Abstract:
:The study aimed to investigate local thermally induced microvascular reactivity in patients with type 1 (T1DM) or type 2 diabetes mellitus (T2DM) and polyneuropathy and to compare it with healthy controls. A hundred and fourteen subjects were investigated divided into 3 groups: 1st group -20 patients with T1DM; 2nd group -50 patients with T2DM; 3rd group -44 healthy controls. The skin perfusions of the first tiptoe were monitored by laser Doppler flowmetry during thermal test. The initial (PUi) and basal perfusions at 32°C (PUb) tended to be higher in the DM groups and the PUb of T1DM group was higher compared with the healthy subjects. The perfusion responses to heating were attenuated in the patients compared with the controls. The calculated vasodilator heat-induced indices were significantly lower and the vasoconstrictor indices during relative cooling in the recovery period were significantly higher in DM patients related to the healthy subjects. The reduced cutaneous microvascular responses to local thermal stimulation in the plantar sides of the toes of both T1DM and T2DM patients with polyneuropathy were similar to those found by previous studies in other investigated sites of glabrous and nonglabrous skin of patients with DM.
journal_name
Clin Hemorheol Microcircjournal_title
Clinical hemorheology and microcirculationauthors
Stoyneva Z,Velcheva I,Antonova N,Titianova Edoi
10.3233/CH-15107subject
Has Abstractpub_date
2017-01-01 00:00:00pages
67-75issue
1eissn
1386-0291issn
1875-8622pii
CH15107journal_volume
65pub_type
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journal_title:Clinical hemorheology and microcirculation
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journal_title:Clinical hemorheology and microcirculation
pub_type: 杂志文章
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更新日期:2008-01-01 00:00:00
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更新日期:2020-01-01 00:00:00
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journal_title:Clinical hemorheology and microcirculation
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更新日期:2000-01-01 00:00:00
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更新日期:2019-01-01 00:00:00
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journal_title:Clinical hemorheology and microcirculation
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doi:
更新日期:1999-01-01 00:00:00
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journal_title:Clinical hemorheology and microcirculation
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
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更新日期:2020-10-13 00:00:00
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doi:
更新日期:2006-01-01 00:00:00
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journal_title:Clinical hemorheology and microcirculation
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journal_title:Clinical hemorheology and microcirculation
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更新日期:1999-01-01 00:00:00
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更新日期:2010-01-01 00:00:00
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更新日期:2018-01-01 00:00:00
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journal_title:Clinical hemorheology and microcirculation
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更新日期:2005-01-01 00:00:00
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