Abstract：
:Apicomplexan protist parasites utilize host sugars transported into the parasite by sugar transporter proteins for use as an energy source. We performed a phylum-wide phylogenetic analysis of the apicomplexan sugar transporter repertoire. Phylogenetic analyses revealed six major subfamilies of apicomplexan sugar transporters. Transporters in one subfamily have undergone expansions in Piroplasma species and Gregarina niphandrodes, while other subfamilies are highly divergent and contain genes found in only one or two species. Analyses of the divergent apicomplexan subfamilies revealed their presence in ciliates, indicating their alveolate ancestry and subsequent loss in chromerids and many apicomplexans.
journal_name
Int J Genomicsjournal_title
International journal of genomicsauthors
Mahmud O,Kissinger JCdoi
10.1155/2017/1707231subject
Has Abstractpub_date
2017-01-01 00:00:00pages
1707231eissn
2314-436Xissn
2314-4378journal_volume
2017pub_type
杂志文章abstract：:We characterized the male-specific region on the Y chromosome of rainbow trout, which contains both sdY (the sex-determining gene) and the male-specific genetic marker, OmyY1. Several clones containing the OmyY1 marker were screened from a BAC library from a YY clonal line and found to be part of an 800 kb BAC contig....
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2013/261730
更新日期：2013-01-01 00:00:00
abstract：:High throughput genomic assays empower us to study the entire human genome in short time with reasonable cost. Formalin fixed-paraffin-embedded (FFPE) tissue processing remains the most economical approach for longitudinal tissue specimen storage. Therefore, the ability to apply high throughput genomic applications to...
journal_title：International journal of genomics
pub_type： 杂志文章,评审
doi：10.1155/2017/1926304
更新日期：2017-01-01 00:00:00
abstract：:Rheumatoid arthritis (RA) is an autoimmune disease characterized by the presence of antibodies against cyclic citrullinated peptide (anti-CCP), a consequence of the breakdown of immune tolerance. The lymphoid tyrosine phosphatase (Lyp) protein has significant effects on maintenance of peripheral immune tolerance. Two ...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2017/8753498
更新日期：2017-01-01 00:00:00
abstract：:To better understand the molecular functions of the master stress-response regulator AtfA in Aspergillus nidulans, transcriptomic analyses of the atfA null mutant and the appropriate control strains exposed to menadione sodium bisulfite- (MSB-), t-butylhydroperoxide- and diamide-induced oxidative stresses were perform...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2017/6923849
更新日期：2017-01-01 00:00:00
abstract：Background:Nonalcoholic fatty liver disease (NAFLD) has become a leading cause of liver transplantation. Lingguizhugan decoction (LGZG), a classical Chinese herbal formula, has beneficial effects on NAFLD animal models. Our study examined the impact of LGZG on hepatic global transcriptome of high-fat-diet-induced NAFLD...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2017/2790864
更新日期：2017-01-01 00:00:00
abstract：:To explore heat response mechanisms of mircoRNAs (miRNAs) in rice post-meiosis panicle, microarray analysis was performed on RNA isolated from rice post-meiosis panicles which were treated at 40°C for 0 min, 10 min, 20 min, 60 min, and 2 h. By integrating paired differentially expressed (DE) miRNAs and mRNA expression...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2020/7582612
更新日期：2020-09-17 00:00:00
abstract：:Identifying differentially variable (DV) genomic probes is becoming a new approach to detect novel genomic risk factors for complex human diseases. The F test is the standard equal-variance test in statistics. For high-throughput genomic data, the probe-wise F test has been successfully used to detect biologically rel...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2018/6591634
更新日期：2018-07-12 00:00:00
abstract：:Drought is the main environmental factor impairing hemp growth and yield. In order to decipher the molecular responses of hemp to drought stress, transcriptome changes of drought-stressed hemp (DS1 and DS2), compared to well-watered control hemp (CK1 and CK2), were studied with RNA-Seq technology. RNA-Seq generated 9....
