Emergencies in motoneuron disease.

Abstract:

:Genetic and acquired motor-neuron-disorders (MNDs) may undergo acute deterioration resulting in various emergency situations. This literature review aims at summarising and discussing current knowledge about emergencies in MNDs. Emergencies that have been reported in MND patients include: respiratory, bulbar, cardiac, septic, epileptic, psychiatric, pain-related, and traumatic emergencies. Emergencies due to respiratory insufficiency have the strongest impact on morbidity and mortality in MNDs. To optimise the management of emergencies in MNDs, it is recommended to discuss these topics with the patient prior to their occurrence. After informed consent, patients may indicate their decision by signing an advance directive as to how such emergencies should be managed in case they arise. Generally, treatment of emergencies in MNDs is not at variance from treatment of similar emergencies due to other causes, but some peculiarities need to be pointed out. It is concluded that patients with MNDs may experience various emergencies during the disease course. Management of these conditions should be discussed with the patient prior to their appearance. Management of these emergencies follows general guidelines, which widely vary between countries, and depend on the availability of a patient's advance directive.

journal_name

Intern Emerg Med

authors

Finsterer J,Stöllberger C

doi

10.1007/s11739-017-1644-6

subject

Has Abstract

pub_date

2017-08-01 00:00:00

pages

641-650

issue

5

eissn

1828-0447

issn

1970-9366

pii

10.1007/s11739-017-1644-6

journal_volume

12

pub_type

杂志文章,评审
  • Genetic and nutritional factors determining circulating levels of lipoprotein(a): results of the "Montignoso Study".

    abstract::Increasing evidence shows an association between high lipoprotein(a) [Lp(a)] levels and atherothrombotic diseases. Lp(a) trait is largely controlled by kringle-IV type 2 (KIV-2) size polymorphism in LPA gene, encoding for apo(a). Environmental factors are considered to determinate minor phenotypic variability in Lp(a)...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-020-02276-5

    authors: Sereni A,Sticchi E,Gori AM,Magi A,Della Latta D,Volta A,Murri A,Jamagidze G,Chiappino D,Abbate R,Gensini GF,Marcucci R,Sofi F,Giusti B

    更新日期:2020-10-01 00:00:00

  • New direct thrombin inhibitors.

    abstract::Direct thrombin inhibitors (DTIs) are a class of anticoagulants that bind selectively to thrombin and block its interaction with its substrates. Dabigatran etexilate and AZD0837, the new generation of DTIs, are now under intense development, and are potentially of great interest for internists. Dabigatran etexilate is...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-009-0314-8

    authors: Squizzato A,Dentali F,Steidl L,Ageno W

    更新日期:2009-12-01 00:00:00

  • Pneumonia in frail older patients: an up to date.

    abstract::Despite advances in diagnosis, antimicrobial therapy and supportive care modalities, community-acquired pneumonia (CAP) remains an important cause of morbidity and mortality, especially in patients who require hospitalization. Elderly patients with poor functional status are characterized by a higher risk of developin...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-012-0796-7

    authors: Falcone M,Blasi F,Menichetti F,Pea F,Violi F

    更新日期:2012-10-01 00:00:00

  • The effect of body mass index on intubation success rates and complications during emergency airway management.

    abstract::We evaluated the effect of body mass index (BMI) on intubation success rates and complications during emergency airway management. We retrospectively analyzed an airway registry at an academic medical center. The primary outcomes were the incidence of difficult intubation and complication rates, stratified by BMI. We ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-012-0874-x

    authors: Dargin JM,Emlet LL,Guyette FX

    更新日期:2013-02-01 00:00:00

  • A simple lung ultrasound protocol for the screening of COVID-19 pneumonia in the emergency department.

    abstract::The most relevant manifestation of coronavirus disease 2019 (COVID-19) is interstitial pneumonia. Several lung ultrasound (US) protocols for pneumonia diagnosis are used in clinical practice, but none has been proposed for COVID-19 patients' screening in the emergency department. We adopted a simplified 6-scan lung US...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-020-02596-6

    authors: Dacrema A,Silva M,Rovero L,Vertemati V,Losi G,Piepoli MF,Sacchi R,Mangiacotti M,Nazerian P,Pagani L,Tinelli V,Poggiali E,Bastoni D,Vercelli A,Magnacavallo A

    更新日期:2021-01-11 00:00:00

  • Impact of comorbidity on outcome in kidney transplant recipients: a retrospective study in Italy.

