Abstract:
AIM:To evaluate whether the congested area that develops in associating liver partition with portal vein ligation for staged hepatectomy (ALPPS) contributes to rapid future liver remnant (FLR) hypertrophy. PATIENTS AND METHODS:Eight patients undergoing liver partition and right portal vein (RPV) ligation within the FLR in the first operation of ALPPS were compared with eight patients undergoing RPV embolization in the FLR as the first operation of classical two-stage (CTS) hepatectomy. RESULTS:Extrapolated kinetic growth of the FLR in ALPPS was 32.7±18.7 ml/day, 7.8-times that in CTS (4.2±2.0 ml/day, p=0.001). Extrapolated kinetic reduction in volume of the ventral aspect of the right paramedian sector, which became congested after the first procedure in ALPPS, was 19.8±11.6 ml/day, 11-times that in CTS (1.8±1.3 ml/day, p=0.001). CONCLUSION:Production of a congested area within the deportalized liver may contribute importantly to rapid FLR hypertrophy during ALPPS.
journal_name
Anticancer Resjournal_title
Anticancer researchauthors
Kawaguchi D,Hiroshima Y,Matsuo K,Endo I,Koda K,Tanaka Kdoi
10.21873/anticanres.11028subject
Has Abstractpub_date
2016-09-01 00:00:00pages
4731-8issue
9eissn
0250-7005issn
1791-7530pii
36/9/4731journal_volume
36pub_type
杂志文章abstract:BACKGROUND/AIM:The single nucleotide polymorphism -31C/G identified in the survivin gene promoter seems to be associated with over-expression of survivin, an anti-apoptotic protein. In gliomas, increased survivin expression correlated with decreased survival. The aim of the study was to investigate whether survivin gen...
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