Abstract:
:The antiarrhythmic effect of flecainide acetate (FCN), a newly developed class I antiarrhythmic drug, was evaluated on epinephrine (E)-halothane induced arrhythmias in dogs. The arrhythmogenic dose of E (ADE) under 1% of halothane was significantly increased from 0.71 +/- 0.08 to 1.08 +/- 0.11 and 1.84 +/- 0.23 micro g.kg(-1).min(-1) by the administration of 2 and 4 mg.kg(-1) of FCN, respectively. The arrhythmias induced by ADE in the absence of FCN were stopped by 1.78 +/- 0.29 mg.kg(-1) of FCN in bolus injections. These results suggest that FCN can be used for the treatment of arrhythmias that E contributes to under halothane anesthesia.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Iwatsuki N,Takahashi M,Satoh S,Tajima Tdoi
10.1007/s0054000040303subject
Has Abstractpub_date
1990-10-01 00:00:00pages
303-8issue
4eissn
0913-8668issn
1438-8359journal_volume
4pub_type
杂志文章abstract:PURPOSE:The incidence of postoperative pharyngolaryngeal complications after laryngeal mask airway (LMA) insertion can be as high as 50%. Over-inflation of the LMA cuff may be a causal factor. We conducted a single-centre parallel group randomised trial to determine whether maintaining LMA-ProSeal intra-cuff pressures ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-014-1811-0
更新日期:2014-10-01 00:00:00
abstract::A substantial proportion of patients with coronavirus disease 19 (COVID-19) develop severe respiratory failure. Although the exact pathophysiology of severe COVID-19 pneumonia remains unknown and the characteristics of these patients are heterogeneous, the acute respiratory failure often fulfills criteria for acute re...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02845-0
更新日期:2020-08-31 00:00:00
abstract:PURPOSE:Propofol and ketamine have become progressively popular in electroconvulsive therapy (ECT) anesthesia, although propofol shortened seizure duration and ketamine might cause cardiotoxicity, psychotic episodes, and delayed recovery. Ketofol is a combination of ketamine and propofol, and the current study was desi...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1378-6
更新日期:2012-08-01 00:00:00
abstract::We report a case of drug-induced myoclonus possibly related to palonosetron, a second-generation 5-hydroxytryptamine-3 receptor antagonist which was administered as a prophylaxis for postoperative nausea and vomiting in a 28-year-old female. The recurrent episodes of myoclonus jerk involving the head, neck and shoulde...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2228-8
更新日期:2016-12-01 00:00:00
abstract::The concentrations of extracellular glutamate (Glu), aspartate (Asp) and glycine (Gly) were measured by microdialysis method in the cortex and hippocampus before, during and after 15 min of total cerebral ischemia in dogs. The correlations between the concentrations of amino acids and the changes in EEG and evoked pot...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054030070334
更新日期:1993-07-01 00:00:00
abstract::The concentrations of placental transfer of halothane (H), enflurane (E), sevoflurane (S), and isoflurane (I) were measured in 46 patients during cesarean section. The mean inhalation times of H (0.5%), E (1%), S (0.8%), and I (0.6%) were 13 min 27 s, 13 min 49s, 13 min 20s, and 8 min 8s, respectively. The mean concen...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02479867
更新日期:1995-09-01 00:00:00
abstract:PURPOSE:Malignant hyperthermia (MH) results from disordered calcium (Ca(2+)) homeostasis in skeletal muscle during general anesthesia. Although Ca(2+) channel blockers may be given to treat the tachycardia and circulatory instability, coadministration of Ca(2+) channel blockers and dantrolene is contraindicated during ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1347-0
更新日期:2012-08-01 00:00:00
abstract:PURPOSE:Compared with open thoracotomy, minimally invasive esophagectomy (MIE) methods, such as transhiatal or thoracoscopic esophagectomy, likely have lower morbidity. However, the relationship between intraoperative fluid management and postoperative complications after MIE remains unclear. Thus, we investigated the ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02766-y
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Cardiac surgery and sternotomy are procedures accompanied by substantial postoperative pain which is challenging to treat. In general, intravenous (IV) opioids are used in the immediate postoperative phase, followed by oral opioids. Oral opioids are easier to use and generally less expensive. Our goal was th...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1770-x
更新日期:2014-08-01 00:00:00
abstract::With the aim to optimize surgical safety, the World Health Organization (WHO) introduced the Surgical Safety Checklist (SSCL) in 2008. The SSCL has been piloted in many countries worldwide and shown to improve both safety attitudes within surgical teams and patient outcomes. In the study reported here we investigated ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1737-y
更新日期:2014-06-01 00:00:00
abstract::Small children are physiologically subject to arterial oxygen desaturation. However, few reports have referred to the risk factors related to postanesthetic hypoxemia and the duration of hypoxemia. The purpose of this study was to clarify these two aspects. Eighty-five ASA physical status I infants and children were i...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054030070016
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:Volatile anesthetics affect the cardiovascular and immune systems. Toward a better understanding of the molecular mechanisms behind the modulation exerted by these agents, we focused on the effects of halothane and isoflurane on the activation of p38 mitogen-activated protein kinase (MAPK), which plays a critic...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-004-0237-5
更新日期:2004-01-01 00:00:00
abstract::The anesthesia information management system (AIMS) will be part of the future of healthcare. An electronic medical records system or AIMS will provide clear and concise information and have the potential to integrate information across the entire hospital system, improve quality of care, reduce errors, decrease risks...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-008-0643-1
更新日期:2008-01-01 00:00:00
abstract::Anesthetic management of anterior mediastinal masses (AMM) is challenging. We describe the successful anesthetic management of two patients with AMM in which dexmedetomidine was used at supra-sedative doses. Our first case was a 41-year-old man who presented with a 10 x 9 x 11 cm AMM, a pericardial effusion, compressi...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-010-0946-x
