Abstract:
:A one step synthesis of fluorescent 8-aryl-(7-deazaguanines) has been accomplished. Probes exhibit blue to green high quantum yield fluorescence in a variety of organic and aqueous solutions, high extinction coefficients, and large Stokes shifts often above 100 nm. The probes are highly cell permeable, and exhibit stable bright fluorescence once intracellular; therefore are suited to the design of biosensors.
journal_name
Bioorg Med Chem Lettjournal_title
Bioorganic & medicinal chemistry lettersauthors
Dhimitruka I,Eubank TD,Gross AC,Khramtsov VVdoi
10.1016/j.bmcl.2015.08.054subject
Has Abstractpub_date
2015-10-15 00:00:00pages
4593-6issue
20eissn
0960-894Xissn
1464-3405pii
S0960-894X(15)30006-8journal_volume
25pub_type
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