[68Ga]Pentixafor-PET/MRI for the detection of Chemokine receptor 4 expression in atherosclerotic plaques.

abstract：PURPOSE:Sympathetic nervous system (SNS) hyperactivity is a salient characteristic of chronic heart failure (HF) and contributes to the progression of the disease. Iodine-123 meta-iodobenzylguanidine (123I-mIBG) imaging has been successfully used to assess cardiac SNS activity in HF patients and to predict prognosis. I...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rengo G,Pagano G,Vitale DF,Formisano R,Komici K,Petraglia L,Parisi V,Femminella GD,de Lucia C,Paolillo S,Cannavo A,Attena E,Pellegrino T,Dellegrottaglie S,Memmi A,Trimarco B,Cuocolo A,Filardi PP,Leosco D,Ferrara N

更新日期：2016-12-01 00:00:00

abstract：:Paragangliomas or glomus tumours of the head and neck region are rare somatostatin receptor-expressing neuroendocrine tumours. Precise preoperative diagnosis is of special importance in order to adequately weigh the potential benefit of the operation against the inherent risks of the procedure. In this study, the clin...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Schmidt M,Fischer E,Dietlein M,Michel O,Weber K,Moka D,Stennert E,Schicha H

更新日期：2002-12-01 00:00:00

abstract：PURPOSE:The histamine H3 receptors are presynaptic neuroreceptors that inhibit the release of histamine and other neurotransmitters. The receptors are considered a drug target for sleep disorders and neuropsychiatric disorders with cognitive decline. We developed a novel PET ligand for the H3 receptors, [(11)C]TASP0410...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kimura Y,Seki C,Ikoma Y,Ichise M,Kawamura K,Takahata K,Moriguchi S,Nagashima T,Ishii T,Kitamura S,Niwa F,Endo H,Yamada M,Higuchi M,Zhang MR,Suhara T

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Although( 18)F-fluorodeoxyglucose (FDG) PET is an established imaging technique to assess brain glucose utilisation, accurate measurement of tracer concentration is confounded by the presence of partial volume effect (PVE) due to the limited spatial resolution of PET, which is particularly true in atrophic brai...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Samuraki M,Matsunari I,Chen WP,Yajima K,Yanase D,Fujikawa A,Takeda N,Nishimura S,Matsuda H,Yamada M

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:(18)F-Fluoride PET/CT is a relatively undervalued diagnostic test to measure bone metabolism in bone diseases. Hyperostosis cranialis interna (HCI) is a (hereditary) bone disease characterised by endosteal hyperostosis and osteosclerosis of the skull and the skull base. Bone overgrowth causes entrapment and dys...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Waterval JJ,Van Dongen TM,Stokroos RJ,Teule JG,Kemerink GJ,Brans B,Nieman FH,Manni JJ

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:As hypoxia is believed to play an important role in the development and progression of prostate cancer, we evaluated whether 18F-labeled fluoroazomycin arabinoside (18F-FAZA) would be useful to identify tumor hypoxia in resectable prostate cancer. METHODS:Positron emission tomography (PET)/CT was performed on ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Garcia-Parra R,Wood D,Shah RB,Siddiqui J,Hussain H,Park H,Desmond T,Meyer C,Piert M

更新日期：2011-10-01 00:00:00

abstract：PURPOSE:To investigate the value of 68Ga-HBED-CC PSMA (68Ga-PSMA) PET/CT for response assessment in metastatic castration-sensitive and castration-resistant prostate cancer (mCSPC and mCRPC) during docetaxel chemotherapy. METHODS:68Ga-PSMA PET/CT was performed in seven mCSPC patients before and after six cycles of upf...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Seitz AK,Rauscher I,Haller B,Krönke M,Luther S,Heck MM,Horn T,Gschwend JE,Schwaiger M,Eiber M,Maurer T

更新日期：2018-04-01 00:00:00

abstract：PURPOSE:Radioembolization (RE) is a promising treatment option for biliary tract cancers (BTC). We report here the largest series to date using this treatment modality. METHODS:We retrospectively studied data from 64 patients treated outside prospective clinical trial at our institution. We studied baseline characteri...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bourien H,Palard X,Rolland Y,Le Du F,Beuzit L,Uguen T,Le Sourd S,Pracht M,Manceau V,Lièvre A,Boudjema K,Garin E,Edeline J

更新日期：2019-03-01 00:00:00

abstract：:The goal of this study was to perform a systematic, semi-quantitative analysis of limbic perfusion in patients with Alzheimer's disease (AD) using coregistered single-photon emission tomography (SPET) images aligned to magnetic resonance (MR) images. Limbic perfusion in 40 patients with mild to moderate AD was compare...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Callen DJ,Black SE,Caldwell CB

