Systemic administration of procaine suppresses the somato-sympathetic reflex discharges in anesthetized cats.

Abstract:

:Somato-sympathetic reflex discharges (SSRDs) which were induced from the lumbar sympathetic truck elicited by train pulse stimulation of femoral nerves in anesthetized cats were examined during and after intravenous infusion of 1 mg.kg(-1).min(-1) of procaine. The infusion demonstrated that amplitudes were suppressed with prolonged latencies and/or their tendencies in A- and C-reflex potentials of SSRDs. Heart rate and blood pressure decreased slightly, and the decreases correlated with time courses of suppressed SSRDs. These results suggest that the systemic procaine infusion may be a reliable method to alleviate somato-sympathetic reflexes under such conditions as extreme stimulation of somatic afferent nerves observed in surgical procedures.

journal_name

J Anesth

journal_title

Journal of anesthesia

authors

Xue FW,Ogawa S,Nakamura T,Kato J,Suzuki H

doi

10.1007/s0054020060461

subject

Has Abstract

pub_date

1992-10-01 00:00:00

pages

461-6

issue

4

eissn

0913-8668

issn

1438-8359

journal_volume

6

pub_type

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