Abstract:
:There is a need for more information on the quality of life (QoL) in patients undergoing chemotherapy. We wanted to investigate the perception of health status in colon cancer patients before, 3 and 6 months after chemotherapy. A secondary purpose was to assess the different perceptions of QoL between men and women during and after adjuvant or palliative therapy. We investigated 100 patients throughout chemotherapy for colon cancer. Data were collected through the SF-36 questionnaire. The score of all variables analyzed in the study group was lower than in the control group, which indicates a lower performance status, more marked in the female sex. Patients were then subdivided by the state of disease (localized or metastatic) and the variables, were evaluated before, 3 and 6 months after therapy. In patients treated with adjuvant treatment, there was a worsening of the performance status, followed by an increase after 6 months. We found that after 3 months of therapy, affected male patients perceived more limitations in carrying out their work, other daily activities and social relationships, owing to both their emotional state and their physical health. In metastatic patients the values of the eight variables decreased dramatically after 6 months, indicating a worsening of the QoL. In patients who received adjuvant treatment there was a certain worsening of the health status at 3 months, followed by a general improvement after 6 months. This improvement was not observed in patients undergoing palliative therapy. Several differences were observed between men and women in performance status after treatment.
journal_name
Intern Emerg Medjournal_title
Internal and emergency medicineauthors
Domati F,Luppi G,Reggiani-Bonetti L,Zironi S,Depenni R,Fontana A,Gelsomino F,de Leon MPdoi
10.1007/s11739-014-1174-4subject
Has Abstractpub_date
2015-06-01 00:00:00pages
423-9issue
4eissn
1828-0447issn
1970-9366journal_volume
10pub_type
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journal_title:Internal and emergency medicine
pub_type: 杂志文章,评审
doi:10.1007/s11739-020-02354-8
更新日期:2021-01-01 00:00:00
abstract::Up to 10% of all patients at the Emergency Department present for acute abdominal pain. The C-reactive protein (CRP) and white blood cell (WBC) are routinely determined as part of the workup of patients with abdominal pain. Three large prospective cohort studies comprising a total of 2961 adult patients with acute abd...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-015-1333-2
更新日期:2016-02-01 00:00:00
abstract::Use of etomidate in severe sepsis and septic shock has been challenged in recent literature due to its link to adrenal insufficiency and suspected increased mortality. We hypothesized that etomidate does not contribute to mortality in this patient population. A retrospective chart review of 230 intubated, severe sepsi...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-011-0553-3
更新日期:2011-06-01 00:00:00
abstract::Chronic hypersensitivity pneumonitis (cHP) is a fibrotic interstitial lung disease (ILD) resulting from inhalation of different organic substances and chemical compounds determining an inflammatory and immunological response in sensitized individuals. KL-6, a human mucin protein expressed by type 2 pneumocytes, has be...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-020-02281-8
更新日期:2020-10-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-018-1898-7
更新日期:2018-12-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-016-1407-9
更新日期:2016-09-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章,评审
doi:10.1007/s11739-013-0913-2
更新日期:2013-04-01 00:00:00
abstract::In a Coronavirus disease 2019 (COVID-19) epidemic, management of the emergency department is a difficult task in terms of prevention and control of the disease in general hospitals. On top of meeting urgent needs of patients for medical treatment, the emergency department also has to devote resources into investigatio...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-020-02499-6
更新日期:2020-11-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-011-0596-5
更新日期:2013-03-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-014-1104-5
更新日期:2015-02-01 00:00:00
abstract::Transjugular intrahepatic portosystemic shunt (TIPS) represents a very effective treatment of complications of portal hypertension. Established indications to TIPS in cirrhotic patients include portal hypertensive bleeding and refractory ascites. Over the years additional indications have been proposed, such as the tr...