更新日期：2002-07-01 00:00:00

abstract：PURPOSE:PET imaging has been recently introduced for investigating the type 1 angiotensin II receptor (AT(1)R) in vivo. The goal of the present study was to investigate the effects of acute and chronic exposure to angiotensin converting enzyme inhibitors (ACEI) on the AT(1)R in the dog kidney. METHODS:Animals were ima...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zober TG,Fabucci ME,Zheng W,Brown PR,Seckin E,Mathews WB,Sandberg K,Szabo Z

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:To examine the diagnostic performance of (18)F-fluorothymidine (FLT) PET/CT in primary and metastatic lymph node colorectal cancer foci in comparison with (18)F-fluorodeoxyglucose (FDG) PET/CT. METHODS:The study population comprised 28 patients with 30 newly diagnosed colorectal cancers who underwent surgical ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nakajo M,Nakajo M,Kajiya Y,Jinguji M,Nishimata N,Shimaoka S,Nihara T,Aridome K,Tanaka S,Fukukura Y,Tani A,Koriyama C

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:123I-labelled mZIENT (2β-carbomethoxy-3β-(3′-((Z)-2-iodoethenyl)phenyl)nortropane) has been developed as a radioligand for the serotonin transporter. The aim of this preliminary study was to assess its whole-body biodistribution in humans and estimate dosimetry. METHODS:Three healthy controls and three patient...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nicol A,Krishnadas R,Champion S,Tamagnan G,Stehouwer JS,Goodman MM,Hadley DM,Pimlott SL

更新日期：2012-05-01 00:00:00

abstract：:In locally advanced head and neck squamous cell carcinoma (HNSCC), the role of imaging becomes more and more critical in the management process. In this framework, molecular imaging techniques such as PET allow noninvasive assessment of a range of tumour biomarkers such as metabolism, hypoxia and proliferation, which ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Differding S,Hanin FX,Grégoire V

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:[(18)F]Fluciclovine (anti-[(18)F]FACBC) is a synthetic amino acid developed for PET assessment of the anabolic component of tumour metabolism in clinical routine. This phase 1 trial evaluated the safety, tracer stability and uptake kinetics of [(18)F]fluciclovine in patients. METHODS:Six patients with biopsy-p...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sörensen J,Owenius R,Lax M,Johansson S

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:To report on imaging findings using 68Ga-PSMA-HBED-CC PET in a series of 19 breast carcinoma patients. METHODS:68Ga-PSMA-HBED-CC PET imaging results obtained were compared to routinely performed staging examinations and analyzed as to lesion location and progesterone receptor status. RESULTS:Out of 81 tumo...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sathekge M,Lengana T,Modiselle M,Vorster M,Zeevaart J,Maes A,Ebenhan T,Van de Wiele C

更新日期：2017-04-01 00:00:00

abstract：:In prostate cancer, confirmation of metastatic involvement of the skeleton has traditionally been achieved by bone scintigraphy, although the widespread availability of prostate-specific antigen (PSA) measurements has tended to eliminate the need for this investigation. The potential of bone scintigraphy to predict sk...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Soerdjbalie-Maikoe V,Pelger RC,Lycklama à Nijeholt GA,Arndt JW,Zwinderman AH,Bril H,Papapoulos SE,Hamdy NA

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:Quantitative PET/MR imaging is challenged by the accuracy of synthetic CT (sCT) generation from MR images. Deep learning-based algorithms have recently gained momentum for a number of medical image analysis applications. In this work, a novel sCT generation algorithm based on deep learning adversarial semanti...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Arabi H,Zeng G,Zheng G,Zaidi H

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:Antagonism of norepinephrine reuptake is now an important pharmacological strategy in the treatment of anxiety and depressive disorders, and many antidepressants have substantial potential occupancy of the norepinephrine transporter (NET) at recommended dosages. Despite the importance of understanding this tran...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Severance AJ,Milak MS,Kumar JSD,Prabhakaran J,Majo VJ,Simpson NR,Van Heertum RL,Arango V,Mann JJ,Parsey RV

更新日期：2007-05-01 00:00:00

abstract：PURPOSE:The folate receptor (FR) is frequently overexpressed in a variety of tumor types and, hence, an interesting target for radionuclide therapy. The aim of this study was to evaluate a new class of albumin-binding radioconjugates comprising 5-methyltetrahydrofolate (5-MTHF) as a targeting agent and to compare their...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Guzik P,Benešová M,Ratz M,Monné Rodríguez JM,Deberle LM,Schibli R,Müller C

更新日期：2020-10-15 00:00:00

abstract：PURPOSE:Angiotensin-converting enzyme (ACE) and soluble interleukin-2 receptor (sIL-2R) are serological markers, widely used for determining sarcoidosis activity. (18)F-FDG PET has proven to be a sensitive technique in the imaging of sarcoidosis. The aim of this study was to determine sensitivity of (18)F-FDG PET, geno...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Keijsers RG,Verzijlbergen FJ,Oyen WJ,van den Bosch JM,Ruven HJ,van Velzen-Blad H,Grutters JC

