Section 8. Management of portal venous complications in pediatric living donor liver transplantation.

Abstract:

:Portal vein (PV) complications after living donor liver transplant (LDLT) have been a major concern in pediatric liver transplantation. The incidence of PV complications is more in pediatric (0%-33%) than in adult recipients. Early diagnosis and treatment of PV complications may ensure optimal graft function and good recipient survival. Small preoperation PV size (<4 mm) and slow portal flow (<10 cm/s) combined with lower hepatic artery resistance index (<0.65) are strong warning signs that may predict the development of post LDLT PV complications. Portal vein angioplasty/stenting is conventionally performed through the percutaneous transhepatic approach; however, this can also be performed through transjugular, trans-splenic, and intraoperative approaches. Depending on the situation, using optimal method is the key point to minimize complication (5%) and gain high success rate (80%). PV occlusion of greater than 1 year with cavernous transformation seems to be a factor causing technical failure. Good patency rate (100%) with self-expandable metallic stents was noted in long-term follow-up. In conclusion, PV stent placement is an effective, long-term treatment modality to manage PV complications after pediatric LDLT. Early diagnosis and treatment are essential to maximize the use of stent placement and achieve good success rates.

journal_name

Transplantation

journal_title

Transplantation

authors

Cheng YF,Ou HY,Yu CY,Tsang LL,Huang TL,Chen TY,Concejero A,Wang CC,Wang SH,Lin TS,Liu YW,Yang CH,Yong CC,Chiu KW,Jawan B,Eng HL,Chen CL

doi

10.1097/01.tp.0000446272.05687.ce

subject

Has Abstract

pub_date

2014-04-27 00:00:00

pages

S32-4

eissn

0041-1337

issn

1534-6080

pii

00007890-201404271-00011

journal_volume

97 Suppl 8

pub_type

杂志文章
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    authors: Smit JA,Drielsma RF,Myburgh JA,Laupacis A,Stiller CR

    更新日期:1983-08-01 00:00:00

  • Gastrointestinal Endoscopy Is Safe in Patients Before and After Lung or Heart Transplantation.

    abstract:BACKGROUND:Gastrointestinal complications are common in patients after lung and heart transplantation. Endoscopy is a standard method for the assessment of gastrointestinal morbidities. The aim of this study was to analyze the number and type of complications during endoscopic procedures in patients before and after lu...

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    pub_type: 杂志文章

    doi:10.1097/TP.0000000000000517

    authors: Lenzen H,Cieplik N,Elkharsawi AR,Negm AA,Avsar M,Bara CL,Gottlieb J,Manns MP,Lankisch TO

    更新日期:2015-07-01 00:00:00

  • Logistics and transplant coordination activity in the GRAGIL Swiss-French multicenter network of islet transplantation.

    abstract:BACKGROUND:Since the Edmonton trial in 2000, increasing numbers of transplant centers have been implementing islet transplantation programs. Some institutions have elected to associate in multicenter networks, such as the Swiss-French GRAGIL (Groupe Rhin-Rhône-Alpes-Genève pour la Transplantation d'Ilots de Langerhans)...

    journal_title:Transplantation

    pub_type: 杂志文章

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    更新日期:2005-05-15 00:00:00

  • Flow cytometry cross-match: a method for predicting graft rejection.

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    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199702270-00012

    authors: Utzig MJ,Blümke M,Wolff-Vorbeck G,Lang H,Kirste G

    更新日期:1997-02-27 00:00:00

  • Prolactin supplementation to culture medium improves beta-cell survival.

    abstract:OBJECTIVES:Recent studies demonstrated that prolactin (PRL) has beneficial effects on beta cells for islet transplantation. We examined the effect of human recombinant PRL (rhPRL) supplementation to the culture media to determine its potential use in the context of clinical islet transplantation. MATERIALS AND METHODS...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e3181d98af1

    authors: Yamamoto T,Mita A,Ricordi C,Messinger S,Miki A,Sakuma Y,Timoneri F,Barker S,Fornoni A,Molano RD,Inverardi L,Pileggi A,Ichii H