更新日期:2010-08-01 00:00:00
abstract::Isolated adrenocorticotropic hormone (ACTH) deficiency is an extremely rare disease in which ACTH-producing cells of the pituitary gland are selectively damaged. The resulting decline in ACTH production and secretion results in chronic secondary adrenocortical insufficiency. The patient in this case did not present wi...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1118-3
更新日期:2011-06-01 00:00:00
abstract::A large amount of pharmacological and clinical evidence supports the abuse potential of propofol. Although previous case reports have indicated that recreational use of propofol is primarily by medical professionals, its spread among the general public has recently been highlighted. This is the first case report to sh...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1275-4
更新日期:2012-04-01 00:00:00
abstract:PURPOSE:In a previous study using the tail-flick test, we found that intracerebroventricular administration of D-serine, an endogenous co-agonist at the glycine sites of N-methyl-D-aspartate (NMDA) receptors, elicited an antinociceptive effect on thermal nociception. The purpose of the present study was to evaluate the...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1708-3
更新日期:2014-04-01 00:00:00
abstract::Takotsubo cardiomyopathy is an acute syndrome involving apical ballooning and consequent dysfunction of the left ventricle. Most cases of left ventricular dysfunction resolve within 1 month. We present the case of a 40-year-old woman who developed severe heart failure caused by takotsubo cardiomyopathy with severe lef...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1677-6
更新日期:2014-02-01 00:00:00
abstract::Holmium laser enucleation of prostate (HoLEP) is being performed with increasing frequency as a minimally invasive alternative to transurethral resection of the prostate (TURP) for the surgical management of benign prostatic hyperplasia (BPH). HoLEP offers the advantage of use of normal saline for irrigation, instead ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2256-4
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:We aimed to compare retrospectively the rates of renal morbidity and mortality in surgical patients receiving 6% HES 130/0.4 to those receiving albumin. METHODS:From a Japanese nationwide medical database between 2014 and 2016, we identified adults who received HES 130/0.4 (HES group) or albumin (albumin group...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02838-z
更新日期:2020-12-01 00:00:00
abstract::Within continuously controlled limits of cuff pressure, an endotracheal tube cuff made of polyurethane (PU) prevents secretion inflow better than a conventional polyvinylchloride cuff. However, the temperature difference between ventilator gas and the air inside a PU cuff produces condensation droplets that accumulate...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1849-z
更新日期:2014-12-01 00:00:00
abstract::Thirty six patients were received epidural anesthesia with or without buprenorphine (BPN) during upper abdominal surgery. They were divided into three groups of 12 patients as follows; G-I received 20 ml of 1% lidocaine epidurally, G-II received 20 ml of 1% lidocaine epidurally and 0.6 mg BPN intravenously, G-III rece...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054000040242
更新日期:1990-07-01 00:00:00
abstract::Cardiac surgery is associated with a high incidence of cardiovascular and other complications during the perioperative period that translate into increased mortality and prolonged hospital stays. Safe comprehensive perioperative management is required to eliminate these adverse events. Dexmedetomidine is a selective α...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-014-1857-z
更新日期:2015-02-01 00:00:00
abstract::Recently, ultrasound-guided caudal anesthesia has been performed for postoperative pain management after lumbar spine surgery. Although it is well known that intravascular injection often occurs in the caudal part of the spine, and that this cannot be detected at the time of injection under ultrasound screening, the r...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1840-8
更新日期:2014-12-01 00:00:00
abstract::To determine whether there is any systemic relationship between the distance from the skin to the epidural space and physical constitution, the distance from the skin to the epidural space was measured in 1007 epidural punctures. The distance from the skin to the epidural space in male was greater than that in female ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054080020198
更新日期:1988-09-01 00:00:00
abstract::Neuropathic pain has a substantial effect on quality of life (QOL). The Japanese Society of Pain Clinicians (JSPC) has developed clinical guidelines of pharmacotherapy for neuropathic pain. These guidelines offer clarity on recommendations based on both the most recent scientific evidence and expert opinions. Understa...
journal_title:Journal of anesthesia
pub_type: 杂志文章,实务指引
doi:10.1007/s00540-018-2501-0
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:Hypoxia promotes the progression of lung cancer cells. Unfortunately, anesthetic technique might aggravate hypoxia of lung cancer cells. Sevoflurane is a commonly used anesthetic. Its effect on hypoxia-induced aggressiveness of lung cancer cells remains unknown. The aim of the study is to investigate the effect...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-015-2035-7
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:Intrathecal morphine provides superior pain control for patients undergoing cesarean delivery when compared to intravenous opioid patient-controlled analgesia. However, no study has assessed the overall cost associated with each modality as a primary outcome. The aim of this study is to determine the overall co...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2263-5
更新日期:2017-02-01 00:00:00
abstract::The impact of postoperative atrial fibrillation (PAF) on patient outcomes has prompted intense investigation into the optimal methods for prevention and treatment of this complication. In the prevention of PAF, β-blockers and amiodarone are particularly effective and are recommended by guidelines. However, their use r...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-012-1330-9
更新日期:2012-06-01 00:00:00
abstract::Fifteen surgical patients received an epidural injection of 12 ml of 1.5% lidocaine through a catheter placed at C7-T1, followed by further injection as required. An intravenous bolus of 0.5 mg of atropine sulfate was administered simultaneously with the initial epidural injection. The high-(HFC: 0.15-0.4 Hz) and low-...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02482031
更新日期:1995-03-01 00:00:00