Emergencies in motoneuron disease.


:Genetic and acquired motor-neuron-disorders (MNDs) may undergo acute deterioration resulting in various emergency situations. This literature review aims at summarising and discussing current knowledge about emergencies in MNDs. Emergencies that have been reported in MND patients include: respiratory, bulbar, cardiac, septic, epileptic, psychiatric, pain-related, and traumatic emergencies. Emergencies due to respiratory insufficiency have the strongest impact on morbidity and mortality in MNDs. To optimise the management of emergencies in MNDs, it is recommended to discuss these topics with the patient prior to their occurrence. After informed consent, patients may indicate their decision by signing an advance directive as to how such emergencies should be managed in case they arise. Generally, treatment of emergencies in MNDs is not at variance from treatment of similar emergencies due to other causes, but some peculiarities need to be pointed out. It is concluded that patients with MNDs may experience various emergencies during the disease course. Management of these conditions should be discussed with the patient prior to their appearance. Management of these emergencies follows general guidelines, which widely vary between countries, and depend on the availability of a patient's advance directive.


Intern Emerg Med


Finsterer J,Stöllberger C




Has Abstract


2017-08-01 00:00:00














  • The utility of head computed tomography in the emergency department evaluation of syncope.

    abstract:OBJECTIVE:Current guidelines for evaluation of syncope recommend that in the absence of objective focal neurologic findings, head computed tomography (HCT) may not be necessary. Compliance with this recommendation is highly variable, which may be due in part to the lack of currently available evidence. We undertook the...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Goyal N,Donnino MW,Vachhani R,Bajwa R,Ahmad T,Otero R

    更新日期:2006-01-01 00:00:00

  • Association between in-hospital acute hypertensive episodes and outcomes in older trauma patients.

    abstract::Although chronic hypertension is associated with long-term complications, few studies directly examine the effects of in-hospital acute hypertensive episodes in trauma patients. The aim was to determine whether there is an association between in-hospital acute hypertension and morbidity. We included trauma patients be...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Saliba L,Stawicki SP,Thongrong C,Bergese SD,Papadimos TJ,Gerlach AT

    更新日期:2014-08-01 00:00:00

  • Point-of-care ultrasound modalities in terms of diagnosing acute decompensated heart failure in emergency department; a diagnostic accuracy study.

    abstract::This study aimed to compare the diagnostic accuracy of heart, lung and inferior vena cava (IVC) ultrasonography modalities, alone and combined, for possible added accuracy in diagnosing acute decompensated heart failure (ADHF), in a group of patients with the final diagnosis of ADHF based on plasma level of B-type nat...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Farahmand S,Abdolhoseini A,Aliniagerdroudbari E,Babaniamansour S,Baratloo A,Bagheri-Hariri S

    更新日期:2020-04-01 00:00:00

  • Subclinical hyperthyroidism and cardiovascular manifestations: a reevaluation of the association.

    abstract::Subclinical hyperthyroidism (SH) has been reported associated with atrial fibrillation (AF), heart failure (HF) and coronary heart disease events, including mortality. An expert opinion indicates that AF is the possible link between SH and the other important cardiovascular (CV) manifestations. We analyzed the data of...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审


    authors: Carpi A,Cini G,Russo M,Antonelli A,Gaudio C,Galetta F,Franzoni F,Rossi G

    更新日期:2013-04-01 00:00:00

  • Quality of life impairment in Behçet's disease and relationship with disease activity: a prospective study.

    abstract::Our aim was to prospectively investigate the impact of Behçet's disease (BD), disease activity, and clinical and demographic characteristics on different aspects of quality of life (QoL) measured by the short-form (SF)-36 QoL scale. We administered the SF-36 to 37 consecutive BD patients in different moments of diseas...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Fabiani C,Vitale A,Orlando I,Sota J,Capozzoli M,Franceschini R,Galeazzi M,Tosi GM,Frediani B,Cantarini L

    更新日期:2017-10-01 00:00:00

  • Validation of the Italian version of a new coma scale: the FOUR score.

    abstract::The Glasgow Coma Scale (GCS) is the most widely accepted tool for the evaluation of consciousness, despite several reported shortcomings. A new coma scale, named Full Outline of UnResponsiveness (FOUR) score, is now available. The aim of the present study is to provide and validate the Italian version of the FOUR scor...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Marcati E,Ricci S,Casalena A,Toni D,Carolei A,Sacco S

    更新日期:2012-04-01 00:00:00

  • NIV by an interdisciplinary respiratory care team in severe respiratory failure in the emergency department limited to day time hours.

