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Electrochemical and esr spin trap studies of a new iron tetra-catecholamide complex.

Abstract：

:A new siderophore, N5,N6-thiodipropanoyl-bis[N1,N10-bis(2,3-dihydroxy benzoyl-spermidine)]-Fe (III) complex or H2LFe has been synthesised. The reaction of the reduced form of this complex with dioxygen has been investigated through electrochemical study and revealed the formation of a new species assumed to be H2O2. This species has been confirmed by esr spectroscopy using the diamagnetic compound 5-deutero-2,2,5-trimethylpyrrolidine-1-hydroxyl as spin trap. The resulting persistent radical is 5-deutero-2,2,5-trimethylpyrrolidine-1-yloxy (aN = 16.58 G, aD = 3.49 G).

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Cheraïti N,Brik ME,Keita B,Nadjo L,Gaudemer A

doi

10.1016/s0960-894x(99)00371-6

subject

Has Abstract

pub_date

1999-08-16 00:00:00

pages

2315-20

issue

16

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(99)00371-6

journal_volume

9

pub_type

杂志文章

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