    更新日期:2010-06-15 00:00:00

  • Serum tumor markers after renal transplantation.

    abstract::The overall incidence of malignancy in renal transplant recipients is 100-fold higher compared with age matched controls. Routine clinical evaluation therefore often includes the determination of serum tumor markers AFP, CA19-9, CEA, CA125, CA15-3, PSA, and calcitonin. We evaluated the specificity and the sensitivity ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199611270-00021

    authors: Oberbauer R,Banyai S,Schmidt A,Kornek G,Scheithauer W,Mayer G

    更新日期:1996-11-27 00:00:00

  • Ten-year results of a randomized trial comparing tacrolimus versus cyclosporine a in combination with mycophenolate mofetil after heart transplantation.

    abstract:BACKGROUND:Long-term results of prospective randomized trials comparing triple immunosuppressive strategies combining tacrolimus (TAC) or cyclosporine A (CsA) with mycophenolate mofetil (MMF) and steroids after heart transplantation (HTX) are rarely published. Therefore, we collected long-term follow-up data of an inte...

    journal_title:Transplantation

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/TP.0b013e318277e378

    authors: Guethoff S,Meiser BM,Groetzner J,Eifert S,Grinninger C,Ueberfuhr P,Reichart B,Hagl C,Kaczmarek I

    更新日期:2013-02-27 00:00:00

  • Targeted Complement Inhibition Protects Vascularized Composite Allografts From Acute Graft Injury and Prolongs Graft Survival When Combined With Subtherapeutic Cyclosporine A Therapy.

    abstract:BACKGROUND:Recipients of vascularized composite allografts require aggressive and lifelong immunosuppression, and because the surgery is usually performed in nonlife-threatening situations, the development of strategies to minimize immunosuppression is especially pertinent for this procedure. We investigated how comple...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000001625

    authors: Zhu P,Bailey SR,Lei B,Paulos CM,Atkinson C,Tomlinson S

    更新日期:2017-04-01 00:00:00

  • Kidney transplantation from small pediatric donors: does recipient body mass index matter?

    abstract:BACKGROUND:The influence of recipient body mass index (BMI) on pediatric-donor kidney transplant outcomes is unclear. We aimed to determine graft survival and functional outcomes of pediatric-donor kidneys compared with adult kidneys stratified by recipient BMI group. METHODS:Scientific Registry of Transplant Recipien...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e318241d57d

    authors: Kayler LK,Zendejas I,Gregg A,Wen X

    更新日期:2012-02-27 00:00:00

  • Induction of delayed hypersensitivity to alloantigens coinjected with Langerhans cells into the anterior chamber of the eye. Abrogation of anterior chamber-associated immune deviation.

    abstract::Inoculation of P815 tumor cells (DBA/2 origin) into the anterior chamber of eyes of BALB/c mice normally produces anterior chamber-associated immune deviation (ACAID) whereby delayed hypersensitivity (DH) responses to the minor H alloantigens of the tumor cells are suppressed. Based on our previous work showing an ass...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-198903000-00024

    authors: Williamson JS,Streilein JW

    更新日期:1989-03-01 00:00:00

  • Possible involvement of the central nervous system in graft rejection.

    abstract::Electrolytic lesions were produced in the tuberal hypothalamus and amygdala of male Fischer and female BNLF1 rats, and in male Fischer and female BNLF1 rats that had received antecedent hypophysectomies. Skin grafts from Lewis rats survived less well on tuberal-lesioned male Fischer rats than similar grafts on sham-op...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-197904000-00002

    authors: Dann JA,Wachtel SS,Rubin AL

    更新日期:1979-04-01 00:00:00

  • Decrease in endothelial cell-dependent protein C activation induced by thrombomodulin by treatment with cyclosporine.

