Clustering Pattern and Functional Effect of SNPs in Human miRNA Seed Regions.

abstract：:The genera Actinobacillus, Haemophilus, and Pasteurella exhibit extensive polyphyletic branching in phylogenetic trees and do not represent coherent clusters of species. In this study, we have utilized molecular signatures identified through comparative genomic analyses in conjunction with genome based and multilocus ...

journal_title：International journal of genomics

authors： Naushad S,Adeolu M,Goel N,Khadka B,Al-Dahwi A,Gupta RS

更新日期：2015-01-01 00:00:00

abstract：:The Gene Ontology (GO) provides a resource for consistent annotation of genes and gene products that is extensively used by numerous large public repositories. The GO is constructed of three subontologies describing the cellular component of action, molecular function, and overall biological process of a gene or gene ...

journal_title：International journal of genomics

authors： Francis RW

更新日期：2013-01-01 00:00:00

abstract：:Paulownia witches' broom caused by phytoplasma infection affects the production of Paulownia trees worldwide. Emerging evidence showed that long noncoding RNAs (lncRNA) play a protagonist role in regulating the expression of genes in plants. So far, the identification of lncRNAs has been limited to a few model plant s...

journal_title：International journal of genomics

authors： Fan G,Cao Y,Wang Z

更新日期：2018-02-21 00:00:00

abstract：:Sweet sorghum (Sorghum bicolor) is one of the most important cereal crops in the world with colorful seeds. To study the diversity and cultivar-specificity of phytochemicals in sweet sorghum seeds, widely targeted metabolomics was used to analyze the metabolic profiles of the white, red, and purple seeds from three sw...

journal_title：International journal of genomics

authors： Zhou Y,Wang Z,Li Y,Li Z,Liu H,Zhou W

更新日期：2020-03-04 00:00:00

abstract：:Arabidopsis thaliana (L.) Heynh. is a model organism of plant molecular biology. More than 1,700 whole genome sequences have been sequenced, but no Korean isolate genomes have been sequenced thus far despite the fact that many A. thaliana isolated in Japan and China have been sequenced. To understand the genetic backg...

journal_title：International journal of genomics

authors： Park J,Xi H,Kim Y

更新日期：2020-09-05 00:00:00

abstract：:Severe gastroenteritis and foodborne illness caused by Noroviruses (NoVs) during the winter are a worldwide phenomenon. Vulnerable populations including young children and elderly and immunocompromised people often require hospitalization and may die. However, no efficient vaccine for NoVs exists because of their vari...

journal_title：International journal of genomics

authors： Huang CC,Tang CY

更新日期：2013-01-01 00:00:00

abstract：:The yellow color of inner leaves in Chinese cabbage depends on its lutein and carotene content. To identify responsible genes for yellow pigmentation in leaves, the transcriptome profiles of white (Kenshin) and yellow leaves (Wheessen) were examined using the Br300K oligomeric chip in Chinese cabbage. In yellow leaves...

journal_title：International journal of genomics

authors： Jung HJ,Manoharan RK,Park JI,Chung MY,Lee J,Lim YP,Hur Y,Nou IS

更新日期：2014-01-01 00:00:00

abstract：:Osteoporosis is a serious public health issue, which is mostly characterized by low bone mineral density (BMD). To search for additional genetic susceptibility loci underlying BMD variation, an effective strategy is to focus on testing of specific variants with high potential of functional effects. Single nucleotide p...

journal_title：International journal of genomics

authors： Qiu C,Shen H,Fu X,Xu C,Deng H

更新日期：2018-08-07 00:00:00

abstract：:We screened bacteria that use E2 as its sole source of carbon and energy for growth and identified them as Rhodococcus, and we named them DSSKP-R-001. For a better understanding of the metabolic potential of the strain, whole genome sequencing of Rhodococcus DSSKP-R-001 and annotation of the functional genes were perf...

journal_title：International journal of genomics

authors： Zhao H,Tian K,Qiu Q,Wang Y,Zhang H,Ma S,Jin S,Huo H

更新日期：2018-10-28 00:00:00

abstract：:Cancer is a multistep process characterized by various and different genetic lesions which cause the transformation of normal cells into tumor cells. To preserve the genomic integrity, eukaryotic cells need a complex DNA damage/repair response network of signaling pathways, involving many proteins, able to induce cell...

journal_title：International journal of genomics

authors： Tessitore A,Cicciarelli G,Del Vecchio F,Gaggiano A,Verzella D,Fischietti M,Vecchiotti D,Capece D,Zazzeroni F,Alesse E

更新日期：2014-01-01 00:00:00

abstract：:The wild Rubus species R. coreanus, which is widely distributed in southwest China, shows great promise as a genetic resource for breeding. One of its outstanding properties is adaptation to high temperature and humidity. To facilitate its use in selection and breeding programs, we assembled de novo 179,738,287 R. cor...

