Abstract:
:Drought is the main environmental factor impairing hemp growth and yield. In order to decipher the molecular responses of hemp to drought stress, transcriptome changes of drought-stressed hemp (DS1 and DS2), compared to well-watered control hemp (CK1 and CK2), were studied with RNA-Seq technology. RNA-Seq generated 9.83, 11.30, 11.66, and 11.31 M clean reads in the CK1, CK2, DS1, and DS2 libraries, respectively. A total of 1292 differentially expressed genes (DEGs), including 409 (31.66%) upregulated and 883 (68.34%) downregulated genes, were identified. The expression patterns of 12 selected genes were validated by qRT-PCR, and the results were accordant with Illumina analysis. Gene Ontology (GO) and KEGG analysis illuminated particular important biological processes and pathways, which enriched many candidate genes such as NAC, B3, peroxidase, expansin, and inositol oxygenase that may play important roles in hemp tolerance to drought. Eleven KEGG pathways were significantly influenced, the most influenced being the plant hormone signal transduction pathway with 15 differentially expressed genes. A similar expression pattern of genes involved in the abscisic acid (ABA) pathway under drought, and ABA induction, suggested that ABA is important in the drought stress response of hemp. These findings provide useful insights into the drought stress regulatory mechanism in hemp.
journal_name
Int J Genomicsjournal_title
International journal of genomicsauthors
Gao C,Cheng C,Zhao L,Yu Y,Tang Q,Xin P,Liu T,Yan Z,Guo Y,Zang Gdoi
10.1155/2018/3057272subject
Has Abstractpub_date
2018-05-15 00:00:00pages
3057272eissn
2314-436Xissn
2314-4378journal_volume
2018pub_type
杂志文章abstract::The yellow color of inner leaves in Chinese cabbage depends on its lutein and carotene content. To identify responsible genes for yellow pigmentation in leaves, the transcriptome profiles of white (Kenshin) and yellow leaves (Wheessen) were examined using the Br300K oligomeric chip in Chinese cabbage. In yellow leaves...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2014/204969
更新日期:2014-01-01 00:00:00
abstract:Purpose:Airway epithelium acts as a protective barrier against the particles from the inhaled air. Damage to the epithelium may result in loss of the barrier function. Epithelial repair in response to injury requires complex mechanisms, such as microRNA, small noncoding molecules, to regulate the processes involved in ...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2018/9093785
更新日期:2018-09-05 00:00:00
abstract::Paeonia lactiflora is a herbaceous flower in the family Paeoniaceae with both hypocotyl and epicotyl dormant seeds. We used high-throughput transcriptome sequencing on two different developmental stages of P. lactiflora seeds to identify seed dormancy and germination-related genes. We performed de novo assembly and an...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2017/8027626
更新日期:2017-01-01 00:00:00
abstract::Simple sequence repeats (SSRs) are among the most important markers for population analysis and have been widely used in plant genetic mapping and molecular breeding. Expressed sequence tag-SSR (EST-SSR) markers, located in the coding regions, are potentially more efficient for QTL mapping, gene targeting, and marker-...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2015/473028
更新日期:2015-01-01 00:00:00
abstract::A population of 146 RILs (Recombinant Inbred Line) was derived from the cross between a cold-sensitive cultivated Solanum lycopersicum L. XF98-7 and a cold-tolerant wild Solanum pimpinellifolium LA2184. Relative germination ratio (RGR) and chilling index (CI) were used to evaluate the cold tolerance of the parental li...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2016/3219276
更新日期:2016-01-01 00:00:00
abstract::Rheumatoid arthritis (RA) is an autoimmune disease characterized by the presence of antibodies against cyclic citrullinated peptide (anti-CCP), a consequence of the breakdown of immune tolerance. The lymphoid tyrosine phosphatase (Lyp) protein has significant effects on maintenance of peripheral immune tolerance. Two ...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2017/8753498
更新日期:2017-01-01 00:00:00
abstract::Photobacterium damselae subsp. damselae (PDD) is a Gram-negative bacterium that can infect a variety of aquatic organisms and humans. Based on an epidemiological investigation conducted over the past 3 years, PDD is one of the most important pathogens causing septic skin ulcer in deep-sea cage-cultured Sebastes schleg...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2019/4242653
更新日期:2019-04-10 00:00:00
