Abstract:
:Oral mucosal diseases encompass a diverse array of conditions and disorders arising from malignant, potentially malignant, and nonneoplastic processes. Considerable attention has been paid to the former in recent years, much less to the wide range of nonneoplastic disease processes, which constitute a sizeable proportion of the oral disease burden globally. Many nonneoplastic disease processes of the oral mucosa significantly affect the patient's quality of life. Fortunately, timely identification and intervention can reduce the associated morbidity and, sometimes, mortality. As such, it is of utmost importance that dentists are familiar with early identification and management of this wide range of oral mucosal diseases. This volume of Periodontology 2000 provides a comprehensive contemporary review of such diseases and disorders through 15 chapters. We cover all relevant disease categories: developmental anomalies, infections, white and red lesions, vesiculo-bullous diseases, oral dermatoses, oral ulcerative conditions, dysplastic lesions, and mucosal diseases as manifestations of systemic disease or oral lesions as a part of systemic diseases. Each chapter discusses epidemiology, etiopathogenesis, clinical features, diagnosis, and management. Controversies and many significant gaps in knowledge are exposed, with suggestions for research to address limitations in current understandings. We take a look at the 2017 classification of the periodontal diseases and discuss the importance of close liaison between the specialties of oral medicine and of periodontology in the management of the many oral diseases, apart from the common forms primarily related to oral biofilm, affecting the gingivae and other parts of the periodontium.
journal_name
Periodontol 2000journal_title
Periodontology 2000authors
Ariyawardana A,Johnson NWdoi
10.1111/prd.12272subject
Has Abstractpub_date
2019-06-01 00:00:00pages
7-11issue
1eissn
0906-6713issn
1600-0757journal_volume
80pub_type
杂志文章,评审abstract::Dentists need to make daily decisions regarding patient care, and these decisions should essentially be scientifically sound. Evidence-based dentistry is meant to empower clinicians to provide the most contemporary treatment. The benefits of applying the evidence-based method in clinical practice include application o...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0757.2011.00437.x
更新日期:2012-06-01 00:00:00
abstract::Severe periodontitis is defined by extensive loss of the tooth attachment apparatus. It is the sixth most common human disease and is estimated to affect 11.2% of the global adult population, hence representing a significant healthcare, social, and economic burden. Since the 1990s, multiple epidemiologic, experimental...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12344
更新日期:2020-06-01 00:00:00
abstract::Periodontitis is a complex infectious disease that affects low-income individuals disproportionately. Periodontitis is associated with specific bacterial species and herpesviruses, and successful prevention and treatment of the disease is contingent upon effective control of these pathogens. This article presents an e...
journal_title:Periodontology 2000
pub_type: 杂志文章
doi:10.1111/j.1600-0757.2011.00429.x
更新日期:2012-10-01 00:00:00
abstract::The most important development in the epidemiology of periodontitis in the USA during the last decade is the result of improvements in survey methodologies and statistical modeling of periodontitis in adults. Most of these advancements have occurred as the direct outcome of work by the joint initiative known as the Pe...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12323
更新日期:2020-02-01 00:00:00
abstract::We have compiled, in this Periodontology 2000 review, all Latin American literature on experimental and clinical studies of periodontal plastic procedures. The body of literature on this subject has led to a discussion of the features and treatment outcomes of root-coverage procedures. Over time, knowledge on periodon...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12247
更新日期:2019-02-01 00:00:00
abstract::Translation of experimental data to the clinical setting requires the safety and efficacy of such data to be confirmed in animal systems before application in humans. In dental research, the animal species used is dependent largely on the research question or on the disease model. Periodontal disease and, by analogy, ...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12052
更新日期:2015-06-01 00:00:00
abstract::There is increasing public interest in natural or herbal-based healthcare products. This trend is not only visible in supermarkets and dental practices, but also in the scientific world. An improving number of clinical trials are being conducted to validate the claims made about these products in regards to periodonta...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12339
更新日期:2020-10-01 00:00:00
abstract::The primary goal of periodontal therapy is to produce an environment that is conducive to oral health. This is achieved by eliminating the subgingival infection and implementing supragingival plaque control measures designed to prevent the re-colonization of the sulcus. Local etiologic factors, as described above, my ...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1046/j.0906-6713.2003.003429.x
更新日期:2004-01-01 00:00:00
abstract::Surgical procedures of the oral cavity can be performed by a number of dental specialists and clinicians. Because of the limited number of surgical procedures that can be performed inside the oral cavity, the boundaries between specialties may become indistinct and lead to confusion for general dentists in terms of pa...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12196
更新日期:2017-06-01 00:00:00
abstract::In the 1960s and 1970s, implant-supported prostheses based on subperiosteal or blade implants had a poor reputation because of questionable clinical outcomes and lack of scientific documentation. The change to a scientifically sound discipline was initiated by the two scientific pioneers of modern implant dentistry, P...