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2018/3057272
更新日期：2018-05-15 00:00:00
abstract：:miRNAs are a class of noncoding RNAs important in posttranscriptional repressors and involved in the regulation of almost every biological process by base paring with target genes through sequence in their seed regions. Genetic variations in the seed regions have vital effects on gene expression, phenotypic variation,...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2018/2456076
更新日期：2018-03-06 00:00:00
abstract：:Puberty is a transition period where a child transforms to an adult. Puberty can be affected by various genetic factors and environmental influences. In mammals, the regulation of puberty is enhanced by the hypothalamic-pituitary-gonadal axis (HPG axis). A number of genes such as GnRH, Kiss1, and GPR54 have been repor...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2020/1426761
更新日期：2020-05-22 00:00:00
abstract：:We screened bacteria that use E2 as its sole source of carbon and energy for growth and identified them as Rhodococcus, and we named them DSSKP-R-001. For a better understanding of the metabolic potential of the strain, whole genome sequencing of Rhodococcus DSSKP-R-001 and annotation of the functional genes were perf...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2018/3505428
更新日期：2018-10-28 00:00:00
abstract：:Kivircik sheep is an important local Turkish sheep according to its meat quality and milk productivity. The aim of this study was to analyze gene expression profiles of both prenatal and postnatal stages for the Kivircik sheep. Therefore, two different cDNA libraries, which were taken from the same Kivircik sheep mamm...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2017/9604762
更新日期：2017-01-01 00:00:00
abstract：:In recent years the human microbiome has become a growing area of research and it is becoming clear that the microbiome of humans plays an important role for human health. Extensive research is now going into cataloging and annotating the functional role of the human microbiome. The ability to explore and describe the...
journal_title：International journal of genomics
pub_type： 杂志文章,评审
doi：10.1155/2016/5304028
更新日期：2016-01-01 00:00:00
abstract：:Paeonia lactiflora is a herbaceous flower in the family Paeoniaceae with both hypocotyl and epicotyl dormant seeds. We used high-throughput transcriptome sequencing on two different developmental stages of P. lactiflora seeds to identify seed dormancy and germination-related genes. We performed de novo assembly and an...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2017/8027626
更新日期：2017-01-01 00:00:00
abstract：:Simple sequence repeats (SSRs) are among the most important markers for population analysis and have been widely used in plant genetic mapping and molecular breeding. Expressed sequence tag-SSR (EST-SSR) markers, located in the coding regions, are potentially more efficient for QTL mapping, gene targeting, and marker-...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2015/473028
更新日期：2015-01-01 00:00:00
abstract：Purpose:Next-generation sequencing (NGS) has become more accessible, leading to an increasing number of genetic studies of familial bradycardia being reported. However, most of the variants lack full evaluation. The relationship between genetic factors and bradycardia should be summarized and reevaluated. Methods:We s...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2020/2415850
更新日期：2020-02-25 00:00:00
abstract：:Determining protein-protein interaction (PPI) in biological systems is of considerable importance, and prediction of PPI has become a popular research area. Although different classifiers have been developed for PPI prediction, no single classifier seems to be able to predict PPI with high confidence. We postulated th...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2015/608042
更新日期：2015-01-01 00:00:00
abstract：:Severe gastroenteritis and foodborne illness caused by Noroviruses (NoVs) during the winter are a worldwide phenomenon. Vulnerable populations including young children and elderly and immunocompromised people often require hospitalization and may die. However, no efficient vaccine for NoVs exists because of their vari...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2013/456356
更新日期：2013-01-01 00:00:00
abstract：:Background and Objectives. Chronic obstructive pulmonary disease (COPD) is a complex disease characterized by airflow limitation. Although airway inflammation and oxidative stress are known to be important in the pathogenesis of COPD, the mechanism underlying airflow obstruction is not fully understood. Gene expressio...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2015/206937
更新日期：2015-01-01 00:00:00
abstract：:Cardiovascular disease is a leading cause of death in both humans and dogs. Dilated cardiomyopathy (DCM) accounts for a large number of these cases, reported to be the third most common form of cardiac disease in humans and the second most common in dogs. In human studies of DCM there are more than 50 genetic loci ass...