journal_title：International journal of genomics

authors： Chen Q,Liu X,Hu Y,Sun B,Hu Y,Wang X,Tang H,Wang Y

更新日期：2018-04-01 00:00:00

abstract：:Apicomplexan protist parasites utilize host sugars transported into the parasite by sugar transporter proteins for use as an energy source. We performed a phylum-wide phylogenetic analysis of the apicomplexan sugar transporter repertoire. Phylogenetic analyses revealed six major subfamilies of apicomplexan sugar trans...

journal_title：International journal of genomics

authors： Mahmud O,Kissinger JC

更新日期：2017-01-01 00:00:00

abstract：:To explore heat response mechanisms of mircoRNAs (miRNAs) in rice post-meiosis panicle, microarray analysis was performed on RNA isolated from rice post-meiosis panicles which were treated at 40°C for 0 min, 10 min, 20 min, 60 min, and 2 h. By integrating paired differentially expressed (DE) miRNAs and mRNA expression...

journal_title：International journal of genomics

authors： Peng Y,Zhang X,Liu Y,Chen X

更新日期：2020-09-17 00:00:00

abstract：:Goat plays a crucial role in human livelihoods, being a major source of meat, milk, fiber, and hides, particularly under adverse climatic conditions. The goat genomics related to the candidate gene approach is now being used to recognize molecular mechanisms that have different expressions of growth, reproductive, mil...

journal_title：International journal of genomics

authors： Zonaed Siddiki AMAM,Miah G,Islam MS,Kumkum M,Rumi MH,Baten A,Hossain MA

更新日期：2020-08-18 00:00:00

abstract：:Drought is the main environmental factor impairing hemp growth and yield. In order to decipher the molecular responses of hemp to drought stress, transcriptome changes of drought-stressed hemp (DS1 and DS2), compared to well-watered control hemp (CK1 and CK2), were studied with RNA-Seq technology. RNA-Seq generated 9....

journal_title：International journal of genomics

authors： Gao C,Cheng C,Zhao L,Yu Y,Tang Q,Xin P,Liu T,Yan Z,Guo Y,Zang G

更新日期：2018-05-15 00:00:00

abstract：:Puberty is a transition period where a child transforms to an adult. Puberty can be affected by various genetic factors and environmental influences. In mammals, the regulation of puberty is enhanced by the hypothalamic-pituitary-gonadal axis (HPG axis). A number of genes such as GnRH, Kiss1, and GPR54 have been repor...

journal_title：International journal of genomics

authors： Omariba G,Xiao J

更新日期：2020-05-22 00:00:00

abstract：:Pseudomonas aeruginosa PGPR2 is a mung bean rhizosphere strain that produces secondary metabolites and hydrolytic enzymes contributing to excellent antifungal activity against Macrophomina phaseolina, one of the prevalent fungal pathogens of mung bean. Genome sequencing was performed using the Ion Torrent Personal Gen...

journal_title：International journal of genomics

authors： Illakkiam D,Shankar M,Ponraj P,Rajendhran J,Gunasekaran P

更新日期：2014-01-01 00:00:00

abstract：:Rice grain shape and nutritional quality traits have high economic value for commercial production of rice and largely determine the market price, besides influencing the global food demand for high-quality rice. In order to understand the genetic components of grain appearance traits in paddy, brown, and head rice, 1...

journal_title：International journal of genomics

authors： Bazrkar-Khatibani L,Fakheri BA,Hosseini-Chaleshtori M,Mahender A,Mahdinejad N,Ali J

更新日期：2019-02-25 00:00:00

abstract：:The HIV-1 virus (human immunodeficiency virus) affects 36.9 million people worldwide, with approximately 900000 deaths in 2017. The virus carrier can develop severe immunodeficiency since CD4+ T lymphocytes are the main target, leading to acquired immunodeficiency syndrome (AIDS). Despite advances in pharmacological t...

journal_title：International journal of genomics

authors： Sanches-da-Silva GN,Medeiros LFS,Lima FM

更新日期：2019-08-21 00:00:00

abstract：:A population of 146 RILs (Recombinant Inbred Line) was derived from the cross between a cold-sensitive cultivated Solanum lycopersicum L. XF98-7 and a cold-tolerant wild Solanum pimpinellifolium LA2184. Relative germination ratio (RGR) and chilling index (CI) were used to evaluate the cold tolerance of the parental li...

journal_title：International journal of genomics

authors： Liu Y,Zhou T,Ge H,Pang W,Gao L,Ren L,Chen H

更新日期：2016-01-01 00:00:00

abstract：:The urinary metabolomic study based on gas chromatography-mass spectrometry (GC-MS) had been developed to investigate the possible antidepressant mechanism of chlorogenic acid (CGA) in a rat model of sleep deprivation (SD). According to pattern recognition analysis, there was a clear separation among big platform grou...

