Prediction of Massive Transfusion in Trauma.

abstract：:This article reviews principles in the rational use of antibiotics in sepsis and septic shock and presents evidence-based recommendations for optimal antibiotic therapy. Every patient with sepsis and septic shock must be evaluated at presentation before the initiation of antibiotic therapy. However, in most situations...

journal_title：Critical care clinics

authors： Kumar A

更新日期：2009-10-01 00:00:00

abstract：:Fluid creep is the term applied to a burn resuscitation, which requires more fluid than predicted by standard formulas. Fluid creep is common today and is linked to several serious edema-related complications. Increased fluid requirements may accompany the appropriate resuscitation of massive injuries but dangerous fl...

journal_title：Critical care clinics

authors： Saffle JR

更新日期：2016-10-01 00:00:00

abstract：:Meningococcemia is notorious for evasion of the host immune system and its rapid progression to fulminant disease, and serves as a unique model for pediatric sepsis. Illness severity is determined by complex interplays among host, pathogen, and environment. The inflammatory host response, including proinflammatory and...

journal_title：Critical care clinics

authors： Boeddha NP,Bycroft T,Nadel S,Hazelzet JA

更新日期：2020-04-01 00:00:00

abstract：:Approximately 12,000 Americans suffer traumatic spinal cord injuries each year. This article discusses the management of their neurologic, respiratory, cardiovascular, gastroenterologic, and genitourinary complications in the critical care setting. ...

journal_title：Critical care clinics

authors： McVicar JP,Luce JM

更新日期：1986-10-01 00:00:00

abstract：:Extracorporeal life support is a modified form of cardiopulmonary bypass. Experience in extracorporeal membrane oxygenation (ECMO) has come largely from the neonatal population. Most centers have transitioned the ECMO pumps from roller pumps to centrifugal technology. Modes of support include venovenous for respirator...

journal_title：Critical care clinics

authors： Jenks CL,Raman L,Dalton HJ

更新日期：2017-10-01 00:00:00

abstract：:To be in respiratory distress is to be anxious. To be mechanically ventilated is to be grossly uncomfortable at best. To undergo weaning in the presence of possible severe respiratory compromise, again, inevitably is anxiety provoking. Assessment of the contributing causes of agitation is essential if patients are to ...

journal_title：Critical care clinics

authors： McCartney JR,Boland RJ

更新日期：1994-10-01 00:00:00

abstract：:Summarizing the mission of the ICU, the institution directive board and the unit director must generate a structure, proceedings criteria, management, and analysis of results capable of providing satisfactory care. Furthermore, they must take into account each organizational aspect that is necessary to offer an approp...

journal_title：Critical care clinics

authors： Gallesio AO,Ceraso D,Palizas F

更新日期：2006-07-01 00:00:00

abstract：:In pediatric trauma care, many long-held tenets of management have been revised. This article reviews the latest advances in pediatric trauma care, particularly in the areas of resuscitation and management of thoracic and abdominal injuries. The final topic is a discussion of what the intensivist and surgeon must know...

journal_title：Critical care clinics

authors： Garcia VF,Brown RL

更新日期：2003-07-01 00:00:00

abstract：:The availability, portability, safety, and other features of ultrasound have ushered this relatively new imaging modality into the everyday clinical practice of multiple disciplines. Features unique to ultrasound lend this imaging modality the opportunity for extensive use in the ICU. A review of its uses in this capa...

journal_title：Critical care clinics

authors： Beagle GL

更新日期：2000-01-01 00:00:00

abstract：:The proliferation of methicillin-resistant Staphylococcus aureus (MRSA) and the severity of nosocomial critical care infections necessitate the development of viable alternative therapies. An increase in the tolerance of MRSA to the activity of vancomycin and to the associated suboptimal therapeutic measures is of par...

