Abstract:
:In a randomized study 87 patients received perioperative antibiotic prophylaxis with 2 x 2 g ceftriaxone (Rocephin) at the beginning of the operation and in the following morning. Seventy-two patients received no antibiotic prophylaxis. In patients receiving the prophylaxis, a lower incidence of infections was observed postoperatively in addition to a reduction in wound-healing disorders. Respiratory tract infections were more successfully prevented than urinary tract infections. The number of pathogenic bacteria detected in the group on receiving prophylaxis decreased. The positive effect of the perioperative administration of antibiotics was more evident in protracted operations, such as brain surgery, than in operations involving the spinal cord.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Winkler D,Rehn H,Freckmann N,Nowak G,Herrmann HDdoi
10.1159/000238686subject
Has Abstractpub_date
1989-01-01 00:00:00pages
304-12issue
4eissn
0009-3157issn
1421-9794journal_volume
35pub_type
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