Abstract:
:Acute rejection (AR) remains the biggest challenge during the first year after heart transplantation despite advances in immunosuppressive therapy. The early detection and curbing of AR are crucial to the survival of transplant recipients. However, as the criterion standard for AR, endomyocardial biopsy has several limitations because of its inherent invasiveness and morbidity. Traditional imaging techniques, such as echocardiography and cardiac magnetic resonance imaging, are of certain value for AR, but their diagnostic criteria and accuracy remain in question. Molecular imaging sheds new light on AR diagnosis because it can provide information about gene expression and the location of molecules and cells. This article reviews the latest research and applications of several typical modalities of molecular imaging used in AR and discusses their advantages and disadvantages.
journal_name
Transplantationjournal_title
Transplantationauthors
Chen Y,Zhang L,Liu J,Zhang P,Chen X,Xie Mdoi
10.1097/TP.0000000000001780subject
Has Abstractpub_date
2017-09-01 00:00:00pages
1977-1986issue
9eissn
0041-1337issn
1534-6080journal_volume
101pub_type
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