Blood citrulline level is an exclusionary marker for significant acute rejection after intestinal transplantation.

abstract：:Dendritic-shaped cells (Thy-1+DC) characterized by the surface phenotype of Thy-1+, asialo GM1+, Ia- are reported to exist exclusively in mice. However, Thy-1+ dendritic cells were observed in the skin of normal athymic nude F344, euthymic F344, and WKAH rats. Their phenotypic markers were Thy-1+, asialo GM1+, Ia-, W3...

journal_title：Transplantation

authors： Ueda A,Ito M,Ishiguro N,Miura Y,Asai J,Miura T

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The use of anti-B-cell and T-cell immunosuppressive agents leads to only a few weeks' survival of mouse-to-rat cardiac xenografts. METHODS:BALB/c cardiac xenografts were transplanted to Lewis rats treated with cyclosporine (CsA) and/or cobra venom factor (CVF). RESULTS:CsA alone did not prolong xenograft s...

journal_title：Transplantation

authors： Koyamada N,Miyatake T,Candinas D,Mark W,Hechenleitner P,Hancock WW,Soares MP,Bach FH

更新日期：1998-05-15 00:00:00

abstract：:We studied the role of interleukin (IL)-8 during engraftment after hematopoietic stem cell transplantation. In 40 consecutive patients undergoing either allogeneic marrow (n=32) or autologous peripheral blood stem cell transplantation (n=8), IL-8 plasma levels were serially determined. Median IL-8 concentrations peake...

journal_title：Transplantation

authors： Schwabe M,Hartert AM,Bertz H,Finke J

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:Infectious complications occur in approximately 50% of cadaveric liver transplant (CDLT) recipients. Living-donor liver transplantation (LDLT) is an established alternative to shorten the waiting time. Currently, the incidence of pulmonary infections after LDLT and the microbiologic causes are unknown. In th...

journal_title：Transplantation

authors： Saner FH,Olde Damink SW,Pavlakovic G,van den Broek MA,Rath PM,Sotiropoulos GC,Radtke A,Canbay A,Paul A,Nadalin S,Malagó M,Broelsch CE

更新日期：2008-06-15 00:00:00

abstract：BACKGROUND:In a recent trial, targeted mild hypothermia in brain-dead organ donors significantly reduced the incidence of delayed graft function after kidney transplantation. This trial was stopped early for efficacy. Here, we report long-term graft survival for all organs along with donor critical care end points. ME...

journal_title：Transplantation

authors： Malinoski D,Patel MS,Axelrod DA,Broglio K,Lewis RJ,Groat T,Niemann CU

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Leflunomide is a novel immunosuppressive agent with promising activity for xenotransplantation. It is not clear yet which mechanisms of action of leflunomide are responsible for that. METHODS:In a hamster-to-C57BL/6 nude mouse heart transplantation model, a 2-week course of leflunomide was used after transp...

journal_title：Transplantation

authors： Yan Y,Verbeken E,Yu L,Rutgeerts O,Goebels J,Segers C,Lin Y,Waer M

更新日期：2005-01-27 00:00:00

abstract：:We have analyzed PBL from 7 children exposed to CsA in utero and 4 children exposed to AZA in utero. Expression of CD3, CD4, CD8, and CD20 were normal for both groups of children; however, significant differences were detected in the expression of CD45RA, CD45R0, and CD29. While CsA-exposed children had higher density...

journal_title：Transplantation

authors： Pilarski LM,Yacyshyn BR,Lazarovits AI

更新日期：1994-01-01 00:00:00

abstract：:We report two cases of Kaposi's sarcoma (KS) after orthotopic liver transplantation for cirrhosis of the liver related to hepatitis C virus. Both cases were Saudi-born Arabs who were negative for human immunodeficiency virus; one patient was receiving FK506 plus prednisolone, and the other patient was receiving FK506....

journal_title：Transplantation

authors： Rezeig MA,Fashir BM,Hainau B,Al Ashgar HI

更新日期：1997-05-27 00:00:00

abstract：BACKGROUND:Mixed allogeneic hematopoietic chimerism has previously been reliably achieved and shown to induce tolerance to fully MHC-mismatched allografts in mice and monkeys. However, the establishment of hematopoietic chimerism has been difficult to achieve in the discordant pig-to-primate xenogeneic model. METHODS:...

journal_title：Transplantation

authors： Sablinski T,Emery DW,Monroy R,Hawley RJ,Xu Y,Gianello P,Lorf T,Kozlowski T,Bailin M,Cooper DK,Cosimi AB,Sachs DH