    abstract::Non-invasive ventilatory support is frequently used in patients with severe respiratory failure (SRF), but is often limited to intensive care units (ICU). We hypothesized that an instantaneous short course of NIV (up to 2 h), limited to regular working hours as an additional therapy on the emergency department (ED) wo...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Horvath CM,Brutsche MH,Schoch OD,Schillig B,Baty F,vonOw D,Rüdiger JJ

    更新日期:2017-12-01 00:00:00

  • Cardiovascular oncology: a new discipline inside internal medicine?

    abstract::Cardiovascular disease and cancer incidence and prevalence have risen over the past few decades to become the leading causes of death. On the one hand, cancer patients will be treated with cardiotoxic chemotherapies; on the other, cardiovascular patients will receive a new diagnosis of cancer and will have to face tre...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Prisco D,D'Elios MM,Cenci C,Ciucciarelli L,Tamburini C

    更新日期:2014-06-01 00:00:00

  • Prevalence, predictors and prognostic significance of microalbuminuria in acute cardiac patients: a single center experience.

    abstract::The objective of this study was to prospectively assess the prevalence, predictors and prognostic significance of microalbuminuria in a large cohort of consecutive acute cardiac patients, admitted to an intensive cardiac care unit from 1 January 2008 to 30 June 2009. In 815 acute cardiac patients, microalbuminuria is ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Valente S,Lazzeri C,Chiostri M,Alterini B,Ognibene A,Giglioli C,Pigozzi C,Gensini GF

    更新日期:2013-06-01 00:00:00

  • Thrombin generation in plasma from patients with cirrhosis supplemented with normal plasma: considerations on the efficacy of treatment with fresh-frozen plasma.

    abstract::Cirrhosis is characterized by a complex coagulation defect leading to the prolongation of the prothrombin and activated partial thromboplastin times (PT and APTT). Arbitrary PT cut-off values are still used as a yardstick to guide treatment with fresh-frozen plasma (FFP) or other pro-coagulant agents in patients under...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Tripodi A,Chantarangkul V,Primignani M,Clerici M,Dell'era A,Aghemo A,Mannucci PM

    更新日期:2012-04-01 00:00:00

  • Splanchnic vein thrombosis: clinical presentation, risk factors and treatment.

    abstract::The term splanchnic vein thrombosis encompasses Budd-Chiari syndrome (BCS), extrahepatic portal vein obstruction (EHPVO), and mesenteric vein thrombosis; the simultaneous involvement of additional regions is frequent, and clinical presentations and risk factors may be shared. The annual incidence of BCS and isolated m...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审


    authors: De Stefano V,Martinelli I

    更新日期:2010-12-01 00:00:00

  • An attempt to measure the spread of emergency medicine internationally.

    abstract:OBJECTIVE:To determine the feasibility of using the internet to track the spread of emergency medicine internationally. METHODS: OVERVIEW:This was an attempt to perform a descriptive cross-sectional study employing a web-based survey. SUBJECTS:Potential respondents were identified from multiple sources. OBSERVATION...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Nagurney JT,Huang C,Kulkarni RG,Sane S,Davis MA,Anderson PD,Gaufberg SV,Ciottone GR,Motola I,Chang Y,Setnik G

    更新日期:2007-12-01 00:00:00

  • Predictors of hospital readmission 1 year after ischemic stroke.

    abstract::Predictors of short-term readmission after ischemic stroke have been previously identified, but few studies analyzed predictors of long-term readmission, namely early imaging findings and treatment with intravenous thrombolysis (IVT). To characterize predictors of hospital readmission during the first year after hospi...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Leitão A,Brito A,Pinho J,Alves JN,Costa R,Amorim JM,Ribeiro M,Pinho I,Ferreira C

    更新日期:2017-02-01 00:00:00

  • Management of idiopathic recurrent pericarditis in adults and in children: a role for IL-1 receptor antagonism.

    abstract::Recurrent pericarditis is one of the most frequent pericardial diseases, affecting up to 30% of the patients who have experienced acute pericarditis. While the diagnosis of acute pericarditis is sometime straight forward, its etiology and therapeutic management are still a challenge for physicians. In developed countr...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审


    authors: Brucato A,Emmi G,Cantarini L,Di Lenarda A,Gattorno M,Lopalco G,Marcolongo R,Imazio M,Martini A,Prisco D

    更新日期:2018-06-01 00:00:00

  • Therapeutic induced hypothermia does not improve the prognosis of out-of-hospital cardiac arrest patients.

    abstract::Unconscious patients admitted to critical care units after out-of-hospital cardiac arrest are at high risk for death, and neurologic deficits are common among those who survive. The target temperature management (TTM), 33 vs. 36 °C, after out-of-hospital cardiac arrest trial was conducted to assess the benefits and ha...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,随机对照试验


    authors: Granberg B,McGillis E,Solbiati M,Gruppo di Autoformazione Metodologica (GrAM).

