Abstract：
BACKGROUND:Neuroevolution comprises the use of evolutionary computation to define the architecture and/or to train artificial neural networks (ANNs). This strategy has been employed to investigate the behavior of rats in the elevated plus-maze, which is a widely used tool for studying anxiety in mice and rats. NEW METHOD:Here we propose a neuroevolutionary model, in which both the weights and the architecture of artificial neural networks (our virtual rats) are evolved by a genetic algorithm. COMPARISON WITH EXISTING METHOD(S):This model is an improvement of a previous model that involves the evolution of just the weights of the ANN by the genetic algorithm. In order to compare both models, we analyzed traditional measures of anxiety behavior, like the time spent and the number of entries in both open and closed arms of the maze. RESULTS:When compared to real rat data, our findings suggest that the results from the model introduced here are statistically better than those from other models in the literature. CONCLUSIONS:In this way, the neuroevolution of architecture is clearly important for the development of the virtual rats. Moreover, this technique allowed the comprehension of the importance of different sensory units and different number of hidden neurons (performing as memory) in the ANNs (virtual rats).
journal_name
J Neurosci Methodsjournal_title
Journal of neuroscience methodsauthors
Costa AA,Tinós Rdoi
10.1016/j.jneumeth.2016.06.010subject
Has Abstractpub_date
2016-09-01 00:00:00pages
102-110eissn
0165-0270issn
1872-678Xpii
S0165-0270(16)30131-5journal_volume
270pub_type
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