abstract::The Chinese Kunming (KM) mouse is a widely used outbred mouse stock in China. However, its genetic structure remains unclear. In this study, we sequenced the genome of the C57BL/6J-Chr1KM (B6-Chr1KM) strain, the chromosome 1 (Chr 1) of which was derived from one KM mouse. With 36.6× average coverage of the entire geno...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2017/1712530
更新日期:2017-01-01 00:00:00
abstract::Taxol is one of the most potent and effective anticancer drugs and is originally isolated from Taxus species. To investigate the specific regulatory mechanisms of taxol synthesis in Taxus wallichiana var. mairei, RNA-seq was conducted to reveal the differences in transcriptional levels between wild type (WT) and "Jinx...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2019/1596895
更新日期:2019-05-02 00:00:00
abstract::Orobanche crenata is a parasitic weed that causes considerable yield losses on food legumes in Ethiopia and the Mediterranean region. Understanding the genetic diversity of Orobanche crenata using molecular techniques generate useful information in managing the weed through resistance breeding. This study aimed at ass...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2020/3202037
更新日期:2020-08-13 00:00:00
abstract::The threat of heat stress on crop production increased dramatically due to global warming leading to the rise on the demand of heat-tolerant crops and understanding their tolerance. The leguminous forage crop Guar [Cyamopsis tetragonoloba (L.) Taub] is a high-temperature tolerant plant with numerous works on its toler...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2020/3126592
更新日期:2020-06-19 00:00:00
abstract::Calmodulin II (CALM2) gene polymorphism might be responsible for the variation in the left ventricular mass amongst healthy individuals. The aim was to evaluate the correlation between left ventricular mass (LVM) and g.474955027G>A (rs7565161) polymorphism adjacent to the CALM2 gene. Healthy Polish newborns (n = 206) ...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2013/410407
更新日期:2013-01-01 00:00:00
abstract::The purpose of this work was to study changes in the level of cell-free DNA (cfDNA) in the blood of young and old rats in the normal state and with induced benign prostatic hyperplasia (BPH). Male Wistar rats were divided into 4 groups-young (3 months), old (20 months), intact, or with testosterone-induced BPH. Groups...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2019/8173630
更新日期:2019-06-02 00:00:00
abstract::The Gene Ontology (GO) provides a resource for consistent annotation of genes and gene products that is extensively used by numerous large public repositories. The GO is constructed of three subontologies describing the cellular component of action, molecular function, and overall biological process of a gene or gene ...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2013/594528
更新日期:2013-01-01 00:00:00
abstract::Insulin resistance has a central role in the pathogenesis of several metabolic diseases, including type 2 diabetes, obesity, glucose intolerance, metabolic syndrome, atherosclerosis, and cardiovascular diseases. Insulin resistance and related traits are likely to be caused by abnormalities in the genes encoding for pr...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2013/376454
更新日期:2013-01-01 00:00:00
abstract::To explore heat response mechanisms of mircoRNAs (miRNAs) in rice post-meiosis panicle, microarray analysis was performed on RNA isolated from rice post-meiosis panicles which were treated at 40°C for 0 min, 10 min, 20 min, 60 min, and 2 h. By integrating paired differentially expressed (DE) miRNAs and mRNA expression...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2020/7582612
更新日期:2020-09-17 00:00:00
abstract::Rett spectrum disorder is a progressive neurological disease and the most common genetic cause of intellectual disability in females. MECP2 is the major causative gene. In addition, CDKL5 and FOXG1 mutations have been reported in Rett patients, especially with the atypical presentation. Each gene and different mutatio...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2019/6956934
更新日期:2019-03-27 00:00:00
abstract::Rice grain shape and nutritional quality traits have high economic value for commercial production of rice and largely determine the market price, besides influencing the global food demand for high-quality rice. In order to understand the genetic components of grain appearance traits in paddy, brown, and head rice, 1...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2019/3160275
更新日期:2019-02-25 00:00:00
abstract::Apicomplexan protist parasites utilize host sugars transported into the parasite by sugar transporter proteins for use as an energy source. We performed a phylum-wide phylogenetic analysis of the apicomplexan sugar transporter repertoire. Phylogenetic analyses revealed six major subfamilies of apicomplexan sugar trans...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2017/1707231