journal_title:Periodontology 2000
pub_type: 历史文章,杂志文章,评审
doi:10.1111/prd.12185
更新日期:2017-02-01 00:00:00
abstract::A number of systemic disorders increase a patient's susceptibility to destructive periodontitis and have impacts on periodontal disease progression and severity. The underlying factors are usually genetic and are mainly related to alterations in the immune response and in certain endocrine functions, leading to variou...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12015
更新日期:2014-06-01 00:00:00
abstract::Studies ranging from preclinical animal models to human clinical trials support the basic hypothesis that the inhibition of local arachidonic acid metabolites with nonsteroidal anti-inflammatory drugs slows periodontal disease progression. Data on modulation of other host mediators such as cytokines and NO remain rest...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1034/j.1600-0757.2000.2240112.x
更新日期:2000-10-01 00:00:00
abstract::Cardiovascular diseases still account for the majority of deaths worldwide, although significant improvements in survival, after being affected by cardiovascular disease, have been achieved in the last decades. Periodontal diseases are also a common global burden. Several studies have shown a link between cardiovascul...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12302
更新日期:2020-06-01 00:00:00
abstract::For computer-guided surgery a static surgical guide is used that transfers the virtual implant position from computerized tomographic data to the surgical site. These guides are produced by computer-aided design/computer-assisted manufacture technology, such as stereolithography, or manually in a dental laboratory (us...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12056
更新日期:2014-10-01 00:00:00
abstract::This review has highlighted the importance of standardizing future investigations to enable more meaningful interstudy comparisons to be made. This report also makes recommendations for factors that should be considered and incorporated into future investigations, both in vitro and in vivo, in order to achieve more st...
journal_title:Periodontology 2000
pub_type: 历史文章,杂志文章,评审
doi:10.1111/j.1600-0757.2009.00300.x
更新日期:2009-01-01 00:00:00
abstract::An extensive body of experimental and clinical evidence documents the negative impact of chronic psychological stress and depression on the immune system and health. Chronic stress and depression can result in general dysregulation of the immune system, of both cellular and humoral pathways, which may contribute to pa...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12036
更新日期:2014-02-01 00:00:00
abstract::Maxillary sinus augmentation is the most predictable of the pre-prosthetic surgical procedures. There are, however, known and well-documented complications that can and do occur. The most common are the intraoperative complications of sinus membrane perforation and bleeding, and the postoperative complications of sinu...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12286
更新日期:2019-10-01 00:00:00
abstract::This paper is aimed to present a biomaterials perspective in implant therapy that fosters improved bone response and long-term biomechanical competence from surgical instrumentation to final prosthetic rehabilitation. Strategies to develop implant surface texturing will be presented and their role as an ad hoc treatme...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12288
更新日期:2019-10-01 00:00:00
abstract::This chapter affirms that drugs and medicaments may have a profound effect on the periodontal structures. In some instances, such as drug-induced melanosis, the effect may be insignificant to the health of the patient. In other circumstances, drug-induced disorders may initiate painful, destructive disease processes t...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0757.1998.tb00136.x
更新日期:1998-10-01 00:00:00
abstract::The zygoma implant has been an effective option in the management of the atrophic edentulous maxilla as well as for maxillectomy defects. Brånemark introduced the zygoma implant not only as a solution to obtain posterior maxillary anchorage but also to expedite the rehabilitation process. The zygoma implant is a thera...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12038
更新日期:2014-10-01 00:00:00
abstract::Despite the fact that several clinical studies have shown additional benefits when certain systemic antibiotics are used as adjuncts to periodontal treatment, clear guidelines for the use of these agents in the clinical practice are not yet available. Basic questions concerning the use of systemic antibiotics to treat...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12075
更新日期:2015-02-01 00:00:00
abstract::Numerous biological and cultural factors influence the microbial communities (microbiota) that inhabit the human mouth, including diet, environment, hygiene, physiology, health status, genetics, and lifestyle. As oral microbiota can underpin oral and systemic diseases, tracing the evolutionary history of oral microbio...
