Linear ablation of the isthmus between the inferior vena cava and tricuspid annulus for the treatment of atrial flutter. A study in the canine atrial flutter model.

abstract：:Myocardial lactate production indicates anaerobic metabolism resulting from hypoxia or anoxia. Clinically, myocardial lactate extraction of less than 10% has also been used as an indicator of ischemia. Sixteen healthy young male volunteers underwent coronary sinus and aterial catheterization. A coronary sinus pacing c...

journal_title：Circulation

authors： Gertz EW,Wisneski JA,Neese R,Houser A,Korte R,Bristow JD

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Several noninvasive methods are available to investigate the severity of extracoronary atherosclerotic disease. No population-based study has yet examined whether differences exist between these measures with regard to their predictive value for myocardial infarction (MI) or whether a given measure of athero...

journal_title：Circulation

authors： van der Meer IM,Bots ML,Hofman A,del Sol AI,van der Kuip DA,Witteman JC

更新日期：2004-03-09 00:00:00

abstract：BACKGROUND:The therapeutic effects of nonspecific beta-blockers are limited by vasoconstriction, thus justifying the interest in molecules with ancillary vasodilating properties. Nebivolol is a selective beta1-adrenoreceptor antagonist that releases nitric oxide (NO) through incompletely characterized mechanisms. We id...

journal_title：Circulation

authors： Dessy C,Saliez J,Ghisdal P,Daneau G,Lobysheva II,Frérart F,Belge C,Jnaoui K,Noirhomme P,Feron O,Balligand JL

更新日期：2005-08-23 00:00:00

abstract：:The linearity and sensitivity of the end-systolic pressure-volume (P-Ves) relation to the inotropic state of the left ventricle were investigated in 11 patients with coronary heart disease and one patient with congestive cardiomyopathy. To minimize autonomic reflex responses, propranolol, 0.15 mg/kg, and atropine, 1 m...

journal_title：Circulation

authors： Mehmel HC,Stockins B,Ruffmann K,von Olshausen K,Schuler G,Kübler W

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:An association of chronic Chlamydia pneumoniae infection to coronary heart disease has been suggested recently. In a recent study, we demonstrated circulating immune complexes containing chlamydial genus-specific lipopolysaccharide in patients with coronary heart disease. The objective of the present study w...

journal_title：Circulation

authors： Linnanmäki E,Leinonen M,Mattila K,Nieminen MS,Valtonen V,Saikku P

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Intentional weight loss is associated with lower risk of heart failure (HF) and atherosclerotic cardiovascular disease among patients with type 2 diabetes. However, the contribution of baseline measures and longitudinal changes in fat mass (FM), lean mass (LM), and waist circumference (WC) to the risk of HF ...

journal_title：Circulation

authors： Patel KV,Bahnson JL,Gaussoin SA,Johnson KC,Pi-Sunyer X,White U,Olson KL,Bertoni AG,Kitzman DW,Berry JD,Pandey A,Look AHEAD Research Group.

更新日期：2020-12-22 00:00:00

abstract：BACKGROUND:Prosthetic valve thrombosis during pregnancy is life-threatening for mother and fetus, and the treatment of this complication is unclear. Cardiac surgery in pregnancy is associated with very high maternal and fetal mortality and morbidity. Thrombolytic therapy has rarely been used in these patients. The aim ...

journal_title：Circulation

authors： Özkan M,Çakal B,Karakoyun S,Gürsoy OM,Çevik C,Kalçık M,Oğuz AE,Gündüz S,Astarcioglu MA,Aykan AÇ,Bayram Z,Biteker M,Kaynak E,Kahveci G,Duran NE,Yıldız M

更新日期：2013-07-30 00:00:00

abstract：BACKGROUND:Treatment of aortocaval fistulae (ACFs) by open surgery is known to be a high-risk procedure. In this experimental study, we developed a percutaneous model of ACF to test a new nonsurgical method of treatment of ACF using endovascular stent grafts. METHODS AND RESULTS:An ACF was created percutaneously in ei...

journal_title：Circulation

authors： Boudghène F,Sapoval M,Bonneau M,Bigot JM

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:Human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) are a promising source of cells for regenerating myocardium. However, several issues, especially the large-scale preparation of hiPS-CMs and elimination of undifferentiated iPS cells, must be resolved before hiPS cells can be used clinical...

journal_title：Circulation

authors： Kawamura M,Miyagawa S,Miki K,Saito A,Fukushima S,Higuchi T,Kawamura T,Kuratani T,Daimon T,Shimizu T,Okano T,Sawa Y