更新日期:2017-01-01 00:00:00
abstract::Arabidopsis thaliana (L.) Heynh. is a model organism of plant molecular biology. More than 1,700 whole genome sequences have been sequenced, but no Korean isolate genomes have been sequenced thus far despite the fact that many A. thaliana isolated in Japan and China have been sequenced. To understand the genetic backg...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2020/3236461
更新日期:2020-09-05 00:00:00
abstract::Determining protein-protein interaction (PPI) in biological systems is of considerable importance, and prediction of PPI has become a popular research area. Although different classifiers have been developed for PPI prediction, no single classifier seems to be able to predict PPI with high confidence. We postulated th...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2015/608042
更新日期:2015-01-01 00:00:00
abstract::The expression level of each gene is controlled by its regulatory regions, which determine the precise regulation in a tissue-specific manner, according to the developmental stage of the body and the necessity of a response to external stimuli. Nucleotide substitutions in regulatory gene regions may modify the affinit...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2015/260159
更新日期:2015-01-01 00:00:00
abstract::In general, mutation frequencies are context-dependent: specific adjacent nucleotides may influence the probability to observe a specific type of mutation in a genome. Recently, several hypermutable motifs were identified in the human genome. Namely, there is an increased frequency of T>C mutations in the second posit...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2013/173616
更新日期:2013-01-01 00:00:00
abstract::Puberty is a transition period where a child transforms to an adult. Puberty can be affected by various genetic factors and environmental influences. In mammals, the regulation of puberty is enhanced by the hypothalamic-pituitary-gonadal axis (HPG axis). A number of genes such as GnRH, Kiss1, and GPR54 have been repor...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2020/1426761
更新日期:2020-05-22 00:00:00
abstract::Severe gastroenteritis and foodborne illness caused by Noroviruses (NoVs) during the winter are a worldwide phenomenon. Vulnerable populations including young children and elderly and immunocompromised people often require hospitalization and may die. However, no efficient vaccine for NoVs exists because of their vari...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2013/456356
更新日期:2013-01-01 00:00:00
abstract::Osteoporosis is a serious public health issue, which is mostly characterized by low bone mineral density (BMD). To search for additional genetic susceptibility loci underlying BMD variation, an effective strategy is to focus on testing of specific variants with high potential of functional effects. Single nucleotide p...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2018/6407257
更新日期:2018-08-07 00:00:00
abstract::Pseudomonas aeruginosa PGPR2 is a mung bean rhizosphere strain that produces secondary metabolites and hydrolytic enzymes contributing to excellent antifungal activity against Macrophomina phaseolina, one of the prevalent fungal pathogens of mung bean. Genome sequencing was performed using the Ion Torrent Personal Gen...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2014/123058
更新日期:2014-01-01 00:00:00
abstract:Background:Breast cancer development and progression involve both germline and somatic mutations. High-throughput genotyping and next-generation sequencing technologies have enabled discovery of genetic risk variants and acquired somatic mutations driving the disease. However, the possible oncogenic interactions betwee...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2020/2641370
更新日期:2020-07-06 00:00:00
abstract::Paulownia witches' broom caused by phytoplasma infection affects the production of Paulownia trees worldwide. Emerging evidence showed that long noncoding RNAs (lncRNA) play a protagonist role in regulating the expression of genes in plants. So far, the identification of lncRNAs has been limited to a few model plant s...
journal_title:International journal of genomics
pub_type: 杂志文章
doi:10.1155/2018/3174352
更新日期:2018-02-21 00:00:00
abstract::In recent years the human microbiome has become a growing area of research and it is becoming clear that the microbiome of humans plays an important role for human health. Extensive research is now going into cataloging and annotating the functional role of the human microbiome. The ability to explore and describe the...
journal_title:International journal of genomics
pub_type: 杂志文章,评审
doi:10.1155/2016/5304028
更新日期:2016-01-01 00:00:00