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Marine sponge alkaloids as a source of anti-bacterial adjuvants.

Abstract：

:Novel approaches that do not rely upon developing microbicidal compounds are sorely needed to combat multidrug resistant (MDR) bacteria. The potential of marine secondary metabolites to serve as a source of non-traditional anti-bacterial agents is demonstrated by showing that pyrrole-imidazole alkaloids inhibit biofilm formation and suppress antibiotic resistance.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Melander RJ,Liu HB,Stephens MD,Bewley CA,Melander C

doi

10.1016/j.bmcl.2016.11.018

subject

Has Abstract

pub_date

2016-12-15 00:00:00

pages

5863-5866

issue

24

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(16)31159-3

journal_volume

26

pub_type

杂志文章

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