    abstract::The use of cyclosporine has been associated with an increased incidence of thrombosis and endothelial cell perturbation. To explore possible mechanisms involved, we examined the effects of CSA on the activation of protein C by thrombomodulin. Cultured bovine aortic endothelial cell monolayers were incubated for 24 hr ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199103000-00030

    authors: Garcia-Maldonado M,Kaufman CE,Comp PC

    更新日期:1991-03-01 00:00:00

  • Major histocompatibility complex class I peptide-pulsed host dendritic cells induce antigen-specific acquired thymic tolerance to islet cells.

    abstract:BACKGROUND:As T-cell receptor-major histocompatibility complex (MHC) class I/self peptide interaction regulates T-cell development in the thymus, we reasoned that presentation of peptides by self dendritic cells (DC) to developing T cells in the thymus might induce acquired thymic tolerance. This hypothesis is based on...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-200001270-00005

    authors: Ali A,Garrovillo M,Jin MX,Hardy MA,Oluwole SF

    更新日期:2000-01-27 00:00:00

  • Bone mineral density changes within six months of renal transplantation.

    abstract:BACKGROUND:The effective use of new steroid-sparing immunosuppressive regimens may lower cumulative glucocorticoid use among renal transplant recipients. However, it is unknown what effect this therapeutic trend has had on bone disease. METHODS:Unselected newly transplanted inpatients (n=45) were identified and compre...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-200301150-00009

    authors: Mikuls TR,Julian BA,Bartolucci A,Saag KG

    更新日期:2003-01-15 00:00:00

  • Skin-autofluorescence is an independent predictor of graft loss in renal transplant recipients.

    abstract:BACKGROUND:Skin-autofluorescence (skin-AF) noninvasively measures the tissue accumulation of advanced glycation end products (AGEs). AGEs are nephrotoxic and potential effectors of cardiovascular mortality. We investigated whether skin-AF predicted graft loss after kidney transplantation. METHODS:A total of 302 renal ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e31819d3173

    authors: Hartog JW,Gross S,Oterdoom LH,van Ree RM,de Vries AP,Smit AJ,Schouten JP,Nawroth PP,Gans RO,van Son WJ,Bierhaus A,Bakker SJ

    更新日期:2009-04-15 00:00:00

  • Beneficial effect of pentoxifylline on microvesicular steatotic livers submitted to a prolonged cold ischemia.

    abstract:BACKGROUND:The deleterious effect of steatosis on transplanted livers is mainly related to a microcirculation impairment. We investigated the effect of preservation duration on the recovery of isolated perfused rat steatotic livers and tested the effect of pentoxifylline (PTX), known to have a beneficial effect on hepa...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.TP.0000071846.35825.B1

    authors: Arnault I,Bao YM,Sebagh M,Anjo A,Dimicoli JL,Lemoine A,Delvart V,Adam R

    更新日期:2003-07-15 00:00:00

  • Increased QT dispersion in hemodialysis patients improve after renal transplantation: a prospective-controlled study.

    abstract::Increased QT dispersion (QTd), predicting patients with risk of malignant arrhythmia, have recently been reported in hemodialysis patients (HDp). In this prospective study, we aimed to investigate changes in QTd and signal averaged-ECG (SAECG) in HDp after transplantation. Twenty-seven HDp (M/F:18/9, mean age 30+/-8 y...

    journal_title:Transplantation

    pub_type: 临床试验,杂志文章

    doi:10.1097/00007890-200111150-00009

    authors: Yildiz A,Akkaya V,Tükek T,Sahin S,Sever MS,Bozfakioğlu S,Korkut F

    更新日期:2001-11-15 00:00:00

  • Cardiotrophin-1 Improves Kidney Preservation, Graft Function, and Survival in Transplanted Rats.