journal_title：Critical care clinics

authors： Alder J

更新日期：2008-04-01 00:00:00

abstract：:Management of the cardiac transplant recipient includes careful titration of inotropes and vasopressors. Recipient pulmonary hypertension and ventilatory status must be optimized to prevent allograft right ventricular failure. Vasoplegia, coagulopathy, arrhythmias, and renal dysfunction also require careful management...

journal_title：Critical care clinics

authors： Rabin J,Kaczorowski DJ

更新日期：2019-01-01 00:00:00

abstract：:This article provides an overview of some of the current issues involved in sedation and anxiolysis in the intensive care unit. The problems involved in trying to monitor sedation levels are discussed, as are some of the newer options available for physiologic monitoring of the central nervous system. The problem of a...

journal_title：Critical care clinics

authors： Lowson SM,Sawh S

更新日期：1999-01-01 00:00:00

abstract：:This article identifies the key challenges facing critical care practitioners in Africa. As a continent with a large proportion of the poorest countries and a plethora of unique diseases that place large demands for critical resources, the provision of care is largely in the context of severely constrained human and m...

journal_title：Critical care clinics

authors： Bhagwanjee S

更新日期：2006-07-01 00:00:00

abstract：:This article documents the role of hypothalamic hypothyroidism and decreased T4-->T3 conversion as the cause of low T4 and T3 in non-thyroidal illness syndrome (NTIS). This article also presents the arguments for administration of replacement triiodothyronine (T3) and thyroxine (T4) hormone in patients who have NTIS. ...

journal_title：Critical care clinics

authors： De Groot LJ

更新日期：2006-01-01 00:00:00

abstract：:Acute coronary syndrome is a major health problem affecting approximately 1.5 million individuals a year. Early diagnosis and appropriate evidence-based therapies improve clinical outcomes significantly. Current data suggest that an early invasive therapy may improve intermediate-term and long-term outcomes, particula...

journal_title：Critical care clinics

authors： Bhatheja R,Mukherjee D

更新日期：2007-10-01 00:00:00

abstract：:Renal failure continues to cause a major burden of morbidity and mortality in both its acute and chronic forms, regardless of advances in current renal replacement therapies. A bioartificial kidney that includes a conventional dialysis filter and a renal tubule assist device containing approximately 10(8) renal proxim...

journal_title：Critical care clinics

authors： Tiranathanagul K,Eiam-Ong S,Humes HD

更新日期：2005-04-01 00:00:00

abstract：:Infection and/or sepsis biomarkers should help to make the diagnosis and thus initiate therapy earlier, help to differentiate between infectious and sterile inflammation, allow the use of more-specific antimicrobials, shorten the time of antimicrobial use, and ideally identify distinct phenotypes that may benefit from...

journal_title：Critical care clinics

authors： Reinhart K,Meisner M

更新日期：2011-04-01 00:00:00

abstract：:It is important that educators in the intensive care unit (ICU) provide physicians in training with the guidance and experience requisite in developing foundational skills in value-based medical practice. This article discusses the underlying philosophy of ethically based medical decision making and describes the comp...

journal_title：Critical care clinics

authors： Crausman RS,Armstrong JD 2nd

更新日期：1996-01-01 00:00:00

abstract：:The recent development of valid and reliable assessment tools to monitor agitation, sedation, analgesia, and delirium in the ICU represents an essential first step in the provision of patient comfort and the development of preferred treatment strategies. To make the ICU a more humane healing environment, these assessm...

journal_title：Critical care clinics

authors： Fraser GL,Riker RR

更新日期：2001-10-01 00:00:00

abstract：:This article describes the use of various scores and probabilities to clinically categorize patients in the adult intensive care unit. Some of the limitations of these severity measures are reviewed including variable definitions, timing of measurements, and whether models can be used for individual patients. Also, th...

journal_title：Critical care clinics

authors： Teres D,Lemeshow S

更新日期：1993-07-01 00:00:00

abstract：:Invasive fungal infections (IFI) and fungal sepsis in the intensive care unit are increasing and are associated with considerable morbidity and mortality. In this setting, IFI are predominantly caused by Candida species. Outcomes continue to be suboptimal; however, there are a few key clinician modifiable factors. PK-...