journal_title:Periodontology 2000
pub_type: 杂志文章
doi:10.1111/prd.12353
更新日期:2021-02-01 00:00:00
abstract::Recall sessions are an integral part of supportive periodontal therapy. The aim of the current article is to review the existing evidence to support if and to what extent a predefined frequency of periodontal recall sessions ensures periodontal health and stability. Factors that potentially affect the time interval fo...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12340
更新日期:2020-10-01 00:00:00
abstract::The discovery of neutrophil extracellular traps in 2004 opened a fascinating new chapter in immune-mediated microbial killing. Brinkman et al. demonstrated that neutrophils, when catastrophically stimulated, undergo a novel form of programmed cell death (neutrophil extracellular trap formation) whereby they decondense...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12025
更新日期:2013-10-01 00:00:00
abstract::Two dominant factors dictate which ingredients are used in formulating toothpaste and mouthwashes. The major one is the type of active ingredient chosen, especially cationic active ingredients such as chlorhexidine; the other factor is the needs of the consumer. Apart from gum health benefits, the consumer expects to ...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0757.1997.tb00102.x
更新日期:1997-10-01 00:00:00
abstract::Treatment of periodontitis aims at preventing further disease progression with the intentions to reduce the risk of tooth loss, minimize symptoms and perception of the disease, possibly restore lost periodontal tissue and provide information on maintaining a healthy periodontium. Therapeutic intervention includes intr...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12201
更新日期:2017-10-01 00:00:00
abstract::This paper focuses on plaque control and the management of gingivitis in adults and summarizes the evidence of commercially available dentifrices as gathered from existing systematic reviews. Three internet sources were used to search for appropriate papers (up to and including February 2017). The search strategy was ...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12257
更新日期:2019-02-01 00:00:00
abstract::MicroRNAs (miRNAs) are a family of small, noncoding RNA molecules that negatively regulate protein expression either by inhibiting initiation of the translation of mRNA or by inducing the degradation of mRNA molecules. Accumulating evidence suggests that miRNA-mediated repression of protein expression is of paramount ...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12095
更新日期:2015-10-01 00:00:00
abstract::The definition of osteoporosis has evolved beyond low bone mineral density to include impaired bone morphology and matrix properties. As such, the subsequent bone density insufficiencies extend beyond the skeletal risks of fracture and have implications for oral health management patients. As our population ages there...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0757.2011.00400.x
更新日期:2013-02-01 00:00:00
abstract::Evidence indicates that periodontal regeneration is an efficacious and predictable procedure for the treatment of isolated and multiple intrabony defects. Meta-analyses from systematic reviews indicate an added benefit, in terms of clinical attachment level gain, when demineralized freeze-dried bone allograft, barrier...
journal_title:Periodontology 2000
pub_type: 杂志文章,评审
doi:10.1111/prd.12048
更新日期:2015-06-01 00:00:00