    abstract:BACKGROUND:Cold ischemia-reperfusion injury is unavoidable during organ transplantation, and prolonged preservation is associated with poorer function recovery. Cardiotrophin-1 (CT-1) is an IL-6 family cytokine with cytoprotective properties. This preclinical study in rats tested whether CT-1 mitigates cold renal ische...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000002313

    authors: García-Cenador B,Blanco-Gozalo V,López-Montañés D,Sanz Giménez-Rico JR,López-Novoa JM,López-Hernández FJ

    更新日期:2018-10-01 00:00:00

  • Blood citrulline level is an exclusionary marker for significant acute rejection after intestinal transplantation.

    abstract:BACKGROUND:Serum citrulline is a marker for acute cellular rejection (ACR) after intestinal transplantation; however, its clinical utility has not yet been established. The goal of this study was to determine clearcut serum levels beyond which the diagnosis of acute rejection could be supported or refuted, and predicto...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.tp.0000287186.04342.82

    authors: David AI,Selvaggi G,Ruiz P,Gaynor JJ,Tryphonopoulos P,Kleiner GI,Moon JI,Nishida S,Pappas PA,Conanan L,Weppler D,Esquenazi V,Levi DM,Kato T,Tzakis AG

    更新日期:2007-11-15 00:00:00

  • Assessment of efficacy and safety of FK778 in comparison with standard care in renal transplant recipients with untreated BK nephropathy.

    abstract:BACKGROUND:BK polyomavirus infection has been reported in 10% to 60% of renal transplant recipients with progression to BK nephropathy (BKN) occurring in 1% to 5% of patients. Graft loss occurs in up to 60% of renal transplant recipients with BKN. Because BK polyomavirus infection is believed, in part, to be a manifest...

    journal_title:Transplantation

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/TP.0b013e3181f2c94b

    authors: Guasch A,Roy-Chaudhury P,Woodle ES,Fitzsimmons W,Holman J,First MR,FK778 BK Nephropathy Study Group.

    更新日期:2010-10-27 00:00:00

  • Genes associated with progression and recurrence of hepatocellular carcinoma in hepatitis C patients waiting and undergoing liver transplantation: preliminary results.

    abstract:BACKGROUND:Liver transplantation (LT) represents a curative treatment for small hepatocellular carcinoma (HCC). Potentially curable higher-stage HCC patients are denied LT due to the lack of cancer markers that predict progression and recurrence. METHODS:Thirty-eight candidates for LT with hepatitis C virus (HCV) cirr...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.tp.0000258643.05294.0b

    authors: Mas VR,Fisher RA,Archer KJ,Yanek KC,Williams B,Dumur CI,Maluf DG

    更新日期:2007-04-15 00:00:00

  • Comparison of pulsatile perfusion and cold storage for paired kidney allografts.

    abstract::Use of pulsatile perfusion to optimize outcomes in deceased donor kidney transplantation remains controversial. This study is a retrospective analysis of all cadaveric renal allografts procured locally by our center over a 3-year period. Kidney pairs were identified in which one kidney underwent pulsatile perfusion an...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e318187b978

    authors: Shah AP,Milgrom DP,Mangus RS,Powelson JA,Goggins WC,Milgrom ML

    更新日期:2008-10-15 00:00:00

  • Overall Graft Loss Versus Death-Censored Graft Loss: Unmasking the Magnitude of Racial Disparities in Outcomes Among US Kidney Transplant Recipients.

    abstract:BACKGROUND:Black kidney transplant recipients experience disproportionately high rates of graft loss. This disparity has persisted for 40 years, and improvements may be impeded based on the current public reporting of overall graft loss by US regulatory organizations for transplantation. METHODS:Longitudinal cohort st...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000001119

    authors: Taber DJ,Gebregziabher M,Payne EH,Srinivas T,Baliga PK,Egede LE

    更新日期:2017-02-01 00:00:00

  • Plasma polymerase chain reaction for cytomegalovirus DNA after allogeneic marrow transplantation: comparison with polymerase chain reaction using peripheral blood leukocytes, pp65 antigenemia, and viral culture.