    abstract::The aim of this study was to relate in-hospital mortality (IHM), cardiovascular events (CVEs) and non-immunologic comorbidity evaluated on the basis of International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM) codification, in Italian kidney transplant recipients (KTRs). We evaluated IHM...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-016-1438-2

    authors: Fabbian F,De Giorgi A,Manfredini F,Lamberti N,Forcellini S,Storari A,Todeschini P,Gallerani M,La Manna G,Mikhailidis DP,Manfredini R

    更新日期:2016-09-01 00:00:00

  • Mechanical restraint in an emergency department: a consecutive series of 593 cases.

    abstract::The objective is to describe the characteristics of mechanically restrained patients in the emergency department (ED) of a university hospital and to evaluate the quality of restraint documentation that was filled out according to the dedicated protocol with respect to the law on restraint. All adult patients (≥16 yea...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-017-1697-6

    authors: Beysard N,Yersin B,Carron PN

    更新日期:2018-06-01 00:00:00

  • The prognostic role of gamma-glutamyltransferase activity in non-diabetic ST-elevation myocardial infarction.

    abstract::In patients with acute coronary syndrome, gamma-glutamyltransferase activity (GGT) proved to be an independent predictor of the development of major adverse cardiac events at early and long terms. No data are available on GGT in ST-elevation myocardial infarction (STEMI). We assessed, in 337 consecutive STEMI patients...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-010-0464-8

    authors: Lazzeri C,Valente S,Tarquini R,Chiostri M,Picariello C,Gensini GF

    更新日期:2011-06-01 00:00:00

  • Drug-drug interactions in patients with acute coronary syndrome across phases of treatment.

    abstract::The objective of this study is to evaluate potential drug-drug interactions (pDDIs) and risk factors for pDDIs in three phases of an acute coronary syndrome (ACS) treatment: from the point of first medical contact to the coronary angiography (first phase), after coronary angiography to the last day of hospitalization ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-018-1994-8

    authors: Pejčić AV,Janković SM,Davidović G

    更新日期:2019-04-01 00:00:00

  • Clinical assessment of endothelial function in patients with chronic obstructive pulmonary disease: a systematic review with meta-analysis.

    abstract::Patients with chronic obstructive pulmonary disease (COPD) have an increased cardiovascular morbidity and mortality. Flow-mediated (FMD) and nitrate-mediated dilatation (NMD) are considered non-invasive methods to assess endothelial function and surrogate markers of subclinical atherosclerosis. We performed a systemat...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-017-1690-0

    authors: Ambrosino P,Lupoli R,Iervolino S,De Felice A,Pappone N,Storino A,Di Minno MND

    更新日期:2017-09-01 00:00:00

  • Transjugular intrahepatic portosystemic shunt (TIPS): current indications and strategies to improve the outcomes.

    abstract::Transjugular intrahepatic portosystemic shunt (TIPS) represents a very effective treatment of complications of portal hypertension. Established indications to TIPS in cirrhotic patients include portal hypertensive bleeding and refractory ascites. Over the years additional indications have been proposed, such as the tr...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-019-02252-8

    authors: Vizzutti F,Schepis F,Arena U,Fanelli F,Gitto S,Aspite S,Turco L,Dragoni G,Laffi G,Marra F

    更新日期:2020-01-01 00:00:00

  • A comparison amongst three rapid urease tests to diagnose Helicobacter pylori infection in 375 consecutive dyspeptic.

    abstract::Rapid diagnostic tools for Helicobacter pylori are important in endoscopy. To assess the accuracy of a new 5-min rapid urease test (UFT300, ABS Cernusco, sul Naviglio, Italy) compared with the 1-h Pyloritek (Serim Laboratories, Elkhart, IN) and the 24-h CLO test (Kimberly-Clark Ballard Medical Products, Roswell, GA), ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-009-0344-2

    authors: Vaira D,Gatta L,Ricci C,Perna F,Saracino I,Fiorini G,Castelli V,Holton J

    更新日期:2010-02-01 00:00:00

  • Physician in triage improves emergency department patient throughput.

    abstract::To determine if a physician in triage (PIT) improves Emergency Department (ED) patient flow in a community teaching hospital. This is an interventional study comparing patient flow parameters for the 3-month periods before and after implementation of a PIT model. During the interventional time an additional attending ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-012-0839-0

    authors: Imperato J,Morris DS,Binder D,Fischer C,Patrick J,Sanchez LD,Setnik G

    更新日期:2012-10-01 00:00:00

  • Subclinical hyperthyroidism and cardiovascular manifestations: a reevaluation of the association.