journal_title:Internal and emergency medicine
pub_type: 杂志文章,评审
doi:10.1007/s11739-019-02252-8
更新日期:2020-01-01 00:00:00
abstract::In patients with acute coronary syndrome, gamma-glutamyltransferase activity (GGT) proved to be an independent predictor of the development of major adverse cardiac events at early and long terms. No data are available on GGT in ST-elevation myocardial infarction (STEMI). We assessed, in 337 consecutive STEMI patients...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-010-0464-8
更新日期:2011-06-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-020-02539-1
更新日期:2020-11-05 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-016-1546-z
更新日期:2017-12-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-020-02287-2
更新日期:2020-03-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/BF02936543
更新日期:2006-01-01 00:00:00
abstract::Our aim was to prospectively investigate the impact of Behçet's disease (BD), disease activity, and clinical and demographic characteristics on different aspects of quality of life (QoL) measured by the short-form (SF)-36 QoL scale. We administered the SF-36 to 37 consecutive BD patients in different moments of diseas...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-017-1691-z
更新日期:2017-10-01 00:00:00
abstract::Extended-spectrum β-lactamase (ESBL)-producing bacteria have been spreading from hospitals to communities. Despite this, there are limited emergency department (ED) patient-based studies about these bacteremias. A retrospective matched case-control study with a ratio of 1:3 was conducted at a university hospital. The ...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-011-0707-3
更新日期:2011-12-01 00:00:00
abstract::Intracranial bruits (ICB) are faint, high-pitched, and mostly heard on the orbit in the systolic phase of the cardiovascular cycle. This report discusses a case of Listeria monocytogenes meningitis in a 17-month-old male patient in whom ICB were auscultated. ICB is thought to be caused by compression of blood vessels ...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-020-02579-7
更新日期:2021-01-03 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 社论
doi:10.1007/s11739-014-1154-8
更新日期:2015-03-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-015-1219-3
更新日期:2015-06-01 00:00:00
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journal_title:Internal and emergency medicine
pub_type: 杂志文章,已发布勘误
doi:10.1007/s11739-018-1921-z
更新日期:2018-09-01 00:00:00
abstract::Dihydropyridine calcium channel blockers may possess antioxidant properties, and might improve micro and macrovascular structure and function. Combination treatment with an ACE inhibitor may have additional advantages, compared with a thiazide diuretic. The aim of the present study is to investigate the effects of a s...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-017-1696-7
更新日期:2017-10-01 00:00:00
abstract::Atrial fibrillation is the most common arrhythmia and is associated with significant morbidity and mortality. The current therapeutic options for patients at high thromboembolic risk include the vitamin K antagonists and the direct oral anticoagulants. These novel agents have been evaluated in more than 40,000 patient...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-015-1277-6
更新日期:2015-09-01 00:00:00
abstract::In recent years, thanks to the development of miniaturized ultrasound devices, comparable to personal computers, tablets and even to smart phones, we have seen an increasing use of bedside ultrasound in internal medicine departments as a novel kind of ultrasound stethoscope. The clinical ultrasound-assisted approach h...
journal_title:Internal and emergency medicine
pub_type: 杂志文章,评审
doi:10.1007/s11739-014-1113-4
更新日期:2014-10-01 00:00:00
abstract::In chronic heart failure (CHF), neurohumoral systems, which help to maintain circulatory homeostasis, are maladaptive and responsible for disease progression and congestion in the long term. The activation of sympathetic hormones and renin-angiotensin-aldosterone system (RAAS), in addition to non-osmotic vasopressin r...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-011-0674-8
更新日期:2011-10-01 00:00:00
abstract::The direct oral anticoagulants (DOACs) are drugs used in clinical practice since 2009 for the prevention of stroke or systemic embolism in non-valvular atrial fibrillation, and for the treatment and secondary prevention of venous thromboembolism. The four DOACs, including the three factor Xa inhibitors (rivaroxaban, a...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-017-1628-6
更新日期:2017-04-01 00:00:00
abstract::A high incidence of isolated left ventricular non-compaction (LVNC) has been reported in previous studies on smaller cohorts of patients with thalassemia by cardiac MRI but the clinical impact of the finding is unknown. This prospective cohort study evaluates the prevalence and clinical implication of the finding. Pro...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-019-02114-3
更新日期:2019-11-01 00:00:00
abstract::The objective of this study was to prospectively assess the prevalence, predictors and prognostic significance of microalbuminuria in a large cohort of consecutive acute cardiac patients, admitted to an intensive cardiac care unit from 1 January 2008 to 30 June 2009. In 815 acute cardiac patients, microalbuminuria is ...
journal_title:Internal and emergency medicine
pub_type: 杂志文章
doi:10.1007/s11739-011-0619-2
更新日期:2013-06-01 00:00:00
abstract::General concepts about medical disasters, public health and triage are outlined. Triage is described in the context of public health emergencies and disaster settings, and the main ethical values at stake in triage are discussed. Possible conflicts between competing values are outlined. Special attention is given to p...
journal_title:Internal and emergency medicine
pub_type: 杂志文章,评审
doi:10.1007/s11739-010-0362-0
更新日期:2010-04-01 00:00:00