Abstract:
:Different mechanisms have been hypothesized to explain the increase in prevalence and severity of periodontitis in older adults, including shifts in the periodontal microbiota. However, the actual impact of aging on the composition of subgingival biofilms remains unclear. In the present article, we provide an overview of the composition of the subgingival biofilm in older adults and the potential effects of age on the oral microbiome. In particular, this review covers the following topics: (i) the oral microbiota of an aging mouth; (ii) the effects of age and time on the human oral microbiome; (iii) the potential impact of inflammaging and immunosenescence in the host-oral microbiota interactions; and (iv) the relationship of the aging oral microbiota and Alzheimer's disease. Finally, we present analyses of data compiled from large clinical studies that evaluated the subgingival microbiota of periodontally healthy subjects and patients with periodontitis from a wide age spectrum (20-83 years of age).
journal_name
Periodontol 2000journal_title
Periodontology 2000authors
Feres M,Teles F,Teles R,Figueiredo LC,Faveri Mdoi
10.1111/prd.12136subject
Has Abstractpub_date
2016-10-01 00:00:00pages
30-53issue
1eissn
0906-6713issn
1600-0757journal_volume
72pub_type
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journal_title:Periodontology 2000
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journal_title:Periodontology 2000
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journal_title:Periodontology 2000
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12314
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:2016-02-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:2020-10-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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journal_title:Periodontology 2000
pub_type: 杂志文章
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:2021-02-01 00:00:00
abstract::The periodontium is a very dynamic organ that responds rapidly to mechanical and chemical stimuli. It is very complex in that it is composed of two hard tissues (cementum and bone) and two soft connective tissues (periodontal ligament and gingiva). Together these tissues are defined by the molecules expressed by the r...
journal_title:Periodontology 2000
pub_type: 杂志文章
doi:10.1111/prd.12037
更新日期:2013-10-01 00:00:00
abstract::Periodontitis is an infectious/inflammatory disease characterized by the loss of periodontal ligament and alveolar bone. Herpesviruses are frequent inhabitants of periodontitis lesions, and the periodontopathogenicity of these viruses is the topic of this review. In 26 recent studies from 15 countries, subgingival cyt...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:2015-10-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:2014-10-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:2019-06-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12048
更新日期:2015-06-01 00:00:00
abstract::This chapter affirms that drugs and medicaments may have a profound effect on the periodontal structures. In some instances, such as drug-induced melanosis, the effect may be insignificant to the health of the patient. In other circumstances, drug-induced disorders may initiate painful, destructive disease processes t...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:1998-10-01 00:00:00
abstract::We have compiled, in this Periodontology 2000 review, all Latin American literature on experimental and clinical studies of periodontal plastic procedures. The body of literature on this subject has led to a discussion of the features and treatment outcomes of root-coverage procedures. Over time, knowledge on periodon...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12247
更新日期:2019-02-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12095
更新日期:2015-10-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:2021-02-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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journal_title:Periodontology 2000
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journal_title:Periodontology 2000
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更新日期:2016-02-01 00:00:00
abstract::Maxillary sinus augmentation is the most predictable of the pre-prosthetic surgical procedures. There are, however, known and well-documented complications that can and do occur. The most common are the intraoperative complications of sinus membrane perforation and bleeding, and the postoperative complications of sinu...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12286
更新日期:2019-10-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
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更新日期:2019-10-01 00:00:00
abstract::This review provides an update on genome-wide association studies in periodontitis. Studies in populations with European ancestry have dominated the landscape of periodontitis genetics studies but, increasingly, studies in Asian populations are being reported. The review also summarizes evidence for suggested associat...
journal_title:Periodontology 2000
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更新日期:2018-10-01 00:00:00
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journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1034/j.1600-0757.2000.2240112.x
更新日期:2000-10-01 00:00:00
abstract::Treatment of periodontitis aims at preventing further disease progression with the intentions to reduce the risk of tooth loss, minimize symptoms and perception of the disease, possibly restore lost periodontal tissue and provide information on maintaining a healthy periodontium. Therapeutic intervention includes intr...
journal_title:Periodontology 2000
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doi:10.1111/prd.12201
更新日期:2017-10-01 00:00:00
abstract::An extensive body of experimental and clinical evidence documents the negative impact of chronic psychological stress and depression on the immune system and health. Chronic stress and depression can result in general dysregulation of the immune system, of both cellular and humoral pathways, which may contribute to pa...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12036
更新日期:2014-02-01 00:00:00
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journal_title:Periodontology 2000
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更新日期:2020-06-01 00:00:00