    更新日期:2014-09-01 00:00:00

  • New direct thrombin inhibitors.

    abstract::Direct thrombin inhibitors (DTIs) are a class of anticoagulants that bind selectively to thrombin and block its interaction with its substrates. Dabigatran etexilate and AZD0837, the new generation of DTIs, are now under intense development, and are potentially of great interest for internists. Dabigatran etexilate is...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Squizzato A,Dentali F,Steidl L,Ageno W

    更新日期:2009-12-01 00:00:00

  • Clinical characteristics and outcomes of patients with extended-spectrum β-lactamase-producing bacteremias in the emergency department.

    abstract::Extended-spectrum β-lactamase (ESBL)-producing bacteria have been spreading from hospitals to communities. Despite this, there are limited emergency department (ED) patient-based studies about these bacteremias. A retrospective matched case-control study with a ratio of 1:3 was conducted at a university hospital. The ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Lin JN,Chen YH,Chang LL,Lai CH,Lin HL,Lin HH

    更新日期:2011-12-01 00:00:00

  • Comparison of lercanidipine plus hydrochlorothiazide vs. lercanidipine plus enalapril on micro and macrocirculation in patients with mild essential hypertension.

    abstract::Dihydropyridine calcium channel blockers may possess antioxidant properties, and might improve micro and macrovascular structure and function. Combination treatment with an ACE inhibitor may have additional advantages, compared with a thiazide diuretic. The aim of the present study is to investigate the effects of a s...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: De Ciuceis C,Salvetti M,Paini A,Rossini C,Muiesan ML,Duse S,Caletti S,Coschignano MA,Semeraro F,Trapletti V,Bertacchini F,Brami V,Petelca A,Agabiti Rosei E,Rizzoni D,Agabiti Rosei C

    更新日期:2017-10-01 00:00:00

  • Changes in erythropoiesis, iron metabolism and oxidative stress after half-marathon.

    abstract:OBJECTIVE:In marathon runners changes in red blood cell count, haematocrit and haemoglobin in relation to haemodilution have been reported. Moreover, it has been hypothesized that strenuous exercise induces oxidant stress through several different mechanisms. This study investigated the haematological variables, iron s...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Duca L,Da Ponte A,Cozzi M,Carbone A,Pomati M,Nava I,Cappellini MD,Fiorelli G

    更新日期:2006-01-01 00:00:00

  • Association between hemoglobin levels and clinical outcomes in adult patients after in-hospital cardiac arrest: a retrospective cohort study.

    abstract::In addition to cardiac output, oxygen delivery is determined by the amount of oxygen carried by hemoglobin, which is estimated by the product of hemoglobin level and peripheral hemoglobin oxygen saturation (SpO2). Optimal hemoglobin concentration for post-cardiac arrest syndrome (PCAS) has not yet been investigated th...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Wang CH,Huang CH,Chang WT,Tsai MS,Yu PH,Wang AY,Chen NC,Chen WJ

    更新日期:2016-08-01 00:00:00

  • Failure to achieve first attempt success at intubation using video laryngoscopy is associated with increased complications.

    abstract::The purpose of this investigation was to investigate the association between first attempt success and intubation-related complications in the Intensive Care Unit after the widespread adoption of video laryngoscopy. We further sought to characterize and identify the predictors of complications that occur despite first...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Hypes C,Sakles J,Joshi R,Greenberg J,Natt B,Malo J,Bloom J,Chopra H,Mosier J

    更新日期:2017-12-01 00:00:00

  • The effect of management models on thromboembolic and bleeding rates in anticoagulated patients: an ecological study.

    abstract::The primary study objective is to compare the outcomes of patients taking oral anticoagulant medications in two distinct populations treated according to different management models (comprehensive vs. usual care). (Design: regional prospective cohort study; setting: hospital admission data from two regions). Eligible ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Tosetto A,Testa S,Palareti G,Paoletti O,Nichele I,Catalano F,Morandini R,Di Paolo M,Tala M,Esteban P,Cora' F,Mannino S,Maroni A,Sessa M,Castaman G