journal_title：Critical care clinics

authors： Lepak A,Andes D

更新日期：2011-01-01 00:00:00

abstract：:India is a vast democracy of nearly one billion people. Before the British rule ended in 1947, the life span of an Indian was a mere 21 years. Within a short span of 50 years, it increased to an impressive 63 years, largely due to public health measures initiated by the government. This created a pool of more than 300...

journal_title：Critical care clinics

authors： Udwadia FE,Guntupalli KK,Vidyasagar D

更新日期：1997-04-01 00:00:00

abstract：:The proportion of hospitalized patients with pulmonary embolism (PE) is increasing. Whether this represents more admissions with PE or more diagnoses made in hospitalized patients is uncertain. The proportion of hospitalized patients with deep venous thrombosis has decreased precipitously as a result of home treatment...

journal_title：Critical care clinics

authors： Stein PD,Matta F

更新日期：2011-10-01 00:00:00

abstract：:Vasodilators that affect the pulmonary vasculature are appealing adjuncts in many cardiopulmonary conditions that require mechanical ventilation such as ARDS, COPD, PPHN, and cardiothoracic surgery. The adverse systemic effects of parenteral PGE1 and parenteral prostacyclin limit their usefulness in critically ill pat...

journal_title：Critical care clinics

authors： Zimmerman JL,Hanania NA

更新日期：1998-10-01 00:00:00

abstract：:Vesicants (or blister agents) are cytotoxic alkylating compounds, which are chemical agents sometimes collectively known as mustard gas or simply as mustard. Other blister agents are nitrogen mustard; sulfur mustard; lewisite, a vesicant that contains arsenic; and phosgene oxime, a halogenated oxime that possesses dif...

journal_title：Critical care clinics

authors： McManus J,Huebner K

更新日期：2005-10-01 00:00:00

abstract：:Acute hypoxemic respiratory failure is a pulmonary capillary leak state that occurs in many different clinical settings. The resultant edema causes refractory hypoxemia due to intrapulmonary shunting and loss of lung compliance. Mechanical ventilation with PEEP and high concentrations of supplemental oxygen are freque...

journal_title：Critical care clinics

authors： Zucker AR

更新日期：1988-10-01 00:00:00

abstract：:Cardiovascular disease is the leading cause of death in the United States,and thus its clinical and economic implications are enormous. In an increasingly cost-conscious economic environment, it is important to understand not only the effectiveness of treatments and technologies but also their cost-effectiveness. The ...

journal_title：Critical care clinics

authors： Chen J,Rizzo JA

更新日期：2012-01-01 00:00:00

abstract：:Positive-pressure ventilation may improve gas exchange, decrease the work-cost of breathing, and rest respiratory muscles, but it also will alter cardiac output and may modify blood flow distribution. Ventilation may induce these hemodynamic changes by altering systemic venous return to the RV (RV preload), pulmonary ...

journal_title：Critical care clinics

authors： Pinsky MR

更新日期：1990-07-01 00:00:00

abstract：:The pathophysiology of the burn injury and treatment factors that influence burn depth are explained. Details of burn wound care, including indications for early excision, topical antimicrobials, and the most recent advances in skin substitutes, are described. Burn wound sepsis, the most common and serious complicatio...

journal_title：Critical care clinics

authors： Achauer BM,Martinez SE

更新日期：1985-03-01 00:00:00

abstract：:This article summarizes the biomechanical relationship of the spinal column to load stresses with respect to column failure, and the resulting associated central nervous system injury. In addition, it presents pertinent animal research, which has focused onto the development standardized animal spinal cord injury mode...

journal_title：Critical care clinics

authors： Bunegin L,Hung TK,Chang GL

更新日期：1987-07-01 00:00:00