Adherence to Antihypertensive Treatment and the Blood Pressure-Lowering Effects of Renal Denervation in the Renal Denervation for Hypertension (DENERHTN) Trial.

abstract：BACKGROUND:There is an inverse relationship between HDL cholesterol and coronary heart disease. Experimental studies have indicated that HDL cholesterol may exert an antiatherogenic effect by inducing regression of atherosclerotic plaques and by turning lipid-rich plaques into more fibrotic lesions. In this prospective...

journal_title：Circulation

authors： Johnsen SH,Mathiesen EB,Fosse E,Joakimsen O,Stensland-Bugge E,Njølstad I,Arnesen E

更新日期：2005-07-26 00:00:00

abstract：BACKGROUND:The strategy for treating patients with severe asymptomatic carotid artery stenosis and cardiac disease remains unresolved. Staged or combined carotid endarterectomy in these patients offers the potential benefit of decreased neurological morbidity during and after cardiac surgery; however, in high-risk pati...

journal_title：Circulation

authors： Van der Heyden J,Suttorp MJ,Bal ET,Ernst JM,Ackerstaff RG,Schaap J,Kelder JC,Schepens M,Plokker HW

更新日期：2007-10-30 00:00:00

abstract：BACKGROUND:In the Basel Antiarrhythmic Study of Infarct Survival trial, low-dose amiodarone improved 1-year survival in patients with asymptomatic complex ventricular arrhythmias persisting 2 weeks after myocardial infarction. To assess whether this beneficial effect persisted despite discontinuation of amiodarone afte...

journal_title：Circulation

authors： Pfisterer ME,Kiowski W,Brunner H,Burckhardt D,Burkart F

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Cardiomyocyte hypertrophy is a critical precursor to the development of heart failure. Methods to phenotype cellular hypertrophy noninvasively are limited. The goal was to validate a cardiac magnetic resonance-based approach for the combined assessment of extracellular matrix expansion and cardiomyocyte hype...

journal_title：Circulation

authors： Coelho-Filho OR,Shah RV,Mitchell R,Neilan TG,Moreno H Jr,Simonson B,Kwong R,Rosenzweig A,Das S,Jerosch-Herold M

更新日期：2013-09-10 00:00:00

abstract：BACKGROUND:Various measures of arterial stiffness and wave reflection have been proposed as cardiovascular risk markers. Prior studies have not assessed relations of a comprehensive panel of stiffness measures to prognosis in the community. METHODS AND RESULTS:We used proportional hazards models to analyze first-onset...

journal_title：Circulation

authors： Mitchell GF,Hwang SJ,Vasan RS,Larson MG,Pencina MJ,Hamburg NM,Vita JA,Levy D,Benjamin EJ

更新日期：2010-02-02 00:00:00

abstract：BACKGROUND:Increased carotid intimal-medial thickness (IMT) and coronary artery calcification (CAC) are used as 2 markers of early atherosclerosis. Our objectives were to assess whether increased IMT and CAC are related and to determine the relationship between cardiovascular risk factors and carotid IMT in young adult...

journal_title：Circulation

authors： Davis PH,Dawson JD,Mahoney LT,Lauer RM

更新日期：1999-08-24 00:00:00

abstract：BACKGROUND:Cyclosporin A is reported to impair endothelium-mediated vasorelaxation and induce endothelin release in some noncoronary vascular beds. We wished to determine whether acute cyclosporine administration induces endothelial dysfunction in coronary conductance or resistance arteries. METHODS AND RESULTS:We exa...

journal_title：Circulation

authors： Sudhir K,MacGregor JS,DeMarco T,De Groot CJ,Taylor RN,Chou TM,Yock PG,Chatterjee K

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Vascular inflammation and subsequent matrix degradation play an important role in the development of atherosclerosis. We previously reported that adiponectin, an adipose-specific plasma protein, accumulated to the injured artery and attenuated vascular inflammatory response. Clinically, high plasma adiponect...

journal_title：Circulation

authors： Kumada M,Kihara S,Ouchi N,Kobayashi H,Okamoto Y,Ohashi K,Maeda K,Nagaretani H,Kishida K,Maeda N,Nagasawa A,Funahashi T,Matsuzawa Y

更新日期：2004-05-04 00:00:00

abstract：BACKGROUND:A line of block in the right atrium (RA) between the venae cavae is necessary to obtain classic atrial flutter (AFL). We tested the hypothesis that the location of that line of block would determine whether the AFL reentrant circuit would be due to single-loop reentry or figure-of-8 reentry. METHODS AND RES...

journal_title：Circulation

authors： Tomita Y,Matsuo K,Sahadevan J,Khrestian CM,Waldo AL

更新日期：2001-02-20 00:00:00

abstract：BACKGROUND:A low ankle-arm index (AAI) is a strong predictor of mortality and cardiovascular events. A high AAI also appears to be associated with higher mortality risk in select populations. However, mortality and cardiovascular risk across the AAI spectrum have not been described in a more broadly defined population....