    更新日期:2019-11-01 00:00:00

  • Subclinical liver fibrosis in patients with idiopathic pulmonary fibrosis.

    abstract::Data on the presence of subclinical fibrosis across multiple organs in patients with idiopathic lung fibrosis (IPF) are lacking. Our study aimed at investigating through hepatic transient elastography (HTE) the prevalence and clinical impact of subclinical liver fibrosis in a cohort of patients with IPF. Patients refe...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Cocconcelli E,Tonelli R,Abbati G,Marchioni A,Castaniere I,Pelizzaro F,Russo FP,Vegetti A,Balestro E,Pietrangelo A,Richeldi L,Luppi F,Spagnolo P,Clini E,Cerri S

    更新日期:2020-05-25 00:00:00

  • Intracranial bruits in meningitis.

    abstract::Intracranial bruits (ICB) are faint, high-pitched, and mostly heard on the orbit in the systolic phase of the cardiovascular cycle. This report discusses a case of Listeria monocytogenes meningitis in a 17-month-old male patient in whom ICB were auscultated. ICB is thought to be caused by compression of blood vessels ...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Sugiura K,Ihara T

    更新日期:2021-01-03 00:00:00

  • The influence of early-life conditions on cardiovascular disease later in life among ethnic minority populations: a systematic review.

    abstract::Ethnic minority groups are disproportionately affected by cardiovascular diseases (CVDs). The reasons for the high prevalence of CVD in ethnic minority groups are not fully understood. Recently, the importance of early-life developmental factors and their impact on CVDs in adulthood is increasingly being recognised, b...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审


    authors: Bijker R,Agyemang C

    更新日期:2016-04-01 00:00:00

  • A simple lung ultrasound protocol for the screening of COVID-19 pneumonia in the emergency department.

    abstract::The most relevant manifestation of coronavirus disease 2019 (COVID-19) is interstitial pneumonia. Several lung ultrasound (US) protocols for pneumonia diagnosis are used in clinical practice, but none has been proposed for COVID-19 patients' screening in the emergency department. We adopted a simplified 6-scan lung US...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Dacrema A,Silva M,Rovero L,Vertemati V,Losi G,Piepoli MF,Sacchi R,Mangiacotti M,Nazerian P,Pagani L,Tinelli V,Poggiali E,Bastoni D,Vercelli A,Magnacavallo A

    更新日期:2021-01-11 00:00:00

  • Pneumonia in frail older patients: an up to date.

    abstract::Despite advances in diagnosis, antimicrobial therapy and supportive care modalities, community-acquired pneumonia (CAP) remains an important cause of morbidity and mortality, especially in patients who require hospitalization. Elderly patients with poor functional status are characterized by a higher risk of developin...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章,评审


    authors: Falcone M,Blasi F,Menichetti F,Pea F,Violi F

    更新日期:2012-10-01 00:00:00

  • E-cigarette use is strongly associated with recent smoking cessation: an analysis of a representative population sample in Greece.

    abstract::The purpose was to examine the association between e-cigarette use and smoking cessation according to quit duration in Greece in 2017. A cross-sectional survey of a representative sample of adults living in Attica prefecture was performed in May 2017 through telephone interviews. The present analysis was confined to c...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Farsalinos K,Siakas G,Poulas K,Voudris V,Merakou K,Barbouni A

    更新日期:2019-09-01 00:00:00

  • Direct oral anticoagulants in atrial fibrillation: can data from randomized clinical trials be safely transferred to the general population? Yes.

    abstract::Atrial fibrillation is the most common arrhythmia and is associated with significant morbidity and mortality. The current therapeutic options for patients at high thromboembolic risk include the vitamin K antagonists and the direct oral anticoagulants. These novel agents have been evaluated in more than 40,000 patient...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Riva N,Ageno W

    更新日期:2015-09-01 00:00:00

  • Use of a risk nomogram to predict emergency department reattendance in older people after discharge: a validation study.

    abstract::In older people, revisit to the emergency department (ED) in the short period after discharge is not entirely avoidable, but in a proportion of cases is preventable, and should ideally be minimised. We have previously derived a risk probability nomogram to predict the likelihood of revisit. In this study, we sought to...

    journal_title:Internal and emergency medicine

    pub_type: 杂志文章


    authors: Arendts G,Etherton-Beer C,Jones R,Bullow K,MacDonald E,Dumas S,Parker D,Hutton M,Burrows S,Brown SG,Almeida OP

    更新日期:2015-06-01 00:00:00