journal_title：International journal of genomics
pub_type： 杂志文章,评审
doi：10.1155/2015/204823
更新日期：2015-01-01 00:00:00
abstract：:Rice grain shape and nutritional quality traits have high economic value for commercial production of rice and largely determine the market price, besides influencing the global food demand for high-quality rice. In order to understand the genetic components of grain appearance traits in paddy, brown, and head rice, 1...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2019/3160275
更新日期：2019-02-25 00:00:00
abstract：:The HIV-1 virus (human immunodeficiency virus) affects 36.9 million people worldwide, with approximately 900000 deaths in 2017. The virus carrier can develop severe immunodeficiency since CD4+ T lymphocytes are the main target, leading to acquired immunodeficiency syndrome (AIDS). Despite advances in pharmacological t...
journal_title：International journal of genomics
pub_type： 杂志文章,评审
doi：10.1155/2019/8458263
更新日期：2019-08-21 00:00:00
abstract：:Auxin response factors (ARFs) have been reported to play vital roles during plant growth and development. In order to reveal specific functions related to vegetative organs in grasses, an in-depth study of the ARF gene family was carried out in switchgrass (Panicum virgatum L.), a warm-season C4 perennial grass that i...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2018/7658910
更新日期：2018-04-29 00:00:00
abstract：:The expression level of each gene is controlled by its regulatory regions, which determine the precise regulation in a tissue-specific manner, according to the developmental stage of the body and the necessity of a response to external stimuli. Nucleotide substitutions in regulatory gene regions may modify the affinit...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2015/260159
更新日期：2015-01-01 00:00:00
abstract：:The Gene Ontology (GO) provides a resource for consistent annotation of genes and gene products that is extensively used by numerous large public repositories. The GO is constructed of three subontologies describing the cellular component of action, molecular function, and overall biological process of a gene or gene ...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2013/594528
更新日期：2013-01-01 00:00:00
abstract：:Osteoporosis is a serious public health issue, which is mostly characterized by low bone mineral density (BMD). To search for additional genetic susceptibility loci underlying BMD variation, an effective strategy is to focus on testing of specific variants with high potential of functional effects. Single nucleotide p...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2018/6407257
更新日期：2018-08-07 00:00:00
abstract：:TSEN54 encodes a subunit of the tRNA-splicing endonuclease complex, which catalyzes the identification and cleavage of introns from precursor tRNAs. Previously, we identified an AluSx-derived alternative transcript in TSEN54 of cynomolgus monkey. Reverse transcription-polymerase chain reaction (RT-PCR) amplification a...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2016/1679574
更新日期：2016-01-01 00:00:00
abstract：:The purpose of this work was to study changes in the level of cell-free DNA (cfDNA) in the blood of young and old rats in the normal state and with induced benign prostatic hyperplasia (BPH). Male Wistar rats were divided into 4 groups-young (3 months), old (20 months), intact, or with testosterone-induced BPH. Groups...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2019/8173630
更新日期：2019-06-02 00:00:00
abstract：:In general, mutation frequencies are context-dependent: specific adjacent nucleotides may influence the probability to observe a specific type of mutation in a genome. Recently, several hypermutable motifs were identified in the human genome. Namely, there is an increased frequency of T>C mutations in the second posit...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2013/173616
更新日期：2013-01-01 00:00:00
abstract：:Insulin resistance has a central role in the pathogenesis of several metabolic diseases, including type 2 diabetes, obesity, glucose intolerance, metabolic syndrome, atherosclerosis, and cardiovascular diseases. Insulin resistance and related traits are likely to be caused by abnormalities in the genes encoding for pr...
journal_title：International journal of genomics
pub_type： 杂志文章
doi：10.1155/2013/376454
更新日期：2013-01-01 00:00:00