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Selection of treatment in vasovagal syndrome should be guided by the mechanism of symptoms. This study determined whether a simple drug test may assess one mechanism. METHODS AND RESULTS:To identify patients at risk of severe cardioinhibitory response of vagal origin, we infused 20 mg ATP into 316 patients ...

journal_title：Circulation

authors： Flammang D,Church T,Waynberger M,Chassing A,Antiel M

更新日期：1997-08-19 00:00:00

abstract：BACKGROUND:Recent studies have shown that improved myocardial salvage after heat-shock pretreatment correlates with the amount of induced cardiac heat-shock protein (HSP)72. However, heat shock also induces myocardial catalase activity, potentially reducing free radical-mediated ischemic injury. The aim of the present ...

journal_title：Circulation

authors： Auyeung Y,Sievers RE,Weng D,Barbosa V,Wolfe CL

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Endothelium-derived nitric oxide is an important modulator of resting vascular tone in animals and humans. However, the contribution of nitric oxide to exercise-induced vasodilation is unknown. METHODS AND RESULTS:The effect of NG-monomethyl-L-arginine (L-NMMA), an inhibitor of nitric oxide synthesis, on ex...

journal_title：Circulation

authors： Gilligan DM,Panza JA,Kilcoyne CM,Waclawiw MA,Casino PR,Quyyumi AA

更新日期：1994-12-01 00:00:00

abstract：:One thousand four Medtronic Hall valves (601 mitral, 398 aortic, and five tricuspid) were implanted in 847 patients between December 1979 and June 1987. Total experience at the end of June 1987 was 2,640 patient-years of follow-up. Prothrombin time ratios were reviewed for all patients (16,866 observations), and these...

journal_title：Circulation

authors： Butchart EG,Lewis PA,Grunkemeier GL,Kulatilake N,Breckenridge IM

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:Since the clinical introduction of dynamic cardiomyoplasty, a discrepancy has been observed between unchanged measurements of cardiac function and improved clinical outcome. METHODS AND RESULTS:We performed a beat-to-beat analysis of cardiac performance at rest in nine cardiomyoplasty patients 6 to 24 month...

journal_title：Circulation

authors： Schreuder JJ,van der Veen FH,van der Velde ET,Delahaye F,Alfieri O,Jegaden O,Lorusso R,Jansen JR,van Ommen V,Finet G

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:We recently reported that sodium channel block can produce opposite effects on action potential duration (APD) and refractoriness in epicardial versus endocardial tissues of the canine ventricle. In addition, strong sodium channel current inhibition was found to cause loss of the action potential dome in epi...

journal_title：Circulation

authors： Krishnan SC,Antzelevitch C

更新日期：1993-02-01 00:00:00

abstract：:Asymptomatic ischemia after myocardial infarction is a common clinical problem. As much as 50% of the postinfarction patient population who have ischemia on exercise testing may have no symptoms at all. In these patients, ischemia detected by either exercise testing or ambulatory electrocardiographic monitoring, with ...

journal_title：Circulation

authors： Yeung AC,Barry J,Selwyn AP

更新日期：1990-09-01 00:00:00

abstract：:Iron catalysis is involved in oxygen-derived free radical generation and subsequent lipid peroxidation, which have been reported to occur during cardiopulmonary bypass in humans. We assessed the effects of the iron chelator deferoxamine on the susceptibility of circulating low density lipoproteins (LDLs) to induced pe...

journal_title：Circulation

authors： Menasché P,Antebi H,Alcindor LG,Teiger E,Perez G,Giudicelli Y,Nordmann R,Piwnica A

更新日期：1990-11-01 00:00:00

abstract：:The purpose of this investigation was to determine whether blood vessels could develop de novo between an extracardiac artery and a collateral-dependent zone of the heart and to quantify the nutritive blood flow afforded by the new vessels. We also adapted the preparation so that angiogenically active agents could be ...

journal_title：Circulation

authors： Unger EF,Sheffield CD,Epstein SE

更新日期：1990-10-01 00:00:00

abstract：:The relation between left atrial size and atrial fibrillation was examined in 37 patients who had left ventriculomyotomy and myectomy at the National Heart and Lung Institute. Atrial fibrillation was present in 11 of 27 (41%) patients with an echocardiographically measured left atrial dimension greater than 45 mm. No ...

journal_title：Circulation

authors： Watson DC,Henry WL,Epstein SE,Morrow AG

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:A paucity of literature is available on the effects of age and coronary artery bypass grafting (CABG) on the outcomes of patients undergoing mitral valve (MV) repair versus replacement. METHODS AND RESULTS:A matched study was performed using prospectively collected data from the Emory cardiovascular databas...