journal_title：Circulation

authors： O'Hare AM,Katz R,Shlipak MG,Cushman M,Newman AB

更新日期：2006-01-24 00:00:00

abstract：BACKGROUND:Molecular targeted chemotherapies have been shown to significantly improve the outcomes of patients who have cancer, but they often cause cardiovascular side effects that limit their use and impair patients' quality of life. Cardiac dysfunction induced by these therapies, especially trastuzumab, shows a dist...

journal_title：Circulation

authors： Kitani T,Ong SG,Lam CK,Rhee JW,Zhang JZ,Oikonomopoulos A,Ma N,Tian L,Lee J,Telli ML,Witteles RM,Sharma A,Sayed N,Wu JC

更新日期：2019-05-21 00:00:00

abstract：BACKGROUND:Pulmonary hypertension (PH) is a life-threatening disorder characterized by increased pulmonary artery pressure, remodeling of the pulmonary vasculature, and right ventricular failure. Loss of endothelium-derived nitric oxide (NO) and prostacyclin contributes to PH pathogenesis, and current therapies are tar...

journal_title：Circulation

authors： Bubb KJ,Trinder SL,Baliga RS,Patel J,Clapp LH,MacAllister RJ,Hobbs AJ

更新日期：2014-08-05 00:00:00

abstract：BACKGROUND:Friedreich's ataxia (FA), the most common inherited ataxia, is associated frequently with cardiac hypertrophy, and death is often cardiac related. Recently, the disease has been associated with a mutation that consists of an unstable expansion of GAA repeats in the first intron of the gene encoding frataxin ...

journal_title：Circulation

authors： Isnard R,Kalotka H,Dürr A,Cossée M,Schmitt M,Pousset F,Thomas D,Brice A,Koenig M,Komajda M

更新日期：1997-05-06 00:00:00

abstract：:The effect of cycle length on atrial vulnerability was studied in 14 patients manifesting reproducible repetitive atrial firing during atrial extra-stimulus (A2) testing. Repetitive atrial firing was defined as the occurrence of two or more premature atrial responses with return cycle (A2-A3) of 250 msec or less and s...

journal_title：Circulation

authors： Wyndham CR,Amat-y-Leon F,Wu D,Denes P,Dhingra R,Simpson R,Rosen KM

更新日期：1977-02-01 00:00:00

abstract：:The sensitivity of the baroreceptor reflex in nine patients with borderline hypertension (mean age 19.1 plus or minus 0.2 years) was compared to that in six normal subjects of comparable age (mean 18.8 plus or minus 0.3 years) and that in 14 patients with established hypertension (mean age 48.3 plus or minus 3.1 years...

journal_title：Circulation

authors： Takeshita A,Tanaka S,Kuroiwa A,Nakamura M

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:Mechanisms favoring the occurrence of paroxysmal atrial fibrillation (PAF) are complex and poorly defined. This study was designed to analyze dynamic changes in autonomic tone preceding the onset of PAF in a large group of patients. METHODS AND RESULTS:Holter tapes from 77 unselected consecutive patients (6...

journal_title：Circulation

authors： Bettoni M,Zimmermann M

更新日期：2002-06-11 00:00:00

abstract：BACKGROUND:Although surgery is indicated in patients with mitral regurgitation (MR) when left ventricular (LV) end-systolic (LVES) dimension is >40 mm, LV ejection fraction may decrease after mitral valve surgery. We hypothesize that significant LV remodeling before surgery is not reflected by standard echocardiographi...

journal_title：Circulation

authors： Schiros CG,Dell'Italia LJ,Gladden JD,Clark D 3rd,Aban I,Gupta H,Lloyd SG,McGiffin DC,Perry G,Denney TS Jr,Ahmed MI

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:PCTP (phosphatidylcholine transfer protein) regulates the intermembrane transfer of phosphatidylcholine. Higher platelet PCTP expression is associated with increased platelet responses on activation of protease-activated receptor 4 thrombin receptors noted in black subjects compared with white subjects. Litt...

journal_title：Circulation

authors： Mao G,Songdej N,Voora D,Goldfinger LE,Del Carpio-Cano FE,Myers RA,Rao AK

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Antiplatelet agents presently used in the secondary prevention of cardiovascular disease fail to prevent the majority of cases of recurrent stroke and systemic embolization. An evaluation of the efficacy of new agents is hampered by a lack of in vivo models in humans. Asymptomatic cerebral embolic signals (E...

journal_title：Circulation

authors： Molloy J,Martin JF,Baskerville PA,Fraser SC,Markus HS

更新日期：1998-10-06 00:00:00

abstract：:A longitudinal study was made of 62 patients with dextro-transposition of the great arteries. The patients were managed with balloon atrial septostomy (BAS), palliative surgery if any operation was needed in the first year of life, and Mustard intra-atrial baffle repair after one year of age. Of the 47 patients with i...