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    journal_title:Transplantation

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00007890-199707150-00020

    authors: Boeckh M,Gallez-Hawkins GM,Myerson D,Zaia JA,Bowden RA

    更新日期:1997-07-15 00:00:00

  • Safety of belatacept bridging immunosuppression in hepatitis C-positive liver transplant recipients with renal dysfunction.

    abstract:BACKGROUND:Perioperative renal dysfunction in liver transplant recipients complicates maintenance immunosuppressive therapy, particularly in patients with hepatitis C. Calcineurin inhibitors exacerbate renal dysfunction and mammalian target-of-rapamycin inhibitors are generally avoided because of perceived perioperativ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/01.TP.0000438635.44461.2e

    authors: LaMattina JC,Jason MP,Hanish SI,Ottmann SE,Klassen DK,Potosky D,Hutson WR,Barth RN

    更新日期:2014-01-27 00:00:00

  • Utilization of Donor Kidneys With Acute Kidney Injury in Pediatric Kidney Transplant Recipients.

    abstract:BACKGROUND:An elevated terminal creatinine is frequently used as a reason for organ refusal in pediatric kidney transplantation. There is increasing evidence that adults who receive kidneys from donors with moderate to severe acute kidney injury (AKI) have similar outcomes to recipients who receive kidneys from donors ...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0000000000002827

    authors: Solomon S,Hayde N

    更新日期:2020-03-01 00:00:00

  • Community-acquired respiratory viral infections in lung transplant recipients: a single season cohort study.

    abstract:BACKGROUND:The impact of community-acquired respiratory virus (CARV) infections on bronchiolitis obliterans syndrome (BOS) and outcome after lung transplantation (LTx) and diagnostic techniques were prospectively evaluated. METHODS:A single-center prospective cohort study was performed in LTx-outpatients between Octob...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/TP.0b013e3181a4857d

    authors: Gottlieb J,Schulz TF,Welte T,Fuehner T,Dierich M,Simon AR,Engelmann I

    更新日期:2009-05-27 00:00:00

  • Cellular immune responses of human cadaver donor bone marrow cells and their susceptibility to commonly used immunosuppressive drugs in transplantation.

    abstract:BACKGROUND:The cascade of immunological effects brought about by donor bone marrow cell (DBMC) infusions in human organ transplantation, especially in the context of continuous pharmacologic immunosuppression, is not fully understood. Yet, in inbred rodents and even primates, administration of specific bone marrow cell...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199804150-00015

    authors: Mathew JM,Carreno M,Zucker K,Fuller L,Kenyon N,Esquenazi V,Ricordi C,Tzakis AG,Miller J

    更新日期:1998-04-15 00:00:00

  • Comparison between duodenal button and duodenal segment in pancreas transplantation.

    abstract::Two technical modifications have been suggested for whole-pancreas transplantation with bladder drainage. The duodenal button technique (DB [Madison]) and the duodenal segment technique (DS [Iowa]) are the most commonly performed procedures (1,2). From December 1985 until May 1988 we performed 32 combined pancreas-kid...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-198901000-00026

    authors: D'Alessandro AM,Sollinger HW,Stratta RJ,Kalayoglu M,Pirsch JD,Belzer FO

    更新日期:1989-01-01 00:00:00

  • Pharmacokinetics of methylprednisolone and rejection episodes in kidney transplant patients.

    abstract::Rejection crises after kidney transplantation could be associated with individual variability of pharmacokinetic parameters of steroids. We therefore investigated the individual pharmacokinetics of methylprednisolone on day 2 (60 mg intravenously) and day 4 (60 mg per os) in 40 patients after kidney transplantation. M...

    journal_title:Transplantation

    pub_type: 杂志文章

    doi:10.1097/00007890-199508270-00005

    authors: Keller F,Hemmen T,Schöneshöfer M,Schwarz A,Offermann G

    更新日期:1995-08-27 00:00:00