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:The aims of this study were (1) to evaluate FDG PET/CT and CT for the detection of axillary lymph node metastases in breast cancer (BC) patients and (2) to evaluate FDG PET/CT as a pre-test for the triage to sentinel lymph node biopsy (SLNB) versus axillary lymph node dissection (ALND). METHODS:The sensitivity...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Heusner TA,Kuemmel S,Hahn S,Koeninger A,Otterbach F,Hamami ME,Kimmig KR,Forsting M,Bockisch A,Antoch G,Stahl A

更新日期：2009-10-01 00:00:00

abstract：PURPOSE:To determine the impact on clinical management of patients with high-risk (HR) prostate cancer at diagnosis and patients with biochemical recurrence (BCR) using a new kit form of 68Ga-prostate-specific membrane antigen (PSMA), namely tris(hydroxypyridinone) (THP)-PSMA, with positron emission tomography-computed...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kulkarni M,Hughes S,Mallia A,Gibson V,Young J,Aggarwal A,Morris S,Challacombe B,Popert R,Brown C,Cathcart P,Dasgupta P,Warbey VS,Cook GJR

更新日期：2020-03-01 00:00:00

abstract：:It has been suggested that determination of differential renal function (DRF)using technetium-99m dimercaptosuccinic acid (DMSA) may lead to overestimation of the function of an obstructed kidney in patients with excretion abnormalities owing to pelvic retention of DMSA. Recently published guidelines have recommended ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kabasakal L,Turkmen C,Ozmen O,Alan N,Onsel C,Uslu I

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:To contribute to the differentiation of Parkinson's disease (PD) and essential tremor (ET), we compared two different artificial neural network classifiers using (123)I-FP-CIT SPECT data, a probabilistic neural network (PNN) and a classification tree (ClT). METHODS:(123)I-FP-CIT brain SPECT with semiquantitati...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Palumbo B,Fravolini ML,Nuvoli S,Spanu A,Paulus KS,Schillaci O,Madeddu G

更新日期：2010-11-01 00:00:00

abstract：PURPOSE:Facilitation of the ability of neuronal lineages derived from transplanted stem cells to differentiate is essential to improve the low efficacy of neuronal differentiation in stem cell therapy in vivo. Neurogenin 1 (Ngn1), a basic helix-loop-helix factor, has been used as an activator of neuronal differentiatio...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Oh HJ,Hwang DW,Youn H,Lee DS

更新日期：2013-10-01 00:00:00

abstract：:Oesophageal scintigraphy has been used for more than 25 years and allows quantifiable, safe, rapid, non-invasive and well-tolerated assessment of oesophageal transit time and function. As technology improves, more complex image analysis is becoming possible. Many studies have addressed its usefulness in assessing oeso...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Stacey B,Patel P

更新日期：2002-09-01 00:00:00

abstract：INTRODUCTION:Vascular prosthesis infection (VPI) is a life-threatening complication that occurs in 0.5-5% of prostheses. Low-grade infections in non-acute patients are a diagnostic challenge requiring a new method with good diagnostic accuracy. The aim of this work was to define the accuracy of (18)F-FDG PET/CT in thes...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Spacek M,Belohlavek O,Votrubova J,Sebesta P,Stadler P

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:PET has been proven to be helpful in the delineation of gross tumour volume (GTV) for external radiation therapy in several tumour entities. The aim of this study was to determine if [(11)C]choline PET could be used to localize the carcinomatous tissue within the prostate in order to specifically target this ar...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bundschuh RA,Wendl CM,Weirich G,Eiber M,Souvatzoglou M,Treiber U,Kübler H,Maurer T,Gschwend JE,Geinitz H,Grosu AL,Ziegler SI,Krause BJ

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:Our aim was to assess the prognostic and predictive value of somatostatin receptor 2 (sstr2) in neuroendocrine tumors (NETs). METHODS:We established a tissue microarray and imaging database from NET patients that received sstr2-targeted radiopeptide therapy with yttrium-90-DOTATOC, lutetium-177-DOTATOC or alte...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brunner P,Jörg AC,Glatz K,Bubendorf L,Radojewski P,Umlauft M,Marincek N,Spanjol PM,Krause T,Dumont RA,Maecke HR,Müller-Brand J,Briel M,Schmitt A,Perren A,Walter MA

更新日期：2017-03-01 00:00:00

abstract：PURPOSE:Both head and neck magnetic resonance imaging (MRI) and 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) play a crucial role in the staging of primary nasopharyngeal carcinoma (NPC). In this study, we sought to prospectively investigate the clinical utility of simulta...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Chan SC,Yeh CH,Yen TC,Ng SH,Chang JT,Lin CY,Yen-Ming T,Fan KH,Huang BS,Hsu CL,Chang KP,Wang HM,Liao CT

更新日期：2018-07-01 00:00:00