    abstract::Subclinical hyperthyroidism (SH) has been reported associated with atrial fibrillation (AF), heart failure (HF) and coronary heart disease events, including mortality. An expert opinion indicates that AF is the possible link between SH and the other important cardiovascular (CV) manifestations. We analyzed the data of...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-013-0913-2

    authors: Carpi A,Cini G,Russo M,Antonelli A,Gaudio C,Galetta F,Franzoni F,Rossi G

    更新日期:2013-04-01 00:00:00

  • Is there a link between venous and arterial thrombosis? A reappraisal.

    abstract::Whether there is a link between venous and arterial thrombotic disorders is still a matter of debate. They share common risk factors, such as old age, male sex and obesity. Endothelial dysfunction and inflammation are likely to play a role in determining the simultaneous involvement of the two vascular compartments. U...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-019-02238-6

    authors: Prandoni P

    更新日期:2020-01-01 00:00:00

  • Extreme hypomagnesemia: characteristics of 119 consecutive inpatients.

    abstract::Extreme hypomagnesemia (hypoMg) can be encountered in many situations, but little data currently exist. Our aim is to describe the epidemiological, clinical, etiological characteristics, and the biological abnormalities of consecutive inpatients with extreme hypomagnesemia. In our observational monocentric study, betw...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-018-1898-7

    authors: Cheminet G,Clain G,Jannot AS,Ranque B,Passeron A,Michon A,De Luna G,Diehl JL,Oudard S,Cellier C,Karras A,Vedié B,Prot-Bertoye C,Pouchot J,Arlet JB

    更新日期:2018-12-01 00:00:00

  • Safety and efficacy of sucrosomial iron in inflammatory bowel disease patients with iron deficiency anemia.

    abstract::Iron deficiency anemia (IDA) is one of the most common complications of inflammatory bowel disease (IBD). We planned a prospective study to address tolerability and efficacy of sucrosomial iron, a new oral formulation of ferric pyrophosphate, in IBD patients. Thirty patients with a confirmed diagnosis of Crohn's Disea...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-018-1993-9

    authors: Abbati G,Incerti F,Boarini C,Pileri F,Bocchi D,Ventura P,Buzzetti E,Pietrangelo A

    更新日期:2019-04-01 00:00:00

  • Association of physician experience with a higher prescription rate of anti-influenza agents in low-risk patients.

    abstract::During the influenza season, most patients suspected of having influenza undergo rapid influenza diagnostic tests (RIDTs) in Japan despite their low sensitivity. However, the physician's actual rationale for prescribing antivirals, besides the results of RIDTs, remains poorly understood. Our study sought to identify t...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-020-02570-2

    authors: Nakajima K,Akebo H,Tsugihashi Y,Ishimaru H,Sada R

    更新日期:2021-01-02 00:00:00

  • Treatment outcome in a cohort of young patients with polycythemia vera.

    abstract::The treatment of polycythemia vera in young adults is challenging, requiring one to run a balance between the increased risk of vascular complications, if left untreated, versus the potential of promoting secondary leukemia/myelodysplasia or cancer, if actively managed with chemotherapy. We report the results of a 20-...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-010-0429-y

    authors: Ruggeri M,Finotto S,Fortuna S,Rodeghiero F

    更新日期:2010-10-01 00:00:00

  • Diagnosis and management of acute aortic syndromes in the emergency department.

    abstract::Acute aortic syndromes (AASs) are deadly cardiovascular emergencies involving the thoracic aorta. AASs are relatively rare conditions, have unspecific signs and symptoms (including truncal pain, syncope, neurologic deficit and limb ischemia) and require contrast-enhanced tomography angiography (CTA) of the chest and a...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-020-02354-8

    authors: Morello F,Santoro M,Fargion AT,Grifoni S,Nazerian P

    更新日期:2021-01-01 00:00:00

  • Inflammatory biomarkers and coronary heart disease: from bench to bedside and back.

    abstract::Inflammation plays a pivotal role in all stages of atherosclerosis from endothelial dysfunction and plaque formation to plaque destabilization and disruption. Inflammatory biomarkers, originally studied to better understand the pathophysiology of atherosclerosis, have generated increasing interest among clinicians, be...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-010-0361-1

    authors: Biasillo G,Leo M,Della Bona R,Biasucci LM

    更新日期:2010-06-01 00:00:00

  • Validation of the Italian version of a new coma scale: the FOUR score.

    abstract::The Glasgow Coma Scale (GCS) is the most widely accepted tool for the evaluation of consciousness, despite several reported shortcomings. A new coma scale, named Full Outline of UnResponsiveness (FOUR) score, is now available. The aim of the present study is to provide and validate the Italian version of the FOUR scor...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-011-0583-x

    authors: Marcati E,Ricci S,Casalena A,Toni D,Carolei A,Sacco S

    更新日期:2012-04-01 00:00:00

  • Halitosis: could it be more than mere bad breath?

