Abstract:
:Triterpene derivatives were analyzed for anti-HIV-1 activity and for cellular toxicity. Betulinic aldehyde, betulinic nitrile, and morolic acid derivatives were identified to have anti-HIV-1 activity. These derivatives inhibit a late step in virus replication, likely virus maturation.
journal_name
Bioorg Med Chem Lettjournal_title
Bioorganic & medicinal chemistry lettersauthors
Dorr CR,Yemets S,Kolomitsyna O,Krasutsky P,Mansky LMdoi
10.1016/j.bmcl.2010.10.078subject
Has Abstractpub_date
2011-01-01 00:00:00pages
542-5issue
1eissn
0960-894Xissn
1464-3405pii
S0960-894X(10)01539-8journal_volume
21pub_type
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