Prediction of in-hospital mortality and morbidity using high-sensitivity C-reactive protein after burr hole craniostomy.

Abstract:

BACKGROUND:The purpose of this study was to assess whether preanesthetic laboratory values can predict in-hospital mortality and morbidity in patients who have undergone burr hole craniostomy due to chronic subdural hematoma. METHODS:From January 2007 to February 2016, the records of 502 consecutive patients who underwent burr hole craniotomy were analyzed. All cases of burr hole craniostomy were fitted with a drain, as required by our institutional protocol. RESULTS:Patients' demographic data and preoperative laboratory values were subjected to logistic regression analysis to predict in-hospital mortality and morbidity after burr hole craniostomy. Hemoglobin, prothrombin time, activated partial thromboplastin time, serum glucose, and high-sensitivity C-reactive protein (hsCRP) were found to be significantly associated with in-hospital mortality and morbidity by univariate regression analysis, but of these, only hsCRP (hazard ratio 1.210, 95 % confidence interval 1.089-1.345, P < 0.001) was found to significantly predict in-hospital mortality and morbidity by multivariate regression analysis. Areas under the curve for predicting in-hospital mortality and morbidity were 0.765 (95 % confidence interval 0.624-0.906, P = 0.002) and 0.646 (0.559-0.733, P = 0.001), respectively. CONCLUSIONS:Preoperative hsCRP was found to be an independent predictor of in-hospital mortality and morbidity after burr hole craniostomy due to chronic subdural hematoma.

journal_name

J Anesth

journal_title

Journal of anesthesia

authors

Choi JJ,Kim HS,Lee KC,Hur H,Jo YY

doi

10.1007/s00540-016-2259-1

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

956-960

issue

6

eissn

0913-8668

issn

1438-8359

pii

10.1007/s00540-016-2259-1

journal_volume

30

pub_type

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