更新日期：1999-04-15 00:00:00

abstract：BACKGROUND:The impact of the age of the donor on the outcome of living related liver transplantation is yet to be clarified. METHODS:During October 14, 1996 and December 20, 1999, 34 living related liver transplantations were performed. Of these, 26 cases were performed using the extended left lobe graft, which were c...

journal_title：Transplantation

authors： Ikegami T,Nishizaki T,Yanaga K,Shimada M,Kishikawa K,Nomoto K,Uchiyama H,Sugimachi K

更新日期：2000-12-27 00:00:00

abstract：:Unrelated cord blood (UCB) hematopoietic stem cells were serially transplanted into two human leukocyte antigen (HLA)-identical siblings with T cell, B cell, natural killer cell severe combined immunodeficiency. Brother A received a 4/6-matched, HLA DRbeta1-identical but class I-disparate UCB graft after myeloablative...

journal_title：Transplantation

authors： Goebel WS,Nelson RP Jr,Brahmi Z,Gowan DJ,Towell PJ,Robertson KA,Haut PR

更新日期：2006-06-15 00:00:00

abstract：:Subsets of T cells have been identified by the expression of different isoforms of CD45. Some T cells expressing CD45RA (gp220) have been characterized as "naive" in their response to antigens including alloantigens, whereas T cells expressing CD45RO (gp180) have been characterized as "memory" T cells. To examine the ...

journal_title：Transplantation

authors： Ibrahim S,Dawson DV,Sanfilippo F

更新日期：1995-03-15 00:00:00

abstract：:The response to IL-2 and IL-4 of several functionally defined lymphoid cell types was assessed at the individual responding cell level in limiting dilution experiments in which exogenous IL-2 or IL-4 was used to promote cellular activation and expansion. Splenic precursors that give rise to alloreactive CTL in LDA sup...

journal_title：Transplantation

authors： Widmer MB,Voice RF,Conlon PJ,Grabstein KH

更新日期：1990-04-01 00:00:00

abstract：:The influence of methotrexate on the development of immunity to the line 10 hepatoma was studied in guinea pigs. Chronic methotrexate treatment had no apparent effect on the ability of immune guinea pigs to suppress the growth of inoculated tumor cells. In contrast, the same methotrexate regimen inhibited the developm...

journal_title：Transplantation

authors： Shu S,Fonseca LS,Hunter JT,Rapp HJ

更新日期：1983-01-01 00:00:00

abstract：:The nature of cell-mediated immunity in the American cockroach (Periplaneta americana) was studied by observing the events involved in graft reactivity. Adult roaches received integumentary xenografts from Blaberus giganteus, as well as control autografts. Grafts were scored histologically by counting the number of nu...

journal_title：Transplantation

authors： George JF,Karp RD,Rheins LA

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Previous studies have indicated that patients on maintenance hemodialysis have worse survival compared with kidney transplant (KTx) recipients. However, none of these studies have compared mortality of the US patients using alternative dialysis modalities such as home hemodialysis (HHD) with KTx recipients. ...

journal_title：Transplantation

authors： Molnar MZ,Ravel V,Streja E,Kovesdy CP,Mehrotra R,Kalantar-Zadeh K

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Combined lung and liver transplantation (Lu-LTx) is a therapeutic option for selected patients with coexisting lung and liver disease. For several reasons, Lu-LTx is performed in few centers and information about the technical issues, posttransplant management and long-term outcomes associated with this proc...

journal_title：Transplantation

authors： Grannas G,Neipp M,Hoeper MM,Gottlieb J,Lück R,Becker T,Simon A,Strassburg CP,Manns MP,Welte T,Haverich A,Klempnauer J,Nashan B,Strueber M

更新日期：2008-02-27 00:00:00

abstract：:Histoincompatibility was analyzed to describe as precisely as possible the sequence of gross morphological events taking place during allograft rejection among closely related conspecifics from a natural population of the bisexual lizard Cnemidophorus tigris. Two types of rejection were noted, depending on whether the...

journal_title：Transplantation

authors： Cuellar O,Smart C

更新日期：1977-08-01 00:00:00

abstract：:Since the earliest days of transplantation, immunobiologists have sought means to prevent recognition and rejection of foreign tissue. The goal of these strategies is the retention of recipient immune function while selectively avoiding graft injury. Although considerable theoretical and technical problems remain, an ...

journal_title：Transplantation

authors： Lynch RJ,Platt JL

更新日期：2009-12-15 00:00:00

abstract：:Eight patients with chronic myeloid leukemia relapse after allogeneic BMT were treated with IFN-alpha and buffy coat transfusions (BC) of the bone marrow donor. The antileukemic effect of this treatment was directly demonstrated in 4 patients by the disappearance of Philadelphia chromosome-positive metaphases or the l...