journal_title：International journal of genomics

authors： Ma WN,Zhou MM,Gou XJ,Zhao L,Cen F,Xu Y,Shen HY

更新日期：2018-02-11 00:00:00

abstract：:TSEN54 encodes a subunit of the tRNA-splicing endonuclease complex, which catalyzes the identification and cleavage of introns from precursor tRNAs. Previously, we identified an AluSx-derived alternative transcript in TSEN54 of cynomolgus monkey. Reverse transcription-polymerase chain reaction (RT-PCR) amplification a...

journal_title：International journal of genomics

authors： Lee JR,Kim YH,Park SJ,Choe SH,Cho HM,Lee SR,Kim SU,Kim JS,Sim BW,Song BS,Jeong KJ,Lee Y,Jin YB,Kang P,Huh JW,Chang KT

更新日期：2016-01-01 00:00:00

abstract：Background:Breast cancer development and progression involve both germline and somatic mutations. High-throughput genotyping and next-generation sequencing technologies have enabled discovery of genetic risk variants and acquired somatic mutations driving the disease. However, the possible oncogenic interactions betwee...

journal_title：International journal of genomics

authors： Wu J,Mamidi TKK,Zhang L,Hicks C

更新日期：2020-07-06 00:00:00

abstract：:Auxin response factors (ARFs) have been reported to play vital roles during plant growth and development. In order to reveal specific functions related to vegetative organs in grasses, an in-depth study of the ARF gene family was carried out in switchgrass (Panicum virgatum L.), a warm-season C4 perennial grass that i...

journal_title：International journal of genomics

authors： Wang J,Wu Z,Shen Z,Bai Z,Zhong P,Ma L,Pan D,Zhang R,Li D,Zhang H,Fu C,Han G,Guo C

更新日期：2018-04-29 00:00:00

abstract：:Orobanche crenata is a parasitic weed that causes considerable yield losses on food legumes in Ethiopia and the Mediterranean region. Understanding the genetic diversity of Orobanche crenata using molecular techniques generate useful information in managing the weed through resistance breeding. This study aimed at ass...

journal_title：International journal of genomics

authors： Belay G,Tesfaye K,Hamwieh A,Ahmed S,Dejene T,de Oliveira Júnior JOL

更新日期：2020-08-13 00:00:00

abstract：Background:Nonalcoholic fatty liver disease (NAFLD) has become a leading cause of liver transplantation. Lingguizhugan decoction (LGZG), a classical Chinese herbal formula, has beneficial effects on NAFLD animal models. Our study examined the impact of LGZG on hepatic global transcriptome of high-fat-diet-induced NAFLD...

journal_title：International journal of genomics

authors： Yang L,Lin W,Nugent CA,Hao S,Song H,Liu T,Zheng P

更新日期：2017-01-01 00:00:00

abstract：:Deep-sea fishes provide a unique opportunity to study the physiology and evolutionary adaptation to extreme environments. We carried out a high throughput sequencing analysis on a 454 GS-FLX titanium plate using unnormalized cDNA libraries from six tissues of A. carbo. Assemblage and annotations were performed by Newb...

journal_title：International journal of genomics

authors： Stefanni S,Bettencourt R,Pinheiro M,Moro GD,Bongiorni L,Pallavicini A

更新日期：2014-01-01 00:00:00

abstract：:Calmodulin II (CALM2) gene polymorphism might be responsible for the variation in the left ventricular mass amongst healthy individuals. The aim was to evaluate the correlation between left ventricular mass (LVM) and g.474955027G>A (rs7565161) polymorphism adjacent to the CALM2 gene. Healthy Polish newborns (n = 206) ...

journal_title：International journal of genomics

authors： Gorący I,Gorący J,Skonieczna-Żydecka K,Kaczmarczyk M,Dawid G,Ciechanowicz A

更新日期：2013-01-01 00:00:00

abstract：:High throughput genomic assays empower us to study the entire human genome in short time with reasonable cost. Formalin fixed-paraffin-embedded (FFPE) tissue processing remains the most economical approach for longitudinal tissue specimen storage. Therefore, the ability to apply high throughput genomic applications to...

journal_title：International journal of genomics

authors： Zhang P,Lehmann BD,Shyr Y,Guo Y

更新日期：2017-01-01 00:00:00

abstract：:Rett spectrum disorder is a progressive neurological disease and the most common genetic cause of intellectual disability in females. MECP2 is the major causative gene. In addition, CDKL5 and FOXG1 mutations have been reported in Rett patients, especially with the atypical presentation. Each gene and different mutatio...

journal_title：International journal of genomics

authors： Frullanti E,Papa FT,Grillo E,Clarke A,Ben-Zeev B,Pineda M,Bahi-Buisson N,Bienvenu T,Armstrong J,Roche Martinez A,Mari F,Nissenkorn A,Lo Rizzo C,Veneselli E,Russo S,Vignoli A,Pini G,Djuric M,Bisgaard AM,Ravn K,Bosn

更新日期：2019-03-27 00:00:00