journal_title：Circulation

authors： Thourani VH,Weintraub WS,Guyton RA,Jones EL,Williams WH,Elkabbani S,Craver JM

更新日期：2003-07-22 00:00:00

abstract：BACKGROUND:Chlamydia pneumoniae stimulates chronic inflammation in vascular cells. Hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) may have an ameliorating effect. We investigated possible mechanisms. METHODS AND RESULTS:We infected human macrophages that in coculture spread infection to vascular smoot...

journal_title：Circulation

authors： Dechend R,Gieffers J,Dietz R,Joerres A,Rupp J,Luft FC,Maass M

更新日期：2003-07-22 00:00:00

abstract：BACKGROUND:In an open-label blinded study, we compared intracoronary and transendocardial CD34(+) cell transplantation in patients with nonischemic dilated cardiomyopathy. METHODS AND RESULTS:Of the 40 patients with dilated cardiomyopathy, 20 were randomized to receive intracoronary injection and 20 received transendo...

journal_title：Circulation

authors： Vrtovec B,Poglajen G,Lezaic L,Sever M,Socan A,Domanovic D,Cernelc P,Torre-Amione G,Haddad F,Wu JC

更新日期：2013-09-10 00:00:00

abstract：BACKGROUND:Vasodilator drugs have variable effects on veins and arteries. However, direct measurements of their effects on the splanchnic veins, perhaps the most important volume reservoir, have not been reported. We assessed the effect of acute heart failure and the subsequent administration of hydralazine, enalaprila...

journal_title：Circulation

authors： Wang SY,Manyari DE,Scott-Douglas N,Smiseth OA,Smith ER,Tyberg JV

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:Continuous-flow rotary pumps with axial design are increasingly used for left ventricular assist support. The efficacy of this design compared with pulsatile, volume displacement pumps, with respect to characteristics of left ventricular unloading, and exercise performance remains largely unstudied. METHODS...

journal_title：Circulation

authors： Haft J,Armstrong W,Dyke DB,Aaronson KD,Koelling TM,Farrar DJ,Pagani FD

更新日期：2007-09-11 00:00:00

abstract：:Thirty-one published reports (366 patients) and 48 consecutive patients treated for postinfarction ventricular septal defect at four institutions in northern California were reviewed. Overall hospital mortality was 43% in the reviewed group and was not affected by age, concomitant myocardial revascularization, date of...

journal_title：Circulation

authors： Hill JD,Stiles QR

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:In this study we tested the hypothesis that atrial fibrillation (AF) causes electrophysiological changes of the atrial myocardium which might explain the progressive nature of the arrhythmia. METHODS AND RESULTS:Twelve goats were chronically instrumented with multiple electrodes sutured to the epicardium of...

journal_title：Circulation

authors： Wijffels MC,Kirchhof CJ,Dorland R,Allessie MA

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Percutaneous transluminal coronary angioplasty (PTCA) is a widely used and important method of reperfusing coronary arteries. However, it is also associated with serious complications such as acute reocclusion and accelerated restenosis. The factors as well as the mechanisms involved in PTCA-associated compl...

journal_title：Circulation

authors： Brezinski DA,Nesto RW,Serhan CN

更新日期：1992-07-01 00:00:00

abstract：:To determine the effect of calcium-channel blockers on beta-adrenergic receptors, we studied the interactions of verapamil, diltiazem, and nifedipine with both human lymphocyte beta 2-adrenergic receptors and rat myocardial beta 1-adrenergic receptors by means of radioligand binding assays. We also determined the func...

journal_title：Circulation

authors： Feldman RD,Park GD,Lai CY

更新日期：1985-09-01 00:00:00

abstract：:The role of right ventricular (RV) fibrosis in pulmonary hypertension (PH) remains a subject of ongoing discussion. Alterations of the collagen network of the extracellular matrix may help prevent ventricular dilatation in the pressure-overloaded RV. At the same time, fibrosis impairs cardiac function, and a growing b...

journal_title：Circulation

authors： Andersen S,Nielsen-Kudsk JE,Vonk Noordegraaf A,de Man FS

更新日期：2019-01-08 00:00:00

abstract：BACKGROUND:Circulatory arrest (CA), which provides a bloodless field and good visualization without the need of aortic cross-clamp, is commonly used to facilitate repair of aortic lesions. However, extended periods of CA may impair cerebral metabolism and cause ischemic injury. Studies were performed to evaluate the ef...

journal_title：Circulation

authors： Lin PJ,Chang CH,Tan PP,Chang CN,Lee ST,Wang CC,Chang JP,Liu DW,Chu JJ,Tsai KT,Kao CL,Hsieh MJ,Hua MS

更新日期：1996-11-01 00:00:00