journal_title：Transplantation

authors： Hertenstein B,Wiesneth M,Novotny J,Bunjes D,Stefanic M,Heinze B,Hübner G,Heimpel H,Arnold R

更新日期：1993-11-01 00:00:00

abstract：:The ability of the popliteal lymph node assay (PLNA) To detect host-versus-graft activity in response to H-Y antigens was investigated in the rat by using presensitized recipients. It was shown that significant popliteal lymph node (PLN) enlargement in response to H-Y-incompatible lymphocytes from syngeneic donors cou...

journal_title：Transplantation

authors： Markwick JR,Pegrum GD

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:The prevalence of renal posttransplantation amputation and its impact on allograft and patient survival have not been widely reported. METHODS:We used an incident cohort of patients who underwent renal transplantation between June 2004 and September 2009. Amputation data were obtained using Medicare institu...

journal_title：Transplantation

authors： Brar A,Jindal RM,Sumrani N,John D,Mondal Z,Tedla F,Salifu MO

更新日期：2013-05-27 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) infection is common in kidney transplantation and is known to affect long-term patient and graft survival, as is time in renal-replacement therapy (RRT). The aim of this study was to investigate HCV in relation to time in RRT and its impact on outcome after transplantation. METHODS:A...

journal_title：Transplantation

authors： Bruchfeld A,Wilczek H,Elinder CG

更新日期：2004-09-15 00:00:00

abstract：BACKGROUND:The influence of the preservation solution used for in situ perfusion of the donor and pancreas storage on islet isolation has received little attention. METHODS:In this prospective controlled trial, we compared the outcome of human islet isolation from pancreata perfused with University of Wisconsin (UW) s...

journal_title：Transplantation

authors： Hubert T,Gmyr V,Arnalsteen L,Jany T,Triponez F,Caiazzo R,Vandewalle B,Vantyghem MC,Kerr-Conte J,Pattou F

更新日期：2007-02-15 00:00:00

abstract：BACKGROUND:The role of CD20+ B cells in renal allograft rejection has been reappreciated. Importantly, recent studies suggest a relation between CD20+ B cell aggregates and poorer clinical outcome. In the present study, we attempted to confirm these early reports in a tightly controlled patient population and to differ...

journal_title：Transplantation

authors： Scheepstra C,Bemelman FJ,van der Loos C,Rowshani AT,van Donselaar-Van der Pant KA,Idu MM,ten Berge IJ,Florquin S

更新日期：2008-09-27 00:00:00

abstract：BACKGROUND:Composite tissue allotransplantation (CTA) is a recently introduced option for limb replacement and reconstruction of other nonreconstructible tissue defects. As with recipients of other allotransplants, CTA recipients can experience rejection episodes that are presumed to be mediated by immune mechanisms si...

journal_title：Transplantation

authors： Cendales LC,Kirk AD,Moresi JM,Ruiz P,Kleiner DE

更新日期：2005-12-27 00:00:00

abstract：:We have investigated the immunosuppressive effects of thalidomide (Thal) in a bone marrow transplant (BMT) model for graft-versus-host disease (GVHD). Lewis rats received RT1-incompatible marrow transplants from ACI rats after total-body irradiation. Twenty-two of twenty-three rats with established severe acute GVHD w...

journal_title：Transplantation

authors： Vogelsang GB,Hess AD,Gordon G,Santos GW

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Genetic variants of the renin-angiotensin system (RAS) have been implicated in the progression of native kidney diseases. A decreased long-term renal allograft function has also been associated with increased activity of RAS, which may be genetically determined. METHODS:The effect of the angiotensinogen (AG...

journal_title：Transplantation

authors： Nicod J,Richard A,Frey FJ,Ferrari P

更新日期：2002-03-27 00:00:00

abstract：:Israel's rates of organ donation have been one of the lowest among developed countries. An attempt to change this has led to the introduction of a pioneering new law, the Organ Transplant Act 2008, which came into effect in January 2010 and sets out principles underlying a new policy in relation to the allocation of o...

journal_title：Transplantation

authors： Quigley M,Wright L,Ravitsky V

更新日期：2012-05-27 00:00:00

abstract：:Forty-three human liver allograft biopsies and normal liver were directly analyzed for inflammatory and immunoregulatory cytokine gene expression by polymerase chain reaction (PCR). IL-5 gene expression was predominantly present in biopsies from liver allografts with histopathological evidence of acute rejection. IL-2...

journal_title：Transplantation

authors： Martinez OM,Krams SM,Sterneck M,Villanueva JC,Falco DA,Ferrell LD,Lake J,Roberts JP,Ascher NL

更新日期：1992-02-01 00:00:00