheral neuropathies in patients with diabetes. Alpha lipoic acid (ALA) has also been accepted as a therapeutic agent for diabetic peripheral neuropathy (DPN) in the respect of pathogenesis. However, the potential of ALA as a treatment for DPN in comp...

journal_title：Endocrine

authors： Lee KA,Lee NY,Park TS,Jin HY

更新日期：2018-07-01 00:00:00

abstract：:To report on the incidence and use of kelp among patients with thyroid cancer. Data were collected using a web-based online anonymous survey under Institutional Review Board approval from Boston University. This report is based on 27 responses from subjects with thyroid cancer who use kelp. Demographic factors and com...

journal_title：Endocrine

authors： Rosen JE,Gardiner P,Saper RB,Pearce EN,Hammer K,Gupta-Lawrence RL,Lee SL

更新日期：2014-05-01 00:00:00