journal_title：Circulation

authors： Gutgesell HP,McNamara DG

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:Despite a recent American Heart Association (AHA) consensus statement emphasizing the importance of resistant hypertension, the incidence and prognosis of this condition are largely unknown. METHODS AND RESULTS:This retrospective cohort study in 2 integrated health plans included patients with incident hype...

journal_title：Circulation

authors： Daugherty SL,Powers JD,Magid DJ,Tavel HM,Masoudi FA,Margolis KL,O'Connor PJ,Selby JV,Ho PM

更新日期：2012-04-03 00:00:00

abstract：:The electrophysiologic effects of intravenously administered disopyramide (2 mg/kg) on three parameters of sinus node function were examined in 16 symptomatic patients with sinus node dysfunction. Based on their ECG data before study, patients were subdivided into group A (n = 8), those with sinus pauses and/or sinoat...

journal_title：Circulation

authors： LaBarre A,Strauss HC,Scheinman MM,Evans GT,Bashore T,Tiedeman JS,Wallace AG

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:The isthmus between the inferior vena cava and the tricuspid annulus has been shown to be involved in the reentry circuit of common atrial flutter. The effects of radio-frequency catheter ablation of this isthmus were examined in the canine model of atrial flutter due to reentry around the tricuspid annulus....

journal_title：Circulation

authors： Tabuchi T,Okumura K,Matsunaga T,Tsunoda R,Jougasaki M,Yasue H

更新日期：1995-09-01 00:00:00

abstract：:Left ventricular ejection fraction (LVEF) was measured by radionuclide angiography at rest and during supine bicycle exercise before and 3 months after coronary artery bypass graft surgery (CABG) in 20 patients with chronic stable angina. The right anterior oblique gated first-pass technique was used to assess LVEF re...

journal_title：Circulation

authors： Lim YL,Kalff V,Kelly MJ,Mason PJ,Currie PJ,Harper RW,Anderson ST,Federman J,Stirling GR,Pitt A

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:The cytoskeleton plays an important role in maintaining cell structure and integrity. Defects in cytoskeletal proteins can cripple cell strength and may cause cardiomyopathy. We analyzed heart tissues from subjects with dilated cardiomyopathy for abnormalities in the cardiac cytoskeleton. Metavinculin, a car...

journal_title：Circulation

authors： Maeda M,Holder E,Lowes B,Valent S,Bies RD

更新日期：1997-01-07 00:00:00

abstract：BACKGROUND:Treatment of aortocaval fistulae (ACFs) by open surgery is known to be a high-risk procedure. In this experimental study, we developed a percutaneous model of ACF to test a new nonsurgical method of treatment of ACF using endovascular stent grafts. METHODS AND RESULTS:An ACF was created percutaneously in ei...

journal_title：Circulation

authors： Boudghène F,Sapoval M,Bonneau M,Bigot JM

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:The results of angiographic studies have suggested that calcium channel-blocking agents may prevent new coronary lesion formation, the progression of minimal lesions, or both. METHODS AND RESULTS:The Prospective Randomized Evaluation of the Vascular Effects of Norvasc Trial (PREVENT) was a multicenter, rand...

journal_title：Circulation

authors： Pitt B,Byington RP,Furberg CD,Hunninghake DB,Mancini GB,Miller ME,Riley W

更新日期：2000-09-26 00:00:00

abstract：:The initial myocardial uptake of thallium-201 depends on myocardial blood flow distribution. The phenomenon of delayed thallium redistribution after transiently or chronically altered myocardial perfusion has been described. The net myocardial accumulation of thallium-201 after injection depends upon the net balance b...

journal_title：Circulation

authors： Grunwald AM,Watson DD,Holzgrefe HH Jr,Irving JF,Beller GA

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Selection of treatment in vasovagal syndrome should be guided by the mechanism of symptoms. This study determined whether a simple drug test may assess one mechanism. METHODS AND RESULTS:To identify patients at risk of severe cardioinhibitory response of vagal origin, we infused 20 mg ATP into 316 patients ...

journal_title：Circulation

authors： Flammang D,Church T,Waynberger M,Chassing A,Antiel M

更新日期：1997-08-19 00:00:00

abstract：BACKGROUND:Although early trials indicate the treatment of restenosis with radiation therapy is safe and effective, the long-term impact of this new technology has been questioned. The possibility of late untoward consequences, such as aneurysm formation, perforation, and accelerated vascular disease, is of significant...

journal_title：Circulation

authors： Teirstein PS,Massullo V,Jani S,Russo RJ,Cloutier DA,Schatz RA,Guarneri EM,Steuterman S,Sirkin K,Norman S,Tripuraneni P

更新日期：1999-01-19 00:00:00