    abstract::Halitosis is a generic term used to describe unpleasant odor emanating from the mouth air and breath, independent of the source where the odor substances originate. It affects between 50 and 65% of the population, but despite its frequency, this problem is often unaccepted and declared as taboo. Ninety percent of pati...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-010-0492-4

    authors: Campisi G,Musciotto A,Di Fede O,Di Marco V,Craxì A

    更新日期:2011-08-01 00:00:00

  • Prevalence and prognostic impact of left ventricular non-compaction in patients with thalassemia.

    abstract::A high incidence of isolated left ventricular non-compaction (LVNC) has been reported in previous studies on smaller cohorts of patients with thalassemia by cardiac MRI but the clinical impact of the finding is unknown. This prospective cohort study evaluates the prevalence and clinical implication of the finding. Pro...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-019-02114-3

    authors: Bonamini R,Imazio M,Faletti R,Gatti M,Xhyheri B,Limone M,Longo F,Piga A

    更新日期:2019-11-01 00:00:00

  • Six minute walk test: a simple and useful test to evaluate functional capacity in patients with heart failure.

    abstract::In heart failure survival is closely related to functional capacity. Peak O2 consumption at cardiopulmonary exercise test (CPET) is considered the gold standard for the evaluation of exercise tolerance. Since >70% of patients with heart failure, usually elderly or with significant comorbidities, are referred to Depart...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审

    doi:10.1007/s11739-008-0130-6

    authors: Rostagno C,Gensini GF

    更新日期:2008-09-01 00:00:00

  • Point-of-care ultrasound modalities in terms of diagnosing acute decompensated heart failure in emergency department; a diagnostic accuracy study.

    abstract::This study aimed to compare the diagnostic accuracy of heart, lung and inferior vena cava (IVC) ultrasonography modalities, alone and combined, for possible added accuracy in diagnosing acute decompensated heart failure (ADHF), in a group of patients with the final diagnosis of ADHF based on plasma level of B-type nat...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-019-02233-x

    authors: Farahmand S,Abdolhoseini A,Aliniagerdroudbari E,Babaniamansour S,Baratloo A,Bagheri-Hariri S

    更新日期:2020-04-01 00:00:00

  • Early invasive strategy and outcomes of non-ST-elevation acute coronary syndrome patients: is time really the major determinant?

    abstract::In non-ST-elevation acute coronary syndromes (ACS), an early invasive strategy is recommended for middle/high-risk patients; however, the optimal timing for coronary angiography is still debated. The aim of this study was to evaluate the prognostic implications of the time of angiography in ACS patients treated in acc...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-011-0596-5

    authors: Giglioli C,Cecchi E,Landi D,Valente S,Chiostri M,Romano SM,Spini V,Perrotta L,Simonetti I,Gensini GF

    更新日期:2013-03-01 00:00:00

  • Therapeutic oligonucleotides in cardiovascular and metabolic diseases: insights for the internist.

    abstract::The idea of using small RNA fragments (oligonucleotides) for therapeutic purposes dates back to the 1990s, following the landmark discoveries on the mechanisms of gene silencing and RNA-interference (RNA-i). However, the first applications in medicine were hampered by difficulties in chemical stabilization and efficie...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-018-1810-5

    authors: Girelli D,Busti F,Marchi G,Martinelli N,Olivieri O

    更新日期:2018-04-01 00:00:00

  • A meta-analysis of randomized controlled trials: combination of ketamine and propofol versus ketamine alone for procedural sedation and analgesia in children.

    abstract::Although ketamine has been used for procedural sedation and analgesia, some researchers have assessed ketamine-propofol as a better alternative because of its reduced adverse events. The goal of this review was to compare adverse events between ketamine-propofol and ketamine for procedural sedation and analgesia in ch...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,meta分析

    doi:10.1007/s11739-019-02173-6

    authors: Hu Y,Xu W,Cao F

    更新日期:2019-10-01 00:00:00

  • Correlation between religion and hypertension.

    abstract::The objectives of the study were to investigate the relationship between religion and hypertension, as well as the theoretical mechanism through which religion exerts effect on hypertension. A MEDLINE literature search was performed on articles describing religion and hypertension (N = 543) excluding unqualified ones ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章

    doi:10.1007/s11739-018-1791-4

    authors: Meng Q,Zhang X,Shi R,Liao H,Chen X

    更新日期